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Engineering and Technology

D-Index
48
Citations
7590
World Ranking
4652
National Ranking
89

Overview

Jean-Loup Faulon is affiliated with the University of Paris-Saclay in France. Their research primarily focuses on biochemistry, genetics, and molecular biology, with extensive work in molecular biology as a subfield. Their studies also span genetics, artificial intelligence, biophysics, and radiology, nuclear medicine, and imaging.

Their scientific inquiry covers a wide range of topics including microbial metabolic engineering and bioproduction, gene regulatory network analysis, RNA and protein synthesis mechanisms, CRISPR and genetic engineering, viral infectious diseases and gene expression in insects, protein structure and dynamics, and bacterial genetics and biotechnology.

Selected recent publications by Jean-Loup Faulon illustrate interdisciplinary approaches combining experimental biology with computational techniques. These papers include:

  • "Large scale active-learning-guided exploration for in vitro protein production optimization" (2020) published in Nature Communications
  • "A versatile active learning workflow for optimization of genetic and metabolic networks" (2022) published in Nature Communications
  • "Engineering Escherichia coli towards de novo production of gatekeeper (2S)-flavanones: naringenin, pinocembrin, eriodictyol and homoeriodictyol" (2020) published in Synthetic Biology
  • "A neural-mechanistic hybrid approach improving the predictive power of genome-scale metabolic models" (2023) published in Nature Communications
  • "Differentially Optimized Cell-Free Buffer Enables Robust Expression from Unprotected Linear DNA in Exonuclease-Deficient Extracts" (2022) published in ACS Synthetic Biology

Jean-Loup Faulon frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Zenodo (CERN European Organization for Nuclear Research), Nature Communications, ACS Synthetic Biology, and Biotechnology Advances. Their publishing record indicates sustained contributions across these platforms, reflecting engagement with both preprint and peer-reviewed scientific communication.

Collaborations form a significant part of their research activities. Key coauthors include Thomas Duigou, Pablo Carbonell, Manish Kushwaha, Melchior Du, and Paul Soudier, with multiple joint publications demonstrating ongoing scientific partnerships.

Best Publications

  • Predicting protein--protein interactions using signature products

    Shawn Martin;Diana Roe;Jean-Loup Faulon

  • The signature molecular descriptor. 1. Using extended valence sequences in QSAR and QSPR studies.

    Jean-Loup Faulon;Donald P Visco;Ramdas S Pophale

  • An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals

    Pablo Carbonell;Adrian J. Jervis;Christopher J. Robinson;Cunyu Yan

  • RetroPath2.0: A retrosynthesis workflow for metabolic engineers.

    Baudoin Delépine;Thomas Duigou;Pablo Carbonell;Jean-Loup Faulon

  • Boolean dynamics of genetic regulatory networks inferred from microarray time series data

    Shawn Martin;Zhaoduo Zhang;Anthony Martino;Jean-Loup Faulon

  • Genome scale enzyme–metabolite and drug–target interaction predictions using the signature molecular descriptor

    Jean-Loup Faulon;Milind Misra;Shawn Martin;Ken Sale

  • The Signature Molecular Descriptor. 2. Enumerating Molecules from Their Extended Valence Sequences

    Jean-Loup Faulon;Carla J Churchwell;Donald P Visco

  • Systems chemical biology.

    Tudor I. Oprea;Alexander Tropsha;Jean Loup Faulon;Mark D. Rintoul

  • 3-D Structural Modeling of Humic Acids through Experimental Characterization, Computer Assisted Structure Elucidation and Atomistic Simulations. 1. Chelsea Soil Humic Acid

    Mamadou S. Diallo;Andre Simpson;Paul L. Gassman;Jean Loup Faulon

  • Plug-and-play metabolic transducers expand the chemical detection space of cell-free biosensors

    Peter L. Voyvodic;Amir Pandi;Mathilde Koch;Ismael Conejero;Ismael Conejero

  • The signature molecular descriptor: 3. Inverse-quantitative structure–activity relationship of ICAM-1 inhibitory peptides

    Carla J Churchwell;Mark D Rintoul;Shawn Martin;Donald P Visco

  • A retrosynthetic biology approach to metabolic pathway design for therapeutic production

    Pablo Carbonell;Anne-Gaëlle G Planson;Davide Fichera;Jean-Loup L Faulon

  • Microbial Genes for a Circular and Sustainable Bio-PET Economy

    Manuel Salvador;Umar Abdulmutalib;Jaime Gonzalez;Juhyun Kim

  • Reinforcement Learning for Bioretrosynthesis

    Mathilde Koch;Thomas Duigou;Jean-Loup Faulon

  • A structural model for lignin-derived vitrinite from high-volatile bituminous coal (coalified wood)

    Patrick G. Hatcher;Jean Loup Faulon;Kurt A. Wenzel;George D. Cody

  • Developing a methodology for an inverse quantitative structure-activity relationship using the signature molecular descriptor.

    Donald P. Visco;Ramdas S. Pophale;Mark D. Rintoul;Jean-Loup Faulon

  • Large scale active-learning-guided exploration for in vitro protein production optimization.

    Olivier Borkowski;Mathilde Koch;Agnès Zettor;Amir Pandi

  • XTMS: pathway design in an eXTended metabolic space

    Pablo Carbonell;Pierre Parutto;Joan Herisson;Shashi Bhushan Pandit

  • RetroRules: a database of reaction rules for engineering biology.

    Thomas Duigou;Melchior du Lac;Pablo Carbonell;Jean-Loup Faulon;Jean-Loup Faulon

  • The signature molecular descriptor. 4. Canonizing molecules using extended valence sequences.

    Jean-Loup Faulon;Michael J Collins;Robert D Carr

  • Preliminary Results on Molecular Modeling of Asphaltenes Using Structure Elucidation Programs in Conjunction with Molecular Simulation Programs

    I. Kowalewski;M. Vandenbroucke;A. Y. Huc;M. J. Taylor

  • Isomorphism, Automorphism Partitioning, and Canonical Labeling Can Be Solved in Polynomial-Time for Molecular Graphs

    Jean-Loup Faulon

  • Handbook of Chemoinformatics Algorithms

    Jean-Loup Faulon;Andreas Bender

  • Stochastic Generator of Chemical Structure. 1. Application to the Structure Elucidation of Large Molecules

    Jean-Loup Faulon

Frequent Co-Authors

Neil Swainston
Neil Swainston Epoch BioDesign
Nigel S. Scrutton
Nigel S. Scrutton University of Manchester
Rainer Breitling
Rainer Breitling University of Manchester
Douglas B. Kell
Douglas B. Kell University of Liverpool
Patrick G. Hatcher
Patrick G. Hatcher Old Dominion University
Eriko Takano
Eriko Takano University of Manchester
Nicholas J. Turner
Nicholas J. Turner University of Manchester
Jason Micklefield
Jason Micklefield University of Manchester
Steven J. Plimpton
Steven J. Plimpton Sandia National Laboratories
William A. Goddard
William A. Goddard California Institute of Technology

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