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Medicine

D-Index
117
Citations
52437
World Ranking
4203
National Ranking
229

Overview

Axel Benner is affiliated with the German Cancer Research Center in Germany and has contributed extensively to medical research, particularly in hematology, molecular biology, and oncology. Their publication record comprises 254 works in medicine and 83 publications in biochemistry, genetics, and molecular biology.

Their subfields of research include hematology with 93 publications, molecular biology with 60, oncology with 49, pulmonary and respiratory medicine with 32, and genetics with 28. The primary research topics that Axel Benner focuses on include:

  • Acute Myeloid Leukemia Research
  • Multiple Myeloma Research and Treatments
  • Protein Degradation and Inhibitors
  • Cancer Genomics and Diagnostics
  • Chronic Lymphocytic Leukemia Research
  • Acute Lymphoblastic Leukemia Research
  • Hematopoietic Stem Cell Transplantation

Axel Benner frequently publishes in prominent scientific journals. The most common publication venues are Blood with 33 publications, Leukemia with 12, HemaSphere with 5, Journal of Clinical Oncology with 4, and International Journal of Cancer also with 4.

Some of their recent papers include:

  • "Machine learning workflows to estimate class probabilities for precision cancer diagnostics on DNA methylation microarray data" (2020, Nature Protocols)
  • "The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution" (2020, Nature Communications)
  • "Isatuximab, Carfilzomib, Lenalidomide, and Dexamethasone for the Treatment of High-Risk Newly Diagnosed Multiple Myeloma" (2023, Journal of Clinical Oncology)
  • "Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial" (2020, Blood)
  • "Daratumumab for systemic AL amyloidosis: prognostic factors and adverse outcome with nephrotic-range albuminuria" (2020, Blood)

Frequent co-authors collaborating with Axel Benner include:

  • Hartmut Döhner
  • Hartmut Goldschmidt
  • Konstanze Döhner
  • Lars Bullinger
  • Hans Salwender

The scope of Axel Benner's research portfolio reflects a significant focus on leukemia and myeloma, incorporating molecular diagnostic techniques and treatment evaluation. Their contributions span across clinical oncology and biomedical research, supporting advancements in understanding cancer pathology and therapeutic strategies.

Best Publications

  • Genomic Aberrations and Survival in Chronic Lymphocytic Leukemia

    Hartmut Döhner;Stephan Stilgenbauer;Axel Benner;Elke Leupolt

  • DNA methylation-based classification of central nervous system tumours

    David Capper;David Capper;David Capper;David T. W. Jones;Martin Sill;Volker Hovestadt

  • Mutations and Treatment Outcome in Cytogenetically Normal Acute Myeloid Leukemia

    Richard F. Schlenk;Konstanze Döhner;Jürgen Krauter;Stefan Fröhling

  • Matrix‐based comparative genomic hybridization: Biochips to screen for genomic imbalances

    Sabina Solinas-Toldo;Stefan Lampel;Stephan Stilgenbauer;Jeremy Nickolenko

  • Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm.

    Stefan Fröhling;Richard F. Schlenk;Jochen Breitruck;Axel Benner

  • p53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-cell leukemias.

    Hartmut Döhner;Konstanze Fischer;Martin Bentz;Katrin Hansen

  • p16INK4a immunohistochemistry improves interobserver agreement in the diagnosis of cervical intraepithelial neoplasia.

    Rüdiger Klaes;Axel Benner;Tibor Friedrich;Rüdiger Ridder

  • CEBPA Mutations in Younger Adults With Acute Myeloid Leukemia and Normal Cytogenetics: Prognostic Relevance and Analysis of Cooperating Mutations

    Stefan Fröhling;Richard F. Schlenk;Ina Stolze;Jörg Bihlmayr

  • 11q Deletions Identify a New Subset of B-Cell Chronic Lymphocytic Leukemia Characterized by Extensive Nodal Involvement and Inferior Prognosis

    Hartmut Döhner;Stephan Stilgenbauer;Michael R. James;Axel Benner

  • Delineation of Two Clinically and Molecularly Distinct Subgroups of Posterior Fossa Ependymoma

    Hendrik Witt;Stephen C. Mack;Marina Ryzhova;Sebastian Bender;Sebastian Bender

  • Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up.

    Thorsten Zenz;Alexander Kröber;Katrin Scherer;Sonja Häbe

  • Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients.

    Niels Halama;Niels Halama;Inka Zoernig;Anna Berthel;Christoph Kahlert

  • Localization and Density of Immune Cells in the Invasive Margin of Human Colorectal Cancer Liver Metastases Are Prognostic for Response to Chemotherapy

    Niels Halama;Sara Michel;Matthias Kloor;Inka Zoernig

  • Individual Patient Data–Based Meta-Analysis of Patients Aged 16 to 60 Years With Core Binding Factor Acute Myeloid Leukemia: A Survey of the German Acute Myeloid Leukemia Intergroup

    RF Schlenk;A Benner;J Krauter;T Buchner

  • Prognostic Significance of Partial Tandem Duplications of the MLL Gene in Adult Patients 16 to 60 Years Old With Acute Myeloid Leukemia and Normal Cytogenetics: A Study of the Acute Myeloid Leukemia Study Group Ulm

    Konstanze Döhner;Karen Tobis;Regina Ulrich;Stefan Fröhling

  • Differential impact of allelic ratio and insertion site in FLT3-ITD-positive AML with respect to allogeneic transplantation.

    Richard F Schlenk;Sabine Kayser;Lars Bullinger;Guido Kobbe

  • Suppression of antitumor T cell immunity by the oncometabolite ( R )-2-hydroxyglutarate

    Lukas Bunse;Stefan Pusch;Theresa Bunse;Felix Sahm

  • A genomewide screen for autism: strong evidence for linkage to chromosomes 2q, 7q and 16p

    Le, Couteur, A;TP Kelly;T Berney;HR McConachie

  • Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers

    Yvette Schwitalle;Matthias Kloor;Susanne Eiermann;Michael Linnebacher

  • Multivariable regression model building by using fractional polynomials: Description of SAS, STATA and R programs

    W. Sauerbrei;C. Meier-Hirmer;A. Benner;P. Royston

Frequent Co-Authors

Hartmut Döhner
Hartmut Döhner University of Ulm
Anthony D. Ho
Anthony D. Ho University Hospital Heidelberg
Hartmut Goldschmidt
Hartmut Goldschmidt University Hospital Heidelberg
Peter Lichter
Peter Lichter German Cancer Research Center
Richard F. Schlenk
Richard F. Schlenk University Hospital Heidelberg
Anna Jauch
Anna Jauch Heidelberg University
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Konstanze Döhner
Konstanze Döhner University of Ulm
Stephan Stilgenbauer
Stephan Stilgenbauer University of Ulm
Andreas E. Kulozik
Andreas E. Kulozik Heidelberg University

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