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Brigitte Schlegelberger

Brigitte Schlegelberger

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Biology and Biochemistry
Germany
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
110
Citations
42287
World Ranking
972
National Ranking
64

Medicine

D-Index
110
Citations
42327
World Ranking
5589
National Ranking
309

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Germany Leader Award
  • 2025 - Research.com Biology and Biochemistry in Germany Leader Award

Overview

Brigitte Schlegelberger is affiliated with Hannover Medical School in Germany and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research primarily focuses on hematology, genetics, molecular biology, and aspects of public health, environmental, and occupational health.

The scientist's work covers several main topics including:

  • Acute Myeloid Leukemia Research
  • Acute Lymphoblastic Leukemia Research
  • Chronic Myeloid Leukemia Treatments
  • Cancer Genomics and Diagnostics
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Chronic Lymphocytic Leukemia Research
  • Childhood Cancer Survivors' Quality of Life

Frequent publication venues for Schlegelberger include:

  • Blood
  • Leukemia
  • Genes Chromosomes and Cancer
  • Medizinische Genetik
  • Cancers

Notable recent papers authored or co-authored by Schlegelberger include:

  • "Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes" (2021, Nature Medicine)
  • "The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants" (2020, Nature Communications)
  • "Dihydropyrimidine Dehydrogenase Testing prior to Treatment with 5-Fluorouracil, Capecitabine, and Tegafur: A Consensus Paper" (2020, Oncology Research and Treatment)
  • "High-risk additional chromosomal abnormalities at low blast counts herald death by CML" (2020, Leukemia)
  • "Guiding the global evolution of cytogenetic testing for hematologic malignancies" (2022, Blood)

Schlegelberger has collaborated frequently with several co-authors, among whom are:

  • Gudrun Göhring
  • Doris Steinemann
  • Anke K. Bergmann
  • Gunnar Cario
  • Yvonne Lisa Behrens

Their scientific contributions cover a substantial body of work in acute leukemia research and cytogenetics, with a focus on understanding genetic abnormalities and their clinical implications. Their studies contribute to both the molecular understanding and clinical management of hematologic malignancies.

Best Publications

  • Mutations and Treatment Outcome in Cytogenetically Normal Acute Myeloid Leukemia

    Richard F. Schlenk;Konstanze Döhner;Jürgen Krauter;Stefan Fröhling

  • Oncogene-induced senescence as an initial barrier in lymphoma development

    Melanie Braig;Soyoung Lee;Christoph Loddenkemper;Cornelia Rudolph

  • Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease

    Stefan Stein;Marion G. Ott;Stephan Schultze-Strasser;Anna Jauch

  • A physical map of the human genome.

    John Douglas Mcpherson;Marco Marra;Marco Marra;La Deana Hillier;Robert H. Waterston

  • TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome.

    Frank G. Rücker;Richard F. Schlenk;Lars Bullinger;Sabine Kayser

  • Gene Therapy for Wiskott-Aldrich Syndrome—Long-Term Efficacy and Genotoxicity

    Christian Jörg Braun;Kaan Boztug;Anna Paruzynski;Maximilian Witzel

  • TP53 Mutations in Low-Risk Myelodysplastic Syndromes With del(5q) Predict Disease Progression

    Martin Jädersten;Leonie Saft;Alexander Smith;Austin Kulasekararaj

  • A randomized phase 3 study of lenalidomide versus placebo in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with del5q

    Pierre Fenaux;Aristoteles Giagounidis;Dominik Selleslag;Odile Beyne-Rauzy

  • Frequency and prognostic impact of mutations in SRSF2, U2AF1, and ZRSR2 in patients with myelodysplastic syndromes

    Felicitas Thol;Sofia Kade;Carola Schlarmann;Patrick Löffeld

  • Incidence and Prognostic Influence of DNMT3A Mutations in Acute Myeloid Leukemia

    Felicitas Thol;Frederik Damm;Andrea Lüdeking;Claudia Winschel

  • The impact of therapy-related acute myeloid leukemia (AML) on outcome in 2853 adult patients with newly diagnosed AML.

    Sabine Kayser;Konstanze Döhner;Jürgen Krauter;Claus Henning Köhne

  • Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32).

    Quangeng Zhang;Reiner Siebert;Minhong Yan;Bernd Hinzmann

  • Monitoring of Minimal Residual Disease in NPM1-Mutated Acute Myeloid Leukemia: A Study From the German-Austrian Acute Myeloid Leukemia Study Group

    Jan Krönke;Richard F. Schlenk;Kai-Ole Jensen;Florian Tschürtz

  • Tolerability-Adapted Imatinib 800 mg/d Versus 400 mg/d Versus 400 mg/d Plus Interferon-α in Newly Diagnosed Chronic Myeloid Leukemia

    Rüdiger Hehlmann;Michael Lauseker;Susanne Jung-Munkwitz;Armin Leitner

  • RUNX1 Mutations in Acute Myeloid Leukemia: Results From a Comprehensive Genetic and Clinical Analysis From the AML Study Group

    Verena I. Gaidzik;Lars Bullinger;Richard F. Schlenk;Andreas S. Zimmermann

  • MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3)

    Olatoyosi M. Sobulo;Julian Borrow;Ronald Tomek;Shalini Reshmi

  • Prevalence, clinical characteristics, and prognosis of GATA2-related myelodysplastic syndromes in children and adolescents.

    Marcin W. Wlodarski;Marcin W. Wlodarski;Shinsuke Hirabayashi;Victor Pastor;Jan Starý

  • Breast carcinoma during pregnancy. International recommendations from an expert meeting.

    Sibylle Loibl;Gunter von Minckwitz;Karin Gwyn;Paul Ellis

  • Clonal Dominance of Hematopoietic Stem Cells Triggered by Retroviral Gene Marking

    Olga Kustikova;Boris Fehse;Ute Modlich;Min Yang

  • The BCL11 gene family: involvement of BCL11A in lymphoid malignancies.

    Ed Satterwhite;Takashi Sonoki;Tony G. Willis;Lana Harder

Frequent Co-Authors

Gudrun Göhring
Gudrun Göhring Hannover Medical School
Arnold Ganser
Arnold Ganser Hannover Medical School
Doris Steinemann
Doris Steinemann Hannover Medical School
Michael Heuser
Michael Heuser Hannover Medical School
Konstanze Döhner
Konstanze Döhner University of Ulm
Hans Kreipe
Hans Kreipe Hannover Medical School
Hartmut Döhner
Hartmut Döhner University of Ulm
Richard F. Schlenk
Richard F. Schlenk University Hospital Heidelberg
Christopher Baum
Christopher Baum Charité - University Medicine Berlin
Charlotte M. Niemeyer
Charlotte M. Niemeyer University of Freiburg

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