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Genetics

D-Index
65
Citations
14955
World Ranking
2702
National Ranking
1187

Overview

Andrew J. Griffith is a researcher affiliated with the National Institutes of Health in the United States, with a primary focus on the intersections of neuroscience, biochemistry, genetics, and molecular biology. Their work spans multiple disciplines, including sensory systems, molecular biology, neurology, otorhinolaryngology, and genetics, reflecting a broad scope within biomedical research.

Their research emphasizes topics related to hearing and auditory function such as hearing, cochlea, tinnitus, and genetics, as well as vestibular and auditory disorders, ear surgery, otitis media, hearing loss, rehabilitation, genomics, rare diseases, cellular transport, secretion, and genomic variations including chromosomal abnormalities.

Andrew J. Griffith has recent papers that cover various aspects of genetic hearing loss, auditory disorders, and related molecular genetics. These include:

  • "Genetic architecture and phenotypic landscape of SLC26A4-related hearing loss," 2021, published in Human Genetics
  • "Genetic Hearing Loss Associated With Autoinflammation," 2020, published in Frontiers in Neurology
  • "Disease-specific ACMG/AMP guidelines improve sequence variant interpretation for hearing loss," 2021, published in Genetics in Medicine
  • "Atypical and ultra-rare Usher syndrome: a review," 2020, published in Ophthalmic Genetics
  • "Vestibular phenotype-genotype correlation in a cohort of 90 patients with Usher syndrome," 2020, published in Clinical Genetics

Their collaborations include frequent co-authorship with Isabelle Roux, Thomas B. Friedman, Keiji Honda, Carmen C. Brewer, and Robert J. Morell. These partnerships highlight a network of researchers with a shared focus on genetic and auditory disorders.

Among the key publication venues where Andrew J. Griffith has contributed multiple articles are:

  • Human Genetics
  • Genetics in Medicine
  • Clinical Genetics
  • Journal of the Association for Research in Otolaryngology
  • bioRxiv (Cold Spring Harbor Laboratory)

Their work is positioned within major fields such as neuroscience and biochemistry, genetics, and molecular biology, with a notable emphasis on sensory systems and genetics-related subfields.

Best Publications

  • Usher Syndrome 1D and Nonsyndromic Autosomal Recessive Deafness DFNB12 Are Caused by Allelic Mutations of the Novel Cadherin-Like Gene CDH23

    Julie M. Bork;Linda M. Peters;Saima Riazuddin;Saima Riazuddin;Steve L. Bernstein

  • Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29.

    Edward R Wilcox;Quianna L Burton;Sadaf Naz;Saima Riazuddin;Saima Riazuddin

  • Dominant and recessive deafness caused by mutations of a novel gene, TMC1 , required for cochlear hair-cell function

    Kiyoto Kurima;Linda M. Peters;Yandan Yang;Saima Riazuddin

  • Mutations of the protocadherin gene PCDH15 cause Usher syndrome type 1F.

    Zubair M. Ahmed;Saima Riazuddin;Steve L. Bernstein;Zahoor Ahmed

  • Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes

    Yoshiyuki Kawashima;Gwenaëlle S.G. Géléoc;Gwenaëlle S.G. Géléoc;Kiyoto Kurima;Valentina Labay;Valentina Labay

  • TMC1 and TMC2 are components of the mechanotransduction channel in hair cells of the mammalian inner ear.

    Bifeng Pan;Gwenaelle S. Géléoc;Yukako Asai;Geoffrey C. Horwitz

  • Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks.

    P R Blier;A J Griffith;J Craft;J A Hardin

  • Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia.

    Inna A. Belyantseva;Erich T. Boger;Erich T. Boger;Sadaf Naz;Gregory I. Frolenkov

  • Origins and frequencies of SLC26A4 (PDS) mutations in east and south Asians: global implications for the epidemiology of deafness

    Park Hj;Shaukat S;Liu Xz;Hahn Sh

  • Expert specification of the ACMG/AMP variant interpretation guidelines for genetic hearing loss.

    Andrea M Oza;Andrea M Oza;Marina T DiStefano;Marina T DiStefano;Sarah E Hemphill;Brandon J Cushman

  • SLC26A4/PDS genotype-phenotype correlation in hearing loss with enlargement of the vestibular aqueduct (EVA): evidence that Pendred syndrome and non-syndromic EVA are distinct clinical and genetic entities

    S P Pryor;A C Madeo;J C Reynolds;N J Sarlis

  • PCDH15 is expressed in the neurosensory epithelium of the eye and ear and mutant alleles are responsible for both USH1F and DFNB23

    Zubair M. Ahmed;Saima Riazuddin;Jamil Ahmad;Steve L. Bernstein

  • The Tip-Link Antigen, a Protein Associated with the Transduction Complex of Sensory Hair Cells, Is Protocadherin-15

    Zubair M. Ahmed;Richard Goodyear;Saima Riazuddin;Ayala Lagziel

  • Mutations in COL11A2 cause non-syndromic hearing loss (DFNA13).

    W. T. Mcguirt;S. D. Prasad;A. J. Griffith;H. P. M. Kunst

  • Human Nonsyndromic Sensorineural Deafness

    Thomas B. Friedman;Andrew J. Griffith

  • Genetic insights into the morphogenesis of inner ear hair cells

    Gregory I Frolenkov;Inna A Belyantseva;Thomas B Friedman;Andrew J Griffith

  • Beethoven, a mouse model for dominant, progressive hearing loss DFNA36.

    Sarah Vreugde;Alexandra Erven;Corné J. Kros;Walter Marcotti

  • Mutations of MYO6 Are Associated with Recessive Deafness, DFNB37

    Zubair M. Ahmed;Robert J. Morell;Saima Riazuddin;Andrea Gropman

  • Actin-Bundling Protein TRIOBP Forms Resilient Rootlets of Hair Cell Stereocilia Essential for Hearing

    Shin Ichiro Kitajiri;Takeshi Sakamoto;Inna A. Belyantseva;Richard J. Goodyear

  • Modification of Human Hearing Loss by Plasma-Membrane Calcium Pump PMCA2

    Julie M. Schultz;Yandan Yang;Ariel J. Caride;Adelaida G. Filoteo

Frequent Co-Authors

Thomas B. Friedman
Thomas B. Friedman National Institutes of Health
Saima Riazuddin
Saima Riazuddin University of Maryland, Baltimore
Zubair M. Ahmed
Zubair M. Ahmed University of Maryland, Baltimore
Robert J. Morell
Robert J. Morell National Institutes of Health
Sheikh Riazuddin
Sheikh Riazuddin University of Health Sciences Lahore
Inna A. Belyantseva
Inna A. Belyantseva National Institutes of Health
Jeffrey R. Holt
Jeffrey R. Holt Boston Children's Hospital
Seth L. Alper
Seth L. Alper Beth Israel Deaconess Medical Center
Shaheen N. Khan
Shaheen N. Khan University of the Punjab
Karen B. Avraham
Karen B. Avraham Tel Aviv University

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