Richard Jove

Overview

Best Publications

• STATs in cancer inflammation and immunity: a leading role for STAT3

  Hua Yu;Drew Pardoll;Richard Jove

  4940
  Citations

• The STATs of cancer — new molecular targets come of age

  Hua Yu;Richard Jove

  3203
  Citations

• Revisiting STAT3 signalling in cancer: new and unexpected biological functions

  Hua Yu;Heehyoung Lee;Andreas Herrmann;Ralf Buettner

  2442
  Citations

• Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells

  Robyn Catlett-Falcone;Terry H Landowski;Marc M Oshiro;James Turkson

  2147
  Citations

• Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

  Guilian Niu;Kenneth L Wright;Mei Huang;Lanxi Song

  1588
  Citations

• Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells.

  Tianhong Wang;Guilian Niu;Marcin Kortylewski;Lyudmila Burdelya

  1474
  Citations

• Activated STAT Signaling in Human Tumors Provides Novel Molecular Targets for Therapeutic Intervention

  Ralf Buettner;Linda B Mora;Richard Jove

  1463
  Citations

• Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

  Chao Lan Yu;Debra J. Meyer;George S. Campbell;Andrew C. Larner

  1413
  Citations

• Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity.

  Marcin Kortylewski;Maciej Kujawski;Tianhong Wang;Sheng Wei

  1282
  Citations

• Stat3 Activation by Src Induces Specific Gene Regulation and Is Required for Cell Transformation

  James Turkson;Tammy Bowman;Roy Garcia;Eric Caldenhoven

  1021
  Citations

• Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells.

  Roy Garcia;Tammy L Bowman;Guilian Niu;Hua Yu

  985
  Citations

• Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression

  P. K. Epling-Burnette;Jin Hong Liu;Robyn Catlett-Falcone;James Turkson

  924
  Citations

• Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity

  Khandaker Siddiquee;Shumin Zhang;Wayne C. Guida;Michelle A. Blaskovich

  903
  Citations

• Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice.

  Michelle A. Blaskovich;Jiazhi Sun;Alan Cantor;James Turkson

  862
  Citations

• Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors

  Heehyoung Lee;Andreas Herrmann;Jie Hui Deng;Maciej Kujawski

  860
  Citations

• Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways

  Qing Xu;Jon Briggs;Sungman Park;Guilian Niu

  748
  Citations

• Constitutive Activation of Stat3 in Human Prostate Tumors and Cell Lines Direct Inhibition of Stat3 Signaling Induces Apoptosis of Prostate Cancer Cells

  Linda B Mora;Ralf Buettner;John Seigne;Jose Diaz

  730
  Citations

• Persistent Activation of Stat3 Signaling Induces Survivin Gene Expression and Confers Resistance to Apoptosis in Human Breast Cancer Cells

  Tanya Gritsko;Ann Williams;James Turkson;Satoshi Kaneko

  704
  Citations

• Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis

  Tammy Bowman;Martin A. Broome;Dominic Sinibaldi;Walker Wharton

  701
  Citations

• JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance.

  Tianyi Wang;Tianyi Wang;Johannes Francois Fahrmann;Heehyoung Lee;Yi Jia Li

  680
  Citations