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Chemistry

D-Index
53
Citations
9031
World Ranking
13178
National Ranking
3467

Overview

Robert S. Phillips is affiliated with the University of Georgia in the United States. Their research spans multiple fields, including Biochemistry, Genetics and Molecular Biology, as well as Materials Science. The work is distributed across several subfields such as Molecular Biology, Biochemistry, Materials Chemistry, Biological Psychiatry, and Organic Chemistry.

The scientist's main topics of study elaborate on enzyme-related biochemical processes and include:

  • Enzyme Structure and Function
  • Amino Acid Enzymes and Metabolism
  • Tryptophan and brain disorders
  • Biochemical Acid Research Studies
  • Biochemical and Molecular Research
  • Polyamine Metabolism and Applications
  • Enzyme Catalysis and Immobilization

Phillips has contributed publications to several frequent venues, reflecting a focus on biochemical and catalytic studies. These venues include:

  • Archives of Biochemistry and Biophysics
  • ChemBioChem
  • FEBS Journal
  • Biochemistry
  • ACS Catalysis

Recent papers authored or co-authored by Phillips highlight various biochemical and enzymatic investigations. Notable recent works are:

  • The Kynurenine Pathway and Kynurenine 3-Monooxygenase Inhibitors, 2022, Molecules
  • New cases that expand the genotypic and phenotypic spectrum of Congenital NAD Deficiency Disorder, 2021, Human Mutation
  • Oxygen reactivity with pyridoxal 5'-phosphate enzymes: biochemical implications and functional relevance, 2020, Amino Acids
  • Secondary Alcohol Dehydrogenases from Thermoanaerobacter pseudoethanolicus and Thermoanaerobacter brockii as Robust Catalysts, 2021, ChemBioChem
  • The crystal structure of the S154Y mutant carbonyl reductase from Leifsonia xyli explains enhanced activity for 3,5-bis(trifluoromethyl)acetophenone reduction, 2022, Archives of Biochemistry and Biophysics

Phillips collaborates frequently with other researchers, with several co-authors contributing multiple works together. Frequent co-authors include:

  • Victoria N. Drago
  • Andrey Kovalevsky
  • Giovanni Bisello
  • Mariarita Bertoldi
  • Matthew P. Blakeley

Best Publications

  • Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4.

    Madhukumar Venkatesh;Subhajit Mukherjee;Hongwei Wang;Hao Li

  • Indole can act as an extracellular signal to regulate biofilm formation of Escherichia coli and other indole-producing bacteria.

    P Di Martino;R Fursy;L Bret;B Sundararaju

  • Temperature modulation of the stereochemistry of enzymatic catalysis: Prospects for exploitation

    Robert S. Phillips

  • Three-dimensional structure of tyrosine phenol-lyase.

    A.A Antson;T.V Demidkina;P Gollnick;Z Dauter

  • Recent advances in alcohol dehydrogenase-catalyzed asymmetric production of hydrophobic alcohols

    Musa M. Musa;Robert S. Phillips

  • The entropic force generated by intrinsically disordered segments tunes protein function

    Keul Nd;Oruganty K;Schaper Bergman Et;Beattie Nr

  • A redox-active FKBP-type immunophilin functions in accumulation of the photosystem II supercomplex in Arabidopsis thaliana

    Amparo Lima;Santiago Lima;Joshua H. Wong;Robert S. Phillips

  • Asymmetric Reduction and Oxidation of Aromatic Ketones and Alcohols Using W110A Secondary Alcohol Dehydrogenase from Thermoanaerobacter ethanolicus

    Musa M Musa;Karla I Ziegelmann-Fjeld;Claire Vieille;J Gregory Zeikus

  • Temperature effects on stereochemistry of enzymatic reactions

    Robert S. Phillips

  • Controlling Substrate Specificity and Stereospecificity of Alcohol Dehydrogenases

    Christopher M. Nealon;Musa M. Musa;Jay M. Patel;Robert S. Phillips

  • Interactions of tryptophan synthase, tryptophanase, and pyridoxal phosphate with oxindolyl-L-alanine and 2,3-dihydro-L-tryptophan: support for an indolenine intermediate in tryptophan metabolism.

    Robert S. Phillips;Edith Wilson Miles;Louis A. Cohen

  • Kinetics and mechanism of superoxide reduction by two-iron superoxide reductase from Desulfovibrio vulgaris.

    Joseph P. Emerson;Eric D. Coulter;Diane E. Cabelli;Robert S. Phillips

  • Temperature-dependent enantiospecificity of secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus

    Van T. Pham;Robert S. Phillips;Lars G. Ljungdahl

  • Effects of substrate structure and temperature on the stereospecificity of secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus

    Van T. Pham;Robert S. Phillips

  • Chemistry and diversity of pyridoxal-5'-phosphate dependent enzymes.

    Robert S. Phillips

  • Xerogel-Encapsulated W110A Secondary Alcohol Dehydrogenase from Thermoanaerobacter ethanolicus Performs Asymmetric Reduction of Hydrophobic Ketones in Organic Solvents**

    Musa M. Musa;Karla I. Ziegelmann-Fjeld;Claire Vieille;J. Gregory Zeikus

  • S-aryl-L-cysteine S,S-dioxides : design, synthesis, and evaluation of a new class of inhibitors of kynureninase

    Rajesh K. Dua;Ethan W. Taylor;Robert S. Phillips

  • Mutation of Cysteine-295 to Alanine in Secondary Alcohol Dehydrogenase from Thermoanaerobacter ethanolicus Affects the Enantioselectivity and Substrate Specificity of Ketone Reductions

    Christian Heiss;Maris Laivenieks;J.Gregory Zeikus;Robert S Phillips

  • Proteolytic modification of the amino-terminal and carboxyl-terminal regions of rat hepatic phenylalanine hydroxylase.

    Masayoshi Iwaki;Robert S. Phillips;Seymour Kaufman

  • A Single Point Mutation Reverses the Enantiopreference of Thermoanaerobacter ethanolicus Secondary Alcohol Dehydrogenase

    Musa M. Musa;Nathan Lott;Maris Laivenieks;Leandra Watanabe

  • Synthetic applications of tryptophan synthase

    Unknown

Frequent Co-Authors

Edith Wilson Miles
Edith Wilson Miles National Institutes of Health
Casimir C. Akoh
Casimir C. Akoh University of Georgia
Donald M. Kurtz
Donald M. Kurtz The University of Texas at San Antonio
Kenneth L. Kirk
Kenneth L. Kirk National Institutes of Health
Seymour Kaufman
Seymour Kaufman National Institutes of Health
I. Jonathan Amster
I. Jonathan Amster University of Georgia
Peter McPhie
Peter McPhie National Institutes of Health
Andrea Mozzarelli
Andrea Mozzarelli University of Parma
Karl-Erik Eriksson
Karl-Erik Eriksson University of Georgia
Sally L. Dunwoodie
Sally L. Dunwoodie Victor Chang Cardiac Research Institute

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