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Said M. Sebti

D-Index & Metrics

Biology and Biochemistry

D-Index
103
Citations
32727
World Ranking
1327
National Ranking
777

Said M. Sebti publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Said M. Sebti sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 456 publications — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Said M. Sebti D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Said M. Sebti sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 103 D-Index — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2014 - Fellow, National Academy of Inventors

Overview

Said M. Sebti is affiliated with Virginia Commonwealth University in the United States. Their research spans multiple fields including Medicine, Biochemistry, Genetics and Molecular Biology, as well as Immunology and Microbiology. The scientist's work focuses on several subfields such as Molecular Biology, Immunology, Oncology, Radiology, Nuclear Medicine and Imaging, and Cancer Research.

Their main research topics include:

  • CAR-T cell therapy research
  • Immune Cell Function and Interaction
  • Mast cells and histamine
  • Monoclonal and Polyclonal Antibodies Research
  • Cancer-related Molecular Pathways
  • Immunotherapy and Immune Responses
  • PI3K/AKT/mTOR signaling in cancer

Sebti has authored various papers published in noted journals. Recent publications include:

  • "CD28 Costimulatory Domain-Targeted Mutations Enhance Chimeric Antigen Receptor T-cell Function" (2020), Cancer Immunology Research
  • "Global Phosphoproteomics Reveal CDK Suppression as a Vulnerability to KRas Addiction in Pancreatic Cancer" (2021), Clinical Cancer Research
  • "The GTPase KRAS suppresses the p53 tumor suppressor by activating the NRF2-regulated antioxidant defense system in cancer cells" (2020), Journal of Biological Chemistry
  • "Pacritinib Combined with Sirolimus and Low-Dose Tacrolimus for GVHD Prevention after Allogeneic Hematopoietic Cell Transplantation: Preclinical and Phase I Trial Results" (2021), Clinical Cancer Research
  • "Porphyrin overdrive rewires cancer cell metabolism" (2024), Life Science Alliance

Frequent co-authors collaborating with Said M. Sebti include:

  • Aslamuzzaman Kazi
  • Elizabeth M. Sagatys
  • Kelly Walton
  • Jongphil Kim
  • Nicholas J. Lawrence

The scientist publishes regularly in prominent venues such as:

  • The Journal of Immunology
  • Blood
  • Cancer Immunology Research
  • Clinical Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)

Said M. Sebti was recognized as a Fellow of the National Academy of Inventors in 2014.

Best Publications

  • Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity

    Khandaker Siddiquee;Shumin Zhang;Wayne C. Guida;Michelle A. Blaskovich

  • Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice.

    Michelle A. Blaskovich;Jiazhi Sun;Alan Cantor;James Turkson

  • Targeting protein prenylation for cancer therapy

    Norbert Berndt;Andrew D. Hamilton;Saïd M. Sebti

  • Akt/Protein Kinase B Signaling Inhibitor-2, a Selective Small Molecule Inhibitor of Akt Signaling with Antitumor Activity in Cancer Cells Overexpressing Akt

    Lin Yang;Han C. Dan;Mei Sun;Qiyuan Liu

  • Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation.

    James Turkson;Declan Ryan;Joon S. Kim;Yi Zhang

  • Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes.

    Edwina C. Lerner;Yimin Qian;Michelle A. Blaskovich;Renae D. Fossum

  • Protein geranylgeranylation is required for osteoclast formation, function, and survival: inhibition by bisphosphonates and GGTI-298.

    Fraser P. Coxon;Miep H. Helfrich;Robert Van't Hof;Saïd Sebti

  • Regulation of Dendritic Cell Differentiation and Antitumor Immune Response in Cancer by Pharmacologic-Selective Inhibition of the Janus-Activated Kinase 2/Signal Transducers and Activators of Transcription 3 Pathway

    Yulia Nefedova;Srinivas Nagaraj;Amsler Rosenbauer;Carlos Muro-Cacho

  • Farnesyltransferase and geranylgeranyltransferase I inhibitors and cancer therapy: lessons from mechanism and bench-to-bedside translational studies.

    Saïd M Sebti;Andrew D Hamilton

  • The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis

    Kun Jiang;Domenico Coppola;Nichole C. Crespo;Santo V. Nicosia

  • Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein.

    James Turkson;Tammy Bowman;Jalila Adnane;Yi Zhang

  • Cucurbitacin Q: a selective STAT3 activation inhibitor with potent antitumor activity.

    Jiazhi Sun;Michelle A Blaskovich;Richard Jove;Sandra K Livingston

  • Discovery of a novel shp2 protein tyrosine phosphatase inhibitor.

    Liwei Chen;Shen Shu Sung;M. L Richard Yip;Harshani R. Lawrence

  • Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts.

    Jiazhi Sun;Yimin Qian;Andrew D Hamilton;Saïd M Sebti

  • Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity

    James Turkson;Joon S. Kim;Shumin Zhang;Jing Yuan

  • Antitumor efficacy of a novel class of non-thiol-containing peptidomimetic inhibitors of farnesyltransferase and geranylgeranyltransferase I: Combination therapy with the cytotoxic agents cisplatin, taxol, and gemcitabine

    Jiazhi Sun;Michelle A. Blaskovich;David Knowles;Yimin Qian

  • Terphenyl-based helical mimetics that disrupt the p53/HDM2 interaction.

    Hang Yin;Gui‐in Lee;Hyung Soon Park;Gregory A. Payne

  • MDMX Overexpression Prevents p53 Activation by the MDM2 Inhibitor Nutlin

    Baoli Hu;Daniele M. Gilkes;Bilal Farooqi;Said M. Sebti

  • Ras CAAX Peptidomimetic FTI 276 Selectively Blocks Tumor Growth in Nude Mice of a Human Lung Carcinoma with K-Ras Mutation and p53 Deletion

    Jiazhi Sun;Yimin Qian;Andrew D. Hamilton;Saïd M. Sebti

  • Terphenyl-Based Bak BH3 α-Helical Proteomimetics as Low-Molecular-Weight Antagonists of Bcl-xL

    Hang Yin;Gui In Lee;Kristine A. Sedey;Olaf Kutzki

Frequent Co-Authors

Andrew D. Hamilton
Andrew D. Hamilton New York University
Jin Q. Cheng
Jin Q. Cheng University of South Florida
Jie Wu
Jie Wu Temple University
Domenico Coppola
Domenico Coppola Moffitt Cancer Center
Richard Jove
Richard Jove Nova Southeastern University
Michael H. Gelb
Michael H. Gelb University of Washington
Wesley C. Van Voorhis
Wesley C. Van Voorhis University of Washington
Frederick S. Buckner
Frederick S. Buckner University of Washington
Srikumar Chellappan
Srikumar Chellappan University of South Florida
Hong-Gang Wang
Hong-Gang Wang Pennsylvania State University

External Links

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Best Scientists Citing Said M. Sebti

Andrew D. Hamilton

Andrew D. Hamilton

New York University

Publications: 70

Michael J. Rogers

Michael J. Rogers

Garvan Institute of Medical Research

Publications: 47

Fuyuhiko Tamanoi

Fuyuhiko Tamanoi

Kyoto University

Publications: 42

Richard Jove

Richard Jove

Nova Southeastern University

Publications: 38

Hong-Gang Wang

Hong-Gang Wang

Pennsylvania State University

Publications: 37

Thomas P. Loughran

Thomas P. Loughran

University of Virginia

Publications: 35

Jianfeng Cai

Jianfeng Cai

University of South Florida

Publications: 35

Channing J. Der

Channing J. Der

University of North Carolina at Chapel Hill

Publications: 35

Hua Yu

Hua Yu

City Of Hope National Medical Center

Publications: 32

Fadlo R. Khuri

Fadlo R. Khuri

American University of Beirut

Publications: 30

Jin Q. Cheng

Jin Q. Cheng

University of South Florida

Publications: 30

Domenico Coppola

Domenico Coppola

Moffitt Cancer Center

Publications: 28

Michael H. Gelb

Michael H. Gelb

University of Washington

Publications: 28

Adrienne D. Cox

Adrienne D. Cox

University of North Carolina at Chapel Hill

Publications: 28

Dmitry I. Gabrilovich

Dmitry I. Gabrilovich

AstraZeneca (United Kingdom)

Publications: 27

David A. Frank

David A. Frank

Harvard University

Publications: 26

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