D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics D-index 75 Citations 21,323 203 World Ranking 1239 National Ranking 176

Research.com Recognitions

Awards & Achievements

2020 - Fellow of the American Academy of Arts and Sciences

2009 - Fellow of the Royal Society, United Kingdom

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Mutation
  • Genetics

Karen P. Steel mainly investigates Genetics, Mutant, Cell biology, Gene and Inner ear. Her Genetics research includes themes of Molecular biology and Hearing loss. In most of her Mutant studies, her work intersects topics such as Mutation.

Her Cell biology research incorporates themes from Hair cell and Organ of Corti. The concepts of her Gene study are interwoven with issues in Evolutionary biology and Sexual dimorphism. Inner ear is a primary field of her research addressed under Anatomy.

Her most cited work include:

  • A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. (599 citations)
  • A type VII myosin encoded by the mouse deafness gene shaker-1. (584 citations)
  • Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. (493 citations)

What are the main themes of her work throughout her whole career to date?

Karen P. Steel mainly focuses on Genetics, Mutant, Gene, Cell biology and Inner ear. As part of her studies on Genetics, Karen P. Steel often connects relevant subjects like Hearing loss. The study incorporates disciplines such as Molecular biology, Allele and Missense mutation in addition to Mutant.

Her work investigates the relationship between Cell biology and topics such as Hair cell that intersect with problems in Heterozygote advantage. Her Inner ear study integrates concerns from other disciplines, such as Cochlea and Pathology. Karen P. Steel combines subjects such as Inner ear morphogenesis and Exon with her study of Mutation.

She most often published in these fields:

  • Genetics (61.76%)
  • Mutant (40.76%)
  • Gene (35.29%)

What were the highlights of her more recent work (between 2012-2021)?

  • Genetics (61.76%)
  • Gene (35.29%)
  • Hearing loss (31.93%)

In recent papers she was focusing on the following fields of study:

Her primary areas of investigation include Genetics, Gene, Hearing loss, Phenotype and Hair cell. She interconnects Exome sequencing, Genetic heterogeneity and Internal medicine in the investigation of issues within Hearing loss. Her Phenotype research is multidisciplinary, incorporating elements of Quantitative trait locus, Genotype and Sexual dimorphism.

Karen P. Steel has researched Hair cell in several fields, including Organ of Corti and Cell biology. Her Mutant study also includes fields such as

  • Mutation which intersects with area such as Disease,
  • Molecular biology, which have a strong connection to Sonic hedgehog. The subject of her Inner ear research is within the realm of Anatomy.

Between 2012 and 2021, her most popular works were:

  • Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes (348 citations)
  • A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains (266 citations)
  • Prevalence of sexual dimorphism in mammalian phenotypic traits. (115 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Mutation
  • Genetics

Gene, Genetics, Phenotype, Hearing loss and Mutant are her primary areas of study. Many of her research projects under Genetics are closely connected to Retinopathy with Retinopathy, tying the diverse disciplines of science together. Her Phenotype study incorporates themes from Genome-wide association study, Allele and Sexual dimorphism.

The Hearing loss study combines topics in areas such as Endocochlear potential, Inner ear, Organ of Corti and Genetic heterogeneity. Her Inner ear study combines topics in areas such as SOX2, Penetrance and Ectopic expression. Her Mutant research is multidisciplinary, relying on both Evolutionary biology, Sex characteristics, Phenotypic trait, Quantitative trait locus and Genotype.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A type VII myosin encoded by the mouse deafness gene shaker-1.

F. Gibson;J. Walsh;P. Mburu;A. Varela.
Nature (1995)

747 Citations

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.

P M Nolan;J Peters;M Strivens;D Rogers.
Nature Genetics (2000)

726 Citations

Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse.

John A. Curtin;Elizabeth Quint;Vicky Tsipouri;Ruth M. Arkell.
Current Biology (2003)

671 Citations

Mutations in the seed region of human miR-96 are responsible for nonsyndromic progressive hearing loss.

Ángeles Mencía;Silvia Modamio-Høybjør;Nick Redshaw;Matías Morín.
Nature Genetics (2009)

599 Citations

The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells

Karen B. Avraham;Tama Hasson;Karen P. Steel;David M. Kingsley.
Nature Genetics (1995)

565 Citations

TRP-2/DT, a new early melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor.

Karen P Steel;Duncan R. Davidson;Ian Jackson.
Development (1992)

562 Citations

Sox2 is required for sensory organ development in the mammalian inner ear

Amy E. Kiernan;Anna L. Pelling;Keith K. H. Leung;Anna S. P. Tang.
Nature (2005)

545 Citations

Wnt5a functions in planar cell polarity regulation in mice

Dong Qian;Chonnettia Jones;Agnieszka Rzadzinska;Sharayne Mark.
Developmental Biology (2007)

541 Citations

Another role for melanocytes: their importance for normal stria vascularis development in the mammalian inner ear.

K.P. Steel;C. Barkway.
Development (1989)

509 Citations

Mutations in Cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for Usher syndrome type 1D.

Federica Di Palma;Ralph H. Holme;Elizabeth C. Bryda;Inna A. Belyantseva.
Nature Genetics (2001)

492 Citations

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