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Chemistry

D-Index
92
Citations
28575
World Ranking
1900
National Ranking
105

Research.com Recognitions

  • 2020 - Fellow of the Royal Society, United Kingdom

Overview

Nicholas J. Turner is affiliated with the University of Manchester in the United Kingdom. Their research activity spans fields primarily related to Biochemistry, Genetics and Molecular Biology, and Chemistry. Within these broader areas, their work frequently intersects with subfields including Molecular Biology, Organic Chemistry, Biomedical Engineering, Inorganic Chemistry, and Pharmacology.

The scientist's research topics reflect a concentration on enzyme catalysis and related chemical processes. The main topics of their work include:

  • Enzyme Catalysis and Immobilization
  • Asymmetric Hydrogenation and Catalysis
  • Chemical Synthesis and Analysis
  • Microbial Metabolic Engineering and Bioproduction
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Microbial Natural Products and Biosynthesis
  • Click Chemistry and Applications

Turner has published multiple recent papers in high-impact scientific venues, illustrating the scope and focus of their work. Selected recent publications are:

  • "Biocatalysis," published in 2021 in Nature Reviews Methods Primers
  • "RetroBioCat as a computer-aided synthesis planning tool for biocatalytic reactions and cascades," published in 2021 in Nature Catalysis
  • "Screening and characterization of a diverse panel of metagenomic imine reductases for biocatalytic reductive amination," published in 2020 in Nature Chemistry
  • "Enzymatic Late-Stage Modifications: Better Late Than Never," published in 2021 in Angewandte Chemie International Edition
  • "Multifunctional biocatalyst for conjugate reduction and reductive amination," published in 2022 in Nature

Their work has appeared frequently in several publication venues. The most common include:

  • Angewandte Chemie International Edition
  • Angewandte Chemie
  • ACS Catalysis
  • Journal of the American Chemical Society
  • JACS Au

In addition to journal articles, Turner has contributed to academic books published by notable academic presses such as Springer International Publishing and WORLD SCIENTIFIC (EUROPE) eBooks. These include the titles:

  • "Frustrated Lewis Pairs" (2020)
  • "Modern Developments in Catalysis" (2021)

Collaboration is an important aspect of Turner's research, with frequent co-authors including:

  • Sabine L. Flitsch
  • James R. Marshall
  • Rachel S. Heath
  • Sebastian C. Cosgrove
  • Christian Schnepel

Turner has been recognized with awards such as being named a Fellow of the Royal Society, United Kingdom, in 2020.

Best Publications

  • Directed evolution drives the next generation of biocatalysts

    Nicholas J Turner

  • Biocatalytic Approaches to the Synthesis of Enantiomerically Pure Chiral Amines

    Diego Ghislieri;Nicholas J. Turner

  • Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades.

    Francesco G. Mutti;Tanja Knaus;Nigel S. Scrutton;Michael Breuer

  • Extending the application of biocatalysis to meet the challenges of drug development

    Paul N. Devine;Roger M. Howard;Rajesh Kumar;Matthew P. Thompson

  • Constructing Biocatalytic Cascades: In Vitro and in Vivo Approaches to de Novo Multi-Enzyme Pathways

    Lorna J. Hepworth;Nicholas J. Turner;Sabine L. Flitsch

  • Carboxylic acid reductase is a versatile enzyme for the conversion of fatty acids into fuels and chemical commodities

    M. Kalim Akhtar;M. Kalim Akhtar;Nicholas J. Turner;Patrik R. Jones

  • Discovery, Engineering, and Synthetic Application of Transaminase Biocatalysts

    Iustina Slabu;James Louis Galman;Richard C Lloyd;Nicholas J Turner

  • Engineering an enantioselective amine oxidase for the synthesis of pharmaceutical building blocks and alkaloid natural products.

    Diego Ghislieri;Anthony P. Green;Marta Pontini;Simon C. Willies

  • A reductive aminase from Aspergillus oryzae

    Godwin Aleku;Henry Wing-Hong Man;Juan Mangas-Sanchez

  • Synthetic cascades are enabled by combining biocatalysts with artificial metalloenzymes

    V. Köhler;Y. M. Wilson;M. Dürrenberger;D. Ghislieri

  • Enantioselective Chemo- and Biocatalysis: Partners in Retrosynthesis.

    Moritz Hönig;Philipp Sondermann;Nicholas J. Turner;Erick M. Carreira

  • Cytochromes P450 as useful biocatalysts: addressing the limitations

    Elaine O'Reilly;Valentin Köhler;Sabine L. Flitsch;Nicholas J. Turner

  • Deracemization of α-Methylbenzylamine Using an Enzyme Obtained by In Vitro Evolution

    Marina Alexeeva;Alexis Enright;Michael J. Dawson;Mahmoud Mahmoudian

  • Enantioselective Oxidation of C–O and C–N Bonds Using Oxidases

    Nicholas J. Turner

  • Imine reductases (IREDs)

    Juan Mangas-Sanchez;Sarah L Montgomery;Godwin A Aleku

  • Directed evolution of enzymes for applied biocatalysis

    Nicholas J Turner

  • Biocatalysis Using Immobilized Enzymes in Continuous Flow for the Synthesis of Fine Chemicals

    Matthew Thompson;Itziar Penafiel;Sebastian Cronin Cosgrove;Nicholas J Turner

  • Enzyme catalysed deracemisation and dynamic kinetic resolution reactions.

    Nicholas J Turner

  • An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals

    Pablo Carbonell;Adrian J. Jervis;Christopher J. Robinson;Cunyu Yan

  • A chemo-enzymatic route to enantiomerically pure cyclic tertiary amines.

    Colin J Dunsmore;Reuben Carr;Toni Fleming;Nicholas J Turner

  • Directed Evolution of an Amine Oxidase Possessing both Broad Substrate Specificity and High Enantioselectivity

    Reuben Carr;Marina Alexeeva;Alexis Enright;Tom S. C. Eve

  • Biocatalytic retrosynthesis.

    Unknown

Frequent Co-Authors

Sabine L. Flitsch
Sabine L. Flitsch University of Manchester
Gideon Grogan
Gideon Grogan University of York
Jack E. Baldwin
Jack E. Baldwin University of Oxford
Romano V. A. Orru
Romano V. A. Orru Maastricht University
Eelco Ruijter
Eelco Ruijter Vrije Universiteit Amsterdam
Nigel S. Scrutton
Nigel S. Scrutton University of Manchester
Robert M. Adlington
Robert M. Adlington University of Oxford
Perdita E. Barran
Perdita E. Barran University of Manchester
Malcolm D. Walkinshaw
Malcolm D. Walkinshaw University of Edinburgh
Jean-Loup Faulon
Jean-Loup Faulon University of Paris-Saclay

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