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Chemistry

D-Index
57
Citations
12295
World Ranking
11032
National Ranking
1778

Overview

Jian-He Xu is affiliated with East China University of Science and Technology in China. Their research primarily focuses on fields within Biochemistry, Genetics and Molecular Biology, with a total of 155 publications recorded in this domain.

The scientist's work encompasses several specialized subfields, including Molecular Biology, Biomedical Engineering, Organic Chemistry, Pharmacology, and Biochemistry. These subfields reflect a diverse range of interdisciplinary approaches within the biological and chemical sciences.

The main topics addressed in Jian-He Xu's research include:

  • Enzyme Catalysis and Immobilization
  • Microbial Metabolic Engineering and Bioproduction
  • Biochemical and Molecular Research
  • Catalysis for Biomass Conversion
  • Chemical Synthesis and Analysis
  • Plant Biochemistry and Biosynthesis
  • Asymmetric Hydrogenation and Catalysis

Jian-He Xu has contributed to multiple publications in scientific journals, including the following papers with year and venue:

  • Discovery of an Imine Reductase for Reductive Amination of Carbonyl Compounds with Sterically Challenging Amines, 2023, Journal of the American Chemical Society
  • Development of an engineered thermostable amine dehydrogenase for the synthesis of structurally diverse chiral amines, 2020, Catalysis Science & Technology
  • Enzymatic Preparation of the Chiral (S)-Sulfoxide Drug Esomeprazole at Pilot-Scale Levels, 2020, Organic Process Research & Development
  • Catalytic conversion of corncob to furfuryl alcohol in tandem reaction with tin-loaded sulfonated zeolite and NADPH-dependent reductase biocatalyst, 2020, Bioresource Technology
  • Enhanced Thermostability of Candida Ketoreductase by Computation-Based Cross-Regional Combinatorial Mutagenesis, 2023, ACS Catalysis

The frequent publication venues for Jian-He Xu include:

  • ACS Catalysis
  • ACS Sustainable Chemistry & Engineering
  • Journal of Agricultural and Food Chemistry
  • Molecular Catalysis
  • Bioresources and Bioprocessing

Collaborations have been an important aspect of Jian-He Xu's scientific activities. Frequent coauthors associated with Xu's work are:

  • Hui-Lei Yu
  • Qi Chen
  • Gao-Wei Zheng
  • Jiang Pan
  • Yu-Cong Zheng

Best Publications

  • Biocatalysis in development of green pharmaceutical processes

    Junhua Tao;Jian-He Xu

  • Biocatalytic ketone reduction: a green and efficient access to enantiopure alcohols.

    Yan Ni;Jian-He Xu

  • Cloning and characterization of a panel of constitutive promoters for applications in pathway engineering in Saccharomyces cerevisiae

    Jie Sun;Zengyi Shao;Hua Zhao;Nikhil Nair

  • New opportunities for biocatalysis: driving the synthesis of chiral chemicals.

    Gao-Wei Zheng;Jian-He Xu

  • Immobilization of Serratia marcescens lipase onto amino-functionalized magnetic nanoparticles for repeated use in enzymatic synthesis of Diltiazem intermediate

    Bin Hu;Jiang Pan;Hui-Lei Yu;Jian-Wen Liu

  • Highly efficient synthesis of chiral alcohols with a novel NADH-dependent reductase from Streptomyces coelicolor.

    Li-Juan Wang;Chun-Xiu Li;Yan Ni;Jie Zhang

  • Asymmetric Amination of Secondary Alcohols by using a Redox-Neutral Two-Enzyme Cascade

    Fei‐Fei Chen;You‐Yan Liu;You‐Yan Liu;Gao‐Wei Zheng;Jian‐He Xu

  • Reshaping the Active Pocket of Amine Dehydrogenases for Asymmetric Synthesis of Bulky Aliphatic Amines

    Fei-Fei Chen;Gao-Wei Zheng;Lei Liu;Hao Li

  • Biochemical properties and potential applications of an organic solvent-tolerant lipase isolated from Serratia marcescens ECU1010

    Li-Li Zhao;Jian-He Xu;Jian Zhao;Jiang Pan

  • Reshaping an Enzyme Binding Pocket for Enhanced and Inverted Stereoselectivity: Use of Smallest Amino Acid Alphabets in Directed Evolution

    Zhoutong Sun;Zhoutong Sun;Richard Lonsdale;Richard Lonsdale;Xu-Dong Kong;Jian-He Xu

  • Catalytic Promiscuity of Ancestral Esterases and Hydroxynitrile Lyases.

    Titu Devamani;Alissa M. Rauwerdink;Mark Lunzer;Bryan J. Jones

  • Identification, purification and characterization of β-glucosidase from apple seed as a novel catalyst for synthesis of O-glucosides

    Hui-Lei Yu;Jian-He Xu;Wen-Ya Lu;Guo-Qiang Lin

  • Enhancing effect of Tween-80 on lipase performance in enantioselective hydrolysis of ketoprofen ester

    Unknown

  • Asymmetric reduction of ketones by employing Rhodotorula sp. AS2.2241 and synthesis of the β-blocker (R)-nifenalol

    Wei Yang;Jian-He Xu;Yan Xie;Yi Xu

  • Newly Identified Thermostable Esterase from Sulfobacillus acidophilus: Properties and Performance in Phthalate Ester Degradation

    Xiao-Yan Zhang;Xiang Fan;Yong-Jun Qiu;Cheng-Yuan Li

  • Cloud point of nonionic surfactant Triton X-45 in aqueous solution.

    Zhilong Wang;Jian-He Xu;Wenzhi Zhang;Wenzhi Zhang;Baohua Zhuang

  • Bioproduction of glycolic acid from glycolonitrile with a new bacterial isolate of Alcaligenes sp. ECU0401.

    Yu-Cai He;Jian-He Xu;Jin-Huan Su;Li Zhou

  • Direct Conversion of Xylan to Ethanol by Recombinant Saccharomyces cerevisiae Strains Displaying an Engineered Minihemicellulosome

    Jie Sun;Jie Sun;Fei Wen;Tong Si;Jian He Xu

  • Access to Optically Active Aryl Halohydrins Using a Substrate-Tolerant Carbonyl Reductase Discovered from Kluyveromyces thermotolerans

    Guo-Chao Xu;Hui-Lei Yu;Xiao-Yan Zhang;Jian-He Xu

  • Two-step enzymatic synthesis of ursodeoxycholic acid with a new 7β-hydroxysteroid dehydrogenase from Ruminococcus torques

    Ming-Min Zheng;Ru-Feng Wang;Chun-Xiu Li;Jian-He Xu

  • Optimization of Serratia marcescens lipase production for enantioselective hydrolysis of 3-phenylglycidic acid ester.

    Li Gao;Jian-He Xu;Xin-Jun Li;Zuo-Zhen Liu

  • Bio-resolution of a chiral epoxide using whole cells of Bacillus megaterium ECU1001 in a biphasic system

    Peng-Fei Gong;Jian-He Xu

Frequent Co-Authors

Manfred T. Reetz
Manfred T. Reetz Max Planck Society
Antony M. Dean
Antony M. Dean University of Minnesota
Isabel W. C. E. Arends
Isabel W. C. E. Arends Utrecht University
Sunghoon Park
Sunghoon Park Ulsan National Institute of Science and Technology
Frank Hollmann
Frank Hollmann Delft University of Technology
Yun Tang
Yun Tang East China University of Science and Technology
Sheng Yang
Sheng Yang Chinese Academy of Sciences
Jian-Jiang Zhong
Jian-Jiang Zhong Shanghai Jiao Tong University
Huimin Zhao
Huimin Zhao University of Illinois at Urbana-Champaign
Li-Min Zhu
Li-Min Zhu Donghua University

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