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Chemistry

D-Index
50
Citations
7288
World Ranking
14575
National Ranking
3725

Overview

Glen E. Kellogg is affiliated with Virginia Commonwealth University in the United States. Their research primarily falls within Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology, where they have contributed to 40 publications. Additional subfields of study include Computational Theory and Mathematics, Spectroscopy, Materials Chemistry, and Cell Biology.

Their work covers diverse topics, notably Protein Structure and Dynamics, which accounts for nearly half of their research efforts. Other main areas include Computational Drug Discovery Methods, Enzyme Structure and Function, Protein Degradation and Inhibitors, Mitochondrial Function and Pathology, Ubiquitin and Proteasome Pathways, and Molecular Spectroscopy and Chirality.

Glen E. Kellogg has published in a variety of scientific journals, frequently contributing to Frontiers in Molecular Biosciences, with four publications in this venue. Other common publication venues include the Journal of Biological Chemistry, International Journal of Molecular Sciences, bioRxiv (Cold Spring Harbor Laboratory), and Molecular Therapy.

Recent selected papers by Kellogg reflect their interest in molecular and structural biology as well as cancer and protein interaction research:

  • "FOSL1 promotes metastasis of head and neck squamous cell carcinoma through super-enhancer-driven transcription program," 2021, Molecular Therapy
  • "3D interaction homology: The hydrophobic residues alanine, isoleucine, leucine, proline and valine play different structural roles in soluble and membrane proteins," 2023, Frontiers in Molecular Biosciences
  • "Novel eIF4A1 inhibitors with anti-tumor activity in lymphoma," 2022, Molecular Medicine
  • "3D Interaction Homology: Hydropathic Analyses of the 'π-Cation' and 'π-π' Interaction Motifs in Phenylalanine, Tyrosine, and Tryptophan Residues," 2021, Journal of Chemical Information and Modeling
  • "3D interaction homology: Hydropathic interaction environments of serine and cysteine are strikingly different and their roles adapt in membrane proteins," 2021, Current Research in Structural Biology

Frequent co-authors collaborating with Kellogg include Mohammed H. AL Mughram, Noah B. Herrington, Claudio Catalano, Martin K. Safo, and Youzhong Guo. These collaborations likely contribute to multidisciplinary approaches in their research, combining expertise across molecular biology, computational methods, and structural analysis.

Best Publications

  • HINT: A new method of empirical hydrophobic field calculation for CoMFA

    Glen E. Kellogg;Simon F. Semus;Donald J. Abraham

  • Target flexibility: an emerging consideration in drug discovery and design.

    Pietro Cozzini;Glen E. Kellogg;Francesca Spyrakis;Donald J. Abraham

  • Hydrophobicity: is LogPo/w more than the sum of its parts?

    Glen Eugene Kellogg;Donald J. Abraham

  • Allosteric modifiers of hemoglobin. 2. Crystallographically determined binding sites and hydrophobic binding/interaction analysis of novel hemoglobin oxygen effectors.

    Fred C. Wireko;Glen E. Kellogg;Donald J. Abraham

  • Hydrophobicity - Shake Flasks, Protein Folding and Drug Discovery

    Aurijit Sarkar;Glen E. Kellogg

  • Simple, intuitive calculations of free energy of binding for protein-ligand complexes. 1. Models without explicit constrained water.

    Pietro Cozzini;Micaela Fornabaio;Anna Marabotti;Donald J. Abraham

  • Transport and Structural Studies of Sulfonated Styrene-Ethylene Copolymer Membranes

    J. M. Serpico;S. G. Ehrenberg;J. J. Fontanella;X. Jiao

  • The Roles of Water in the Protein Matrix: A Largely Untapped Resource for Drug Discovery

    Francesca Spyrakis;Mostafa H. Ahmed;Alexander S. Bayden;Pietro Cozzini

  • Simple, intuitive calculations of free energy of binding for protein-ligand complexes. 3. The free energy contribution of structural water molecules in HIV-1 protease complexes

    Micaela Fornabaio;Francesca Spyrakis;Andrea Mozzarelli;Pietro Cozzini

  • E-state fields: Applications to 3D QSAR

    Glen Eugene Kellogg;Lemont B. Kier;Patrick Gaillard;Lowell H. Hall

  • Free energy of ligand binding to protein: evaluation of the contribution of water molecules by computational methods.

    Pietro Cozzini;Micaela Fornabaio;Anna Marabotti;Donald J. Abraham

  • A Second Receptor Binding Site on Human Parainfluenza Virus Type 3 Hemagglutinin-Neuraminidase Contributes to Activation of the Fusion Mechanism

    Matteo Porotto;Micaela Fornabaio;Glen E. Kellogg;Anne Moscona

  • Differences in hydropathic properties of ligand binding at four independent sites in wheat germ agglutinin-oligosaccharide crystal complexes

    Christine Schubert Wright;Glen E. Kellogg

  • 3,5-Disubstituted-thiazolidine-2,4-dione analogs as anticancer agents: design, synthesis and biological characterization.

    Kai Liu;Wei Rao;Hardik Parikh;Qianbin Li

  • Tyrosine nitration of IκBα : A novel mechanism for NF-κB activation

    Vasily A. Yakovlev;Igor J. Barani;Christopher S. Rabender;Stephen Matthew Black

  • Simple, intuitive calculations of free energy of binding for protein-ligand complexes. 2. Computational titration and pH effects in molecular models of neuraminidase-inhibitor complexes.

    Micaela Fornabaio;Pietro Cozzini;Andrea Mozzarelli;Donald J. Abraham

  • 1,2-Dithiole-3-ones as potent inhibitors of the bacterial 3-ketoacyl acyl carrier protein synthase III (FabH)

    Xin He;Anne McElwee Reeve;Umesh R. Desai;Glen E. Kellogg

  • Robust Classification of “Relevant” Water Molecules in Putative Protein Binding Sites

    Alessio Amadasi;J. Andrew Surface;Francesca Spyrakis;Pietro Cozzini

  • Biological Characterization of 3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione (K145) as a Selective Sphingosine Kinase-2 Inhibitor and Anticancer Agent

    Kai Liu;Tai L. Guo;Nitai C. Hait;Jeremy Allegood

  • Autophagic cell death, polyploidy and senescence induced in breast tumor cells by the substituted pyrrole JG-03-14, a novel microtubule poison.

    Christopher R. Arthur;John T. Gupton;Glen E. Kellogg;W. Andrew Yeudall

  • Mapping the energetics of water-protein and water-ligand interactions with the "natural" HINT forcefield: predictive tools for characterizing the roles of water in biomolecules.

    Alessio Amadasi;Francesca Spyrakis;Pietro Cozzini;Donald J. Abraham

Frequent Co-Authors

Andrea Mozzarelli
Andrea Mozzarelli University of Parma
Dennis L. Lichtenberger
Dennis L. Lichtenberger University of Arizona
Anne Moscona
Anne Moscona Columbia University
Tobin J. Marks
Tobin J. Marks Northwestern University
Paul F. Cook
Paul F. Cook University of Oklahoma
Carl R. Kannewurf
Carl R. Kannewurf Northwestern University
Kristoffer Valerie
Kristoffer Valerie Virginia Commonwealth University
Steven Grant
Steven Grant Virginia Commonwealth University
Gabriele Cruciani
Gabriele Cruciani University of Perugia
David A. Gewirtz
David A. Gewirtz Virginia Commonwealth University

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