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Andrea Mozzarelli

Andrea Mozzarelli

D-Index & Metrics

Chemistry

D-Index
55
Citations
10074
World Ranking
12209
National Ranking
399

Overview

Andrea Mozzarelli is affiliated with the University of Parma in Italy and has contributed extensively to fields related to Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their research spans multiple subfields including Molecular Biology, Biochemistry, Cell Biology, Biotechnology, and Physiology.

The main topics of Andrea Mozzarelli's work encompass:

  • Amino Acid Enzymes and Metabolism
  • Hemoglobin structure and function
  • Biochemical and Molecular Research
  • Cancer Research and Treatments
  • Epigenetics and DNA Methylation
  • Heme Oxygenase-1 and Carbon Monoxide
  • Enzyme Structure and Function

Andrea Mozzarelli has published in several scientific journals, with frequent publications in:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Current Medicinal Chemistry
  • FEBS Journal
  • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  • Frontiers in Molecular Biosciences

Recent papers authored or coauthored by Mozzarelli include:

  • "From hemoglobin allostery to hemoglobin-based oxygen carriers," 2021, Molecular Aspects of Medicine
  • "Enzyme Replacement Therapy for Genetic Disorders Associated with Enzyme Deficiency," 2021, Current Medicinal Chemistry
  • "Investigational Studies on a Hit Compound Cyclopropane-Carboxylic Acid Derivative Targeting O-Acetylserine Sulfhydrylase as a Colistin Adjuvant," 2021, ACS Infectious Diseases
  • "Inhibition of Nonessential Bacterial Targets: Discovery of a Novel Serine O-Acetyltransferase Inhibitor," 2020, ACS Medicinal Chemistry Letters
  • "Engineering hemoglobin to enable homogenous PEGylation without modifying protein functionality," 2020, Biomaterials Science

Frequent coauthors collaborating with Andrea Mozzarelli include:

  • Stefano Bettati
  • Serena Faggiano
  • Stefano Bruno
  • Barbara Campanini
  • Luca Ronda

Best Publications

  • Is cooperative oxygen binding by hemoglobin really understood

    William A. Eaton;Eric R. Henry;James Hofrichter;Andrea Mozzarelli

  • Delay time of hemoglobin S polymerization prevents most cells from sickling in vivo

    Andrea Mozzarelli;James Hofrichter;William A. Eaton

  • Pyridoxal 5-Phosphate Enzymes as Targets for Therapeutic Agents

    Alessio Amadasi;Mariarita Bertoldi;Roberto Contestabile;Stefano Bettati

  • Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.

    Andrea Mattevi;Marco W. Fraaije;Andrea Mozzarelli;Luca Olivi

  • Structures of gamma-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin.

    Paola Storici;Daniela De Biase;Francesco Bossa;Stefano Bruno

  • "Muscle to meat" molecular events and technological transformations: The proteomics insight ☆

    Gianluca Paredi;Samanta Raboni;Emøke Bendixen;André M. de Almeida

  • Simple, intuitive calculations of free energy of binding for protein-ligand complexes. 1. Models without explicit constrained water.

    Pietro Cozzini;Micaela Fornabaio;Anna Marabotti;Donald J. Abraham

  • The Roles of Water in the Protein Matrix: A Largely Untapped Resource for Drug Discovery

    Francesca Spyrakis;Mostafa H. Ahmed;Alexander S. Bayden;Pietro Cozzini

  • Oxygen binding by single crystals of hemoglobin.

    Claudio Rivetti;Andrea Mozzarelli;Gian Luigi Rossi;Eric R. Henry

  • T State Hemoglobin Binds Oxygen Noncooperatively with Allosteric Effects of Protons, Inositol Hexaphosphate, and Chloride

    Stefano Bettati;Andrea Mozzarelli

  • Drug Discovery Targeting Amino Acid Racemases

    Paola Conti;Lucia Tamborini;Andrea Pinto;Arnaud Blondel

  • PROTEIN FUNCTION IN THE CRYSTAL

    Andrea Mozzarelli;Gian Luigi Rossi

  • Simple, intuitive calculations of free energy of binding for protein-ligand complexes. 3. The free energy contribution of structural water molecules in HIV-1 protease complexes

    Micaela Fornabaio;Francesca Spyrakis;Andrea Mozzarelli;Pietro Cozzini

  • Crystals of haemoglobin with the T quaternary structure bind oxygen noncooperatively with no Bohr effect.

    Andrea Mozzarelli;Claudio Rivetti;Gian Luigi Rossi;Eric R. Henry

  • New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels

    Cristiano Viappiani;Stefano Bettati;Stefano Bruno;Luca Ronda

  • Free energy of ligand binding to protein: evaluation of the contribution of water molecules by computational methods.

    Pietro Cozzini;Micaela Fornabaio;Anna Marabotti;Donald J. Abraham

  • Evolution of allosteric models for hemoglobin

    William A. Eaton;Eric R. Henry;James Hofrichter;Stefano Bettati

  • High and low oxygen affinity conformations of T state hemoglobin

    Stefano Bruno;Maria Bonaccio;Stefano Bettati;Claudio Rivetti

  • Identification of Xenoestrogens in Food Additives by an Integrated in Silico and in Vitro Approach

    Alessio Amadasi;Andrea Mozzarelli;Clara Meda;Adriana Maggi

  • Simple, intuitive calculations of free energy of binding for protein-ligand complexes. 2. Computational titration and pH effects in molecular models of neuraminidase-inhibitor complexes.

    Micaela Fornabaio;Pietro Cozzini;Andrea Mozzarelli;Donald J. Abraham

Frequent Co-Authors

Glen E. Kellogg
Glen E. Kellogg Virginia Commonwealth University
Paul F. Cook
Paul F. Cook University of Oklahoma
Martino Bolognesi
Martino Bolognesi University of Milan
Chris E. Cooper
Chris E. Cooper University of Essex
Robert S. Phillips
Robert S. Phillips University of Georgia
Sylvia Dewilde
Sylvia Dewilde University of Antwerp
Simone Ottonello
Simone Ottonello University of Parma
Leif Bülow
Leif Bülow Lund University
Luc Moens
Luc Moens University of Antwerp
Loredano Pollegioni
Loredano Pollegioni University of Insubria

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