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Fuyuhiko Tamanoi

Fuyuhiko Tamanoi

D-Index & Metrics

Biology and Biochemistry

D-Index
83
Citations
24619
World Ranking
3500
National Ranking
214

Overview

Fuyuhiko Tamanoi is affiliated with Kyoto University in Japan and contributes to multiple scientific fields, primarily focused on biochemistry, genetics, molecular biology, materials science, and medicine. Their research outputs encompass molecular biology, materials chemistry, biomaterials, radiology, nuclear medicine, imaging, pulmonary, and respiratory medicine.

The scientist's work extensively covers several interconnected topics in the biomedical and material sciences landscape. These include:

  • Nanoparticle-Based Drug Delivery
  • Boron Compounds in Chemistry
  • Radiation Therapy and Dosimetry
  • Mesoporous Materials and Catalysis
  • Nuclear Physics and Applications
  • Electron and X-Ray Spectroscopy Techniques
  • DNA Repair Mechanisms

Fuyuhiko Tamanoi has published in a number of frequent venues such as:

  • The Enzymes
  • ACS Applied Materials & Interfaces
  • Scientific Reports
  • Nanoscale Advances
  • Cells

The following is a selection of recent papers authored or co-authored by Tamanoi, spanning from 2020 to 2021:

  • Cytosolic and mitochondrial ROS production resulted in apoptosis induction in breast cancer cells treated with Crocin: The role of FOXO3a, PTEN and AKT signaling (2020), published in Biochemical Pharmacology
  • Designing Mesoporous Silica Nanoparticles to Overcome Biological Barriers by Incorporating Targeting and Endosomal Escape (2021), published in ACS Applied Materials & Interfaces
  • Biodegradable Periodic Mesoporous Organosilica (BPMO) Loaded with Daunorubicin: A Promising Nanoparticle-Based Anticancer Drug (2020), published in ChemMedChem
  • Recent Development to Explore the Use of Biodegradable Periodic Mesoporous Organosilica (BPMO) Nanomaterials for Cancer Therapy (2020), published in Pharmaceutics
  • Construction of Boronophenylalanine-Loaded Biodegradable Periodic Mesoporous Organosilica Nanoparticles for BNCT Cancer Therapy (2021), published in International Journal of Molecular Sciences

Collaboration is a significant aspect of Tamanoi's research activity. Frequent co-authors include:

  • Kotaro Matsumoto
  • Aoi Komatsu
  • Tân Lê Hoàng Đoàn
  • Yuya Higashi
  • Ngoc Xuan Dat

This profile indicates a strong engagement with nanoparticle-based cancer therapies and the development of biodegradable organosilica nanomaterials. The research integrates biological, chemical, and material science approaches, particularly applied to cancer treatment modalities and drug delivery systems.

Best Publications

  • Multifunctional Inorganic Nanoparticles for Imaging, Targeting, and Drug Delivery

    Monty Liong;Jie Lu;Michael Kovochich;Tian Xia

  • Mesoporous Silica Nanoparticles as a Delivery System for Hydrophobic Anticancer Drugs

    Jie Lu;Monty Liong;Jeffrey I. Zink;Fuyuhiko Tamanoi

  • Biocompatibility, Biodistribution, and Drug-Delivery Efficiency of Mesoporous Silica Nanoparticles for Cancer Therapy in Animals

    Jie Lu;Monty Liong;Zongxi Li;Jeffrey I. Zink

  • The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae

    Gangfeng Xu;Boris Lin;Kazuma Tanaka;Diane Dunn

  • Autonomous in vitro anticancer drug release from mesoporous silica nanoparticles by pH-sensitive nanovalves.

    Huan Meng;Min Xue;Tian Xia;Yan Li Zhao

  • Light‐Activated Nanoimpeller‐Controlled Drug Release in Cancer Cells

    Jie Lu;Eunshil Choi;Fuyuhiko Tamanoi;Jeffrey I. Zink

  • Spatial regulation of the exocyst complex by Rho1 GTPase

    Wei Guo;Wei Guo;Fuyuhiko Tamanoi;Peter Novick

  • IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein.

    K Tanaka;M Nakafuku;F Tamanoi;Y Kaziro

  • Differential activation of yeast adenylate cyclase by wild type and mutant RAS proteins

    Daniel Broek;Nasrollah Samiy;Ottavio Fasano;Asao Fujiyama

  • A tagging-via-substrate technology for detection and proteomics of farnesylated proteins

    Yoonjung Kho;Sung Chan Kim;Chen Jiang;Deb Barma

  • Identification of Ras farnesyltransferase inhibitors by microbial screening.

    Mitsunobu Hara;Kazuhito Akasaka;Shiro Akinaga;Masami Okabe

  • Analysis of the transforming potential of the human H-ras gene by random mutagenesis.

    Ottavio Fasano;Thomas Aldrich;Fuyuhiko Tamanoi;Elizabeth Taparowsky

  • Quantitative 3D imaging of whole, unstained cells by using X-ray diffraction microscopy.

    Huaidong Jiang;Changyong Song;Chien-Chun Chen;Rui Xu

  • Loss of the TOR Kinase Tor2 Mimics Nitrogen Starvation and Activates the Sexual Development Pathway in Fission Yeast

    Tomohiko Matsuo;Yoko Otsubo;Jun Urano;Fuyuhiko Tamanoi

  • Rho3 of Saccharomyces cerevisiae, which regulates the actin cytoskeleton and exocytosis, is a GTPase which interacts with Myo2 and Exo70.

    Nicole G. G. Robinson;Lea Guo;Jun Imai;Akio Toh-e

  • Specific activation of mTORC1 by RHEB G-protein in vitro involves enhanced recruitment of its substrate protein

    Tatsuhiro Sato;Akio Nakashima;Lea Guo;Fuyuhiko Tamanoi

  • Development of mesoporous silica-based nanoparticles with controlled release capability for cancer therapy

    Harutaka Mekaru;Jie Lu;Fuyuhiko Tamanoi

  • Single amino-acid changes that confer constitutive activation of mTOR are discovered in human cancer

    T Sato;A Nakashima;L Guo;K Coffman

  • Mesoporous Silica Nanoparticles Facilitate Delivery of siRNA to Shutdown Signaling Pathways in Mammalian Cells

    Christopher Hom;Jie Lu;Monty Liong;Hanzhi Luo

  • The Rheb family of GTP-binding proteins

    Paul-Joseph Aspuria;Fuyuhiko Tamanoi

Frequent Co-Authors

Jeffrey I. Zink
Jeffrey I. Zink University of California, Los Angeles
Bruce Stillman
Bruce Stillman Cold Spring Harbor Laboratory
Andre E. Nel
Andre E. Nel University of California, Los Angeles
Ohyun Kwon
Ohyun Kwon University of California, Los Angeles
Charles C. Richardson
Charles C. Richardson Harvard University
Tian Xia
Tian Xia University of California, Los Angeles
Michael H. Gelb
Michael H. Gelb University of Washington
Channing J. Der
Channing J. Der University of North Carolina at Chapel Hill
Niveen M. Khashab
Niveen M. Khashab King Abdullah University of Science and Technology
J. Fraser Stoddart
J. Fraser Stoddart Northwestern University

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