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Biology and Biochemistry
Australia
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
81
Citations
31402
World Ranking
3812
National Ranking
90

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Australia Leader Award

Overview

Michael J. Rogers is affiliated with the Garvan Institute of Medical Research in Australia. Their work is primarily situated in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a particular focus on Molecular Biology among related subfields.

Their research topics cover a range of areas including:

  • Plant biochemistry and biosynthesis
  • Bone health and treatments
  • Bone Metabolism and Diseases
  • Biomarkers in Disease Mechanisms
  • Inflammasome and immune disorders
  • Interferon and immune responses
  • Adipokines, Inflammation, and Metabolic Diseases

Michael J. Rogers has contributed to several scientific publications. Notable recent papers include:

  • "Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption," published in 2021 in Cell
  • "Molecular mechanisms of action of bisphosphonates and new insights into their effects outside the skeleton," published in 2020 in Bone
  • "Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption," published in 2021 in Cell
  • "Oxysterols: From physiological tuners to pharmacological opportunities," published in 2020 in British Journal of Pharmacology
  • "Single cell multi-omics characterise discrete human tendon cells populations that persist in vitro and on fibrous scaffolds," published in 2022 in European Cells and Materials

Their frequent co-authors include:

  • Séan O'Donoghue
  • Marcia A. Munoz
  • Tri Giang Phan
  • Robert Brink
  • Oliver P. Skinner

Michael J. Rogers's work has appeared in various publication venues, with recurring contributions to:

  • Zenodo (CERN European Organization for Nuclear Research)
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell
  • Harvard Dataverse
  • Bone

Best Publications

  • Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy

    R. G. G. Russell;N. B. Watts;F. H. Ebetino;M. J. Rogers

  • Nitrogen-Containing Bisphosphonates Inhibit the Mevalonate Pathway and Prevent Post-Translational Prenylation of GTP-Binding Proteins, Including Ras

    Steven P. Luckman;Steven P. Luckman;David E. Hughes;Fraser P. Coxon;Fraser P. Coxon;R. Graham G. Russell

  • Structure-Activity Relationships for Inhibition of Farnesyl Diphosphate Synthase in Vitro and Inhibition of Bone Resorption in Vivo by Nitrogen-Containing Bisphosphonates

    James Edward Dunford;Keith Thompson;Fraser Coxon;S. P. Luckman

  • Cellular and molecular mechanisms of action of bisphosphonates

    M J Rogers;Sharon Andrea Gordon;H L Benford;Fraser Coxon

  • Bisphosphonates: from the laboratory to the clinic and back again.

    R.G.G Russell;M.J Rogers

  • Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro

    J. E. Fisher;M. J. Rogers;J. M. Halasy;S. P. Luckman

  • New insights into the molecular mechanisms of action of bisphosphonates.

    Michael John Rogers

  • Biochemical and molecular mechanisms of action of bisphosphonates

    Michael J. Rogers;Julie C. Crockett;Fraser P. Coxon;Jukka Mönkkönen

  • Molecular mechanisms of action of bisphosphonates: current status.

    Anke Jozefien Roelofs;Keith Thompson;Sharon Andrea Gordon;Michael John Rogers

  • The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs.

    K. L. Kavanagh;K. Guo;James Edward Dunford;James Edward Dunford;James Edward Dunford;X. Wu

  • Bone remodelling at a glance

    Julie C. Crockett;Michael J. Rogers;Fraser P. Coxon;Lynne J. Hocking

  • Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5'-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro.

    Julie C. Frith;Jukka Mönkkönen;G. Michael Blackburn;R. Graham G. Russell

  • Molecular mechanisms of action of bisphosphonates.

    M.J Rogers;J.C Frith;J.C Frith;S.P Luckman;S.P Luckman;F.P Coxon;F.P Coxon

  • Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti-tumour activity.

    C M Shipman;Michael John Rogers;J F Apperley;R G Russell

  • Bisphosphonates: an update on mechanisms of action and how these relate to clinical efficacy.

    R. G. G. Russell;Z. Xia;J. E. Dunford;U. Oppermann

  • Protein geranylgeranylation is required for osteoclast formation, function, and survival: inhibition by bisphosphonates and GGTI-298.

    Fraser P. Coxon;Miep H. Helfrich;Robert Van't Hof;Saïd Sebti

  • Further Insight into Mechanism of Action of Clodronate: Inhibition of Mitochondrial ADP/ATP Translocase by a Nonhydrolyzable, Adenine-Containing Metabolite

    Petri P. Lehenkari;Maarit Kellinsalmi;Juha P. Näpänkangas;Kari V. Ylitalo

  • Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL

    Cristina Sobacchi;Annalisa Frattini;Matteo M Guerrini;Mario Abinun

  • Identification of a Novel Phosphonocarboxylate Inhibitor of Rab Geranylgeranyl Transferase That Specifically Prevents Rab Prenylation in Osteoclasts and Macrophages

    Fraser P. Coxon;Miep H. Helfrich;Banafshe Larijani;Mariusz Muzylak

  • Heterocycle‐Containing Bisphosphonates Cause Apoptosis and Inhibit Bone Resorption by Preventing Protein Prenylation: Evidence from Structure‐Activity Relationships in J774 Macrophages

    Steven P. Luckman;Steven P. Luckman;Fraser P. Coxon;Fraser P. Coxon;Frank H. Ebetino;R. Graham G. Russell

Frequent Co-Authors

R. G. G. Russell
R. G. G. Russell University of Sheffield
Tri Giang Phan
Tri Giang Phan Garvan Institute of Medical Research
Udo Oppermann
Udo Oppermann University of Oxford
Miguel C. Seabra
Miguel C. Seabra Universidade Nova de Lisboa
Seppo Auriola
Seppo Auriola University of Eastern Finland
Wolfgang Weninger
Wolfgang Weninger Medical University of Vienna
Karen P. Steel
Karen P. Steel King's College London
Robert Brink
Robert Brink University of New South Wales
Ettore Appella
Ettore Appella National Institutes of Health
Dominique Heymann
Dominique Heymann University of Nantes

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