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Microbiology

D-Index
43
Citations
5998
World Ranking
5295
National Ranking
2011

Overview

Matteo Porotto is affiliated with Columbia University in the United States and has a significant research portfolio focused on medicine, with particular emphasis on epidemiology, infectious diseases, molecular biology, immunology, and pulmonary and respiratory medicine. Their research encompasses virology and viral diseases, especially SARS-CoV-2 and COVID-19 related studies.

The scientist's work spans several specific topics, including:

  • Virology and Viral Diseases
  • SARS-CoV-2 and COVID-19 Research
  • Respiratory viral infections research
  • COVID-19 Clinical Research Studies
  • Viral Infections and Vectors
  • Influenza Virus Research Studies
  • Viral Infections and Immunology Research

Matteo Porotto has published extensively in venues known for biomedical and clinical research. The most frequent publication outlets include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • mBio
  • Nature Communications
  • EMPIAR dataset
  • Science

The scientist's recent published papers cover various aspects of SARS-CoV-2 infection, immune responses, and viral transmission:

  • "Distinct antibody responses to SARS-CoV-2 in children and adults across the COVID-19 clinical spectrum," 2020, Nature Immunology
  • "In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age," 2020, PLoS Biology
  • "Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets," 2021, Science
  • "Inhibition of Coronavirus Entry In Vitro and Ex Vivo by a Lipid-Conjugated Peptide Derived from the SARS-CoV-2 Spike Glycoprotein HRC Domain," 2020, mBio
  • "Antibody responses to SARS-CoV2 are distinct in children with MIS-C compared to adults with COVID-19," 2020, bioRxiv (Cold Spring Harbor Laboratory)

Frequent collaborators in their research include:

  • Anne Moscona
  • Francesca T. Bovier
  • Alexander L. Greninger
  • Tara C. Marcink
  • Cyrille Mathieu

Best Publications

  • A three-dimensional model of human lung development and disease from pluripotent stem cells

    Ya-Wen Chen;Sarah Xuelian Huang;Ana Luisa Rodrigues Toste de Carvalho;Siu-Hong Ho

  • Distinct antibody responses to SARS-CoV-2 in children and adults across the COVID-19 clinical spectrum.

    Stuart P. Weisberg;Thomas J. Connors;Yun Zhu;Matthew R. Baldwin

  • In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age.

    Nicole A.P. Lieberman;Vikas Peddu;Hong Xie;Lasata Shrestha

  • Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets.

    Rory D. de Vries;Katharina S. Schmitz;Francesca T. Bovier;Francesca T. Bovier;Camilla Predella;Camilla Predella

  • Inhibition of Nipah Virus Infection In Vivo: Targeting an Early Stage of Paramyxovirus Fusion Activation during Viral Entry

    Matteo Porotto;Barry Rockx;Christine C. Yokoyama;Aparna Talekar

  • Authentic Modeling of Human Respiratory Virus Infection in Human Pluripotent Stem Cell-Derived Lung Organoids.

    M. Porotto;M. Ferren;Y.-W. Chen;Y. Siu

  • A Second Receptor Binding Site on Human Parainfluenza Virus Type 3 Hemagglutinin-Neuraminidase Contributes to Activation of the Fusion Mechanism

    Matteo Porotto;Micaela Fornabaio;Glen E. Kellogg;Anne Moscona

  • Triggering of human parainfluenza virus 3 fusion protein (F) by the hemagglutinin-neuraminidase (HN) protein: an HN mutation diminishes the rate of F activation and fusion.

    Matteo Porotto;Matthew Murrell;Olga Greengard;Anne Moscona

  • Viral Entry Inhibitors Targeted to the Membrane Site of Action

    Matteo Porotto;Christine C. Yokoyama;Laura M. Palermo;Bruce Mungall

  • Simulating Henipavirus Multicycle Replication in a Screening Assay Leads to Identification of a Promising Candidate for Therapy

    Matteo Porotto;Gianmarco Orefice;Christine C. Yokoyama;Bruce A. Mungall

  • Molecular Determinants of Antiviral Potency of Paramyxovirus Entry Inhibitors

    M. Porotto;P. Carta;Y. Deng;G. E. Kellogg

  • Influence of the Human Parainfluenza Virus 3 Attachment Protein's Neuraminidase Activity on Its Capacity To Activate the Fusion Protein

    Matteo Porotto;Matthew Murrell;Olga Greengard;Lynne Doctor

  • A Recombinant Sialidase Fusion Protein Effectively Inhibits Human Parainfluenza Viral Infection in Vitro and in Vivo

    Anne Moscona;Matteo Porotto;Samantha Palmer;Caroline Tai

  • Mechanism of Fusion Triggering by Human Parainfluenza Virus Type III COMMUNICATION BETWEEN VIRAL GLYCOPROTEINS DURING ENTRY

    Matteo Porotto;Samantha G. Palmer;Laura M. Palermo;Anne Moscona

  • Human Parainfluenza Virus Infection of the Airway Epithelium: Viral Hemagglutinin-Neuraminidase Regulates Fusion Protein Activation and Modulates Infectivity

    Laura M. Palermo;Matteo Porotto;Christine C. Yokoyama;Samantha G. Palmer

  • Paramyxovirus Receptor-Binding Molecules: Engagement of One Site on the Hemagglutinin-Neuraminidase Protein Modulates Activity at the Second Site

    Matteo Porotto;Micaela Fornabaio;Olga Greengard;Matthew T. Murrell

  • Intermediates in SARS-CoV-2 spike–mediated cell entry

    Unknown

  • The Second Receptor Binding Site of the Globular Head of the Newcastle Disease Virus Hemagglutinin-Neuraminidase Activates the Stalk of Multiple Paramyxovirus Receptor Binding Proteins To Trigger Fusion

    Matteo Porotto;Zuhair Salah;Ilaria DeVito;Aparna Talekar

  • Human parainfluenza virus type 3 HN-receptor interaction: effect of 4-guanidino-Neu5Ac2en on a neuraminidase-deficient variant.

    Matteo Porotto;Olga Greengard;Natalia Poltoratskaia;Maria-Arantxa Horga

  • Inhibition of Hendra Virus Fusion

    M. Porotto;L. Doctor;P. Carta;M. Fornabaio

  • Inhibition of Coronavirus Entry In Vitro and Ex Vivo by a Lipid-Conjugated Peptide Derived from the SARS-CoV-2 Spike Glycoprotein HRC Domain.

    Victor K. Outlaw;Francesca T. Bovier;Francesca T. Bovier;Megan C. Mears;Maria N. Cajimat

  • Intranasal fusion inhibitory lipopeptide prevents direct contact SARS-CoV-2 transmission in ferrets

    Rory D de Vries;Katharina S Schmitz;Francesca T Bovier;Francesca T Bovier;Danny Noack

Frequent Co-Authors

Anne Moscona
Anne Moscona Columbia University
Samuel H. Gellman
Samuel H. Gellman University of Wisconsin–Madison
Alexander L. Greninger
Alexander L. Greninger University of Washington
Rik L. de Swart
Rik L. de Swart Erasmus University Rotterdam
Joshua D. Milner
Joshua D. Milner Columbia University
Donna L. Farber
Donna L. Farber Columbia University
Bart L. Haagmans
Bart L. Haagmans Erasmus University Rotterdam
Emily M. Mace
Emily M. Mace Columbia University

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