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Konstanze Döhner

Konstanze Döhner

D-Index & Metrics

Medicine

D-Index
115
Citations
60789
World Ranking
4470
National Ranking
243

Overview

Konstanze Döhner is affiliated with the University of Ulm in Germany and focuses research primarily on hematology within the broader fields of medicine and biochemistry, genetics, and molecular biology. Their work comprises a significant contribution to understanding and treating various blood cancers, particularly acute myeloid leukemia (AML).

The scientist has authored numerous papers focused notably on acute myeloid leukemia research, reflecting one of the main topics covered in their scholarship. Other prominent research themes include myeloproliferative neoplasms diagnosis and treatment, chronic myeloid leukemia treatments, cancer genomics and diagnostics, along with studies on histone deacetylase inhibitors and protein degradation and inhibitors.

Key recent publications include:

  • 2021 Update on MRD in acute myeloid leukemia: a consensus document from the European LeukemiaNet MRD Working Party, 2021, Blood
  • Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia, 2020, Science
  • Unified classification and risk-stratification in Acute Myeloid Leukemia, 2022, Nature Communications
  • Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin, 2021, Blood
  • Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial, 2020, Blood

Their collaborations often include frequent coauthors such as Hartmut Döhner, Michael Heuser, Lars Bullinger, Arnold Ganser, and Felicitas Thol, with frequent joint publications highlighting extensive teamwork in the field of hematologic malignancies.

Konstanze Döhner's work has been published extensively in specialized journals, with the top venues including Blood, HemaSphere, Leukemia, Blood Advances, and Haematologica. Blood represents the most common publication forum, reflecting a concentrated engagement with this key hematology platform.

Their main fields of study reflect a research orientation toward:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

The subfields of study further clarify their specialization:

  • Hematology
  • Molecular Biology
  • Genetics
  • Cancer Research
  • Public Health, Environmental and Occupational Health

Major research topics explored in their work include:

  • Acute Myeloid Leukemia Research
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Chronic Myeloid Leukemia Treatments
  • Cancer Genomics and Diagnostics
  • Acute Lymphoblastic Leukemia research
  • Histone Deacetylase Inhibitors Research
  • Protein Degradation and Inhibitors

Best Publications

  • Genomic Aberrations and Survival in Chronic Lymphocytic Leukemia

    Hartmut Döhner;Stephan Stilgenbauer;Axel Benner;Elke Leupolt

  • Genomic Classification and Prognosis in Acute Myeloid Leukemia

    Elli Papaemmanuil;Moritz Gerstung;Lars Bullinger;Verena I Gaidzik

  • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.

    Ross L. Levine;Ross L. Levine;Martha Wadleigh;Jan Cools;Benjamin L. Ebert;Benjamin L. Ebert

  • Mutations and Treatment Outcome in Cytogenetically Normal Acute Myeloid Leukemia

    Richard F. Schlenk;Konstanze Döhner;Jürgen Krauter;Stefan Fröhling

  • Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation

    Richard M. Stone;Sumithra J. Mandrekar;Ben L. Sanford;Kristina Laumann

  • Retinoic acid and arsenic trioxide for acute promyelocytic leukemia

    F. Lo-Coco;G. Avvisati;M. Vignetti;C. Thiede

  • Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia.

    Lars Bullinger;Konstanze Döhner;Eric Bair;Stefan Fröhling

  • Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm.

    Stefan Fröhling;Richard F. Schlenk;Jochen Breitruck;Axel Benner

  • Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations.

    Konstanze Döhner;Richard F Schlenk;Marianne Habdank;Claudia Scholl

  • IDH1 and IDH2 Mutations Are Frequent Genetic Alterations in Acute Myeloid Leukemia and Confer Adverse Prognosis in Cytogenetically Normal Acute Myeloid Leukemia With NPM1 Mutation Without FLT3 Internal Tandem Duplication

    Peter Paschka;Richard F. Schlenk;Verena I. Gaidzik;Marianne Habdank

  • Minimal/measurable residual disease in AML: a consensus document from the European LeukemiaNet MRD Working Party.

    Gerrit J. Schuurhuis;Michael Heuser;Sylvie Freeman;Marie Christine Béne

  • Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

    Tobias Rausch;David T.W. Jones;Marc Zapatka;Adrian M. Stütz

  • A Single Oncogenic Enhancer Rearrangement Causes Concomitant EVI1 and GATA2 Deregulation in Leukemia

    Stefan Gröschel;Stefan Gröschel;Mathijs A Sanders;Remco Hoogenboezem;Elzo de Wit

  • TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome.

    Frank G. Rücker;Richard F. Schlenk;Lars Bullinger;Sabine Kayser

  • Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells.

    Claudia Scholl;Stefan Fröhling;Ian F. Dunn;Anna C. Schinzel

  • CEBPA Mutations in Younger Adults With Acute Myeloid Leukemia and Normal Cytogenetics: Prognostic Relevance and Analysis of Cooperating Mutations

    Stefan Fröhling;Richard F. Schlenk;Ina Stolze;Jörg Bihlmayr

  • Effect of Mutation Order on Myeloproliferative Neoplasms

    Christina A. Ortmann;David G. Kent;Jyoti Nangalia;Yvonne Silber

  • Gene mutations and treatment outcome in chronic lymphocytic leukemia: Results from the CLL8 trial

    Stephan Stilgenbauer;Andrea Schnaiter;Peter Paschka;Thorsten Zenz;Thorsten Zenz

  • Genomics of Acute Myeloid Leukemia Diagnosis and Pathways

    Lars Bullinger;Konstanze Döhner;Hartmut Döhner

  • The impact of therapy-related acute myeloid leukemia (AML) on outcome in 2853 adult patients with newly diagnosed AML.

    Sabine Kayser;Konstanze Döhner;Jürgen Krauter;Claus Henning Köhne

Frequent Co-Authors

Hartmut Döhner
Hartmut Döhner University of Ulm
Richard F. Schlenk
Richard F. Schlenk University Hospital Heidelberg
Lars Bullinger
Lars Bullinger Charité - University Medicine Berlin
Arnold Ganser
Arnold Ganser Hannover Medical School
Michael Heuser
Michael Heuser Hannover Medical School
Michael Lübbert
Michael Lübbert University of Freiburg
Brigitte Schlegelberger
Brigitte Schlegelberger Hannover Medical School
Axel Benner
Axel Benner German Cancer Research Center
Gudrun Göhring
Gudrun Göhring Hannover Medical School

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