World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
45
Citations
7383
World Ranking
16446
National Ranking
911

Overview

Helen C. Hailes is affiliated with University College London in the United Kingdom. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a total of 74 publications in this broad field.

The main subfields of Helen's work include molecular biology, organic chemistry, pharmacology, biomedical engineering, and pollution. The specific topics addressed in their research illustrate a concentration on enzyme catalysis and immobilization, microbial metabolic engineering and bioproduction, epigenetics and DNA methylation, chemical synthesis and analysis, microplastics and plastic pollution, cancer-related gene regulation, and chemical synthesis related to alkaloids.

Helen has published in several prominent scientific venues. Frequent publication outlets include:

  • ChemCatChem
  • ChemBioChem
  • RSC Advances
  • Advanced Synthesis & Catalysis
  • Green Chemistry

Coauthorship is a significant aspect of Helen's academic activity. Frequent collaborators include:

  • John M. Ward
  • Jack W. E. Jeffries
  • Fabiana Subrizi
  • Rebecca Roddan
  • Eve M. Carter

Helen's recent published papers reflect a range of biochemical topics and applications. Notable recent papers include:

  • "Methyltransferases: Functions and Applications," 2022, ChemBioChem
  • "Pictet-Spenglerases in alkaloid biosynthesis: Future applications in biocatalysis," 2020, Current Opinion in Chemical Biology
  • "The impact and effectiveness of the general public wearing masks to reduce the spread of pandemics in the UK: a multidisciplinary comparison of single-use masks versus reusable face masks," 2021, UCL Open Environment
  • "A bicyclic S-adenosylmethionine regeneration system applicable with different nucleosides or nucleotides as cofactor building blocks," 2021, RSC Chemical Biology
  • "Multienzyme One-Pot Cascades Incorporating Methyltransferases for the Strategic Diversification of Tetrahydroisoquinoline Alkaloids," 2021, Angewandte Chemie International Edition

Best Publications

  • Substrate spectrum of ω-transaminase from Chromobacterium violaceum DSM30191 and its potential for biocatalysis

    Ursula Kaulmann;Kirsty Smithies;Mark E.B. Smith;Helen C. Hailes

  • Reaction solvent selection : The potential of water as a solvent for organic transformations

    Helen C. Hailes

  • Two Steps in One Pot: Enzyme Cascade for the Synthesis of Nor(pseudo)ephedrine from Inexpensive Starting Materials

    Torsten Sehl;Helen C Hailes;John M Ward;Rainer Wardenga

  • One-pot synthesis of amino-alcohols using a de-novo transketolase and beta-alanine: pyruvate transaminase pathway in Escherichia coli.

    C.U. Ingram;M. Bommer;M.E.B. Smith;P.A. Dalby

  • Directed evolution of biocatalytic processes.

    Edward G. Hibbert;Frank Baganz;Helen C. Hailes;John M. Ward

  • Furfurylamines from biomass: transaminase catalysed upgrading of furfurals

    Alice Dunbabin;Fabiana Subrizi;John M. Ward;Tom D. Sheppard

  • Engineering stereoselectivity of ThDP‐dependent enzymes

    Helen C. Hailes;Dörte Rother;Michael Müller;Robert Westphal

  • Phosphate mediated biomimetic synthesis of tetrahydroisoquinoline alkaloids

    Thomas Pesnot;Markus C. Gershater;John M. Ward;Helen C. Hailes

  • Enzymatic and Chemoenzymatic Three-Step Cascades for the Synthesis of Stereochemically Complementary Trisubstituted Tetrahydroisoquinolines.

    Vanessa Erdmann;Benjamin R. Lichman;Jianxiong Zhao;Robert C. Simon

  • A Multidisciplinary Approach Toward the Rapid and Preparative-Scale Biocatalytic Synthesis of Chiral Amino Alcohols: A Concise Transketolase-/omega-Transaminase-Mediated Synthesis of (2S,3S)-2-Aminopentane-1,3-diol

    Mark E. B. Smith;Bing H. Chen;Edward G. Hibbert;Ursula Kaulmann

  • Enzyme catalysed Pictet-Spengler formation of chiral 1,1'-disubstituted- and spiro-tetrahydroisoquinolines.

    Benjamin R. Lichman;Jianxiong Zhao;Helen C. Hailes;John M. Ward

  • Incorporation of paramagnetic, fluorescent and PET/SPECT contrast agents into liposomes for multimodal imaging

    Nick Mitchell;Tammy L. Kalber;Margaret S. Cooper;Kavitha Sunassee

  • Directed evolution of transketolase activity on non-phosphorylated substrates

    Edward G. Hibbert;Tarik Senussi;Sean J. Costelloe;Wenling Lei

  • Efficient 2-step biocatalytic strategies for the synthesis of all nor(pseudo)ephedrine isomers

    Torsten Sehl;Helen C. Hailes;John M. Ward;Ulf Menyes

  • The Catalytic Potential of Coptis japonica NCS2 Revealed – Development and Utilisation of a Fluorescamine-Based Assay

    Thomas Pesnot;Markus C. Gershater;John M. Ward;Helen C. Hailes

  • Quadruply hydrogen bonded cytosine modules for supramolecular applications

    Valérie G.H. Lafitte;Abil E. Aliev;Peter N. Horton;Michael B. Hursthouse

  • Hydrophobic Polymers from Food Waste: Resources and Synthesis

    S. A. Sanchez-Vazquez;H. C. Hailes;J. R. G. Evans

  • Pictet-Spenglerases in alkaloid biosynthesis: Future applications in biocatalysis.

    Rebecca Roddan;John M. Ward;Nicholas H. Keep;Helen C. Hailes

  • Directed evolution of transketolase substrate specificity towards an aliphatic aldehyde.

    Edward G. Hibbert;Tarik Senussi;Mark E.B. Smith;Sean J. Costelloe

  • 'Dopamine-first' mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile

    Benjamin R. Lichman;Markus C. Gershater;Eleanor D. Lamming;Thomas Pesnot

  • Non-α-hydroxylated aldehydes with evolved transketolase enzymes

    Armando Cázares;James L. Galman;Lydia G. Crago;Mark E. B. Smith

Frequent Co-Authors

John M. Ward
John M. Ward University College London
John M. Woodley
John M. Woodley Technical University of Denmark
Martina Pohl
Martina Pohl Forschungszentrum Jülich
Tony Ng
Tony Ng King's College London
David E. Williams
David E. Williams University of Auckland
James Staunton
James Staunton University of Cambridge
Wolfgang Kroutil
Wolfgang Kroutil University of Graz
Jürgen Pleiss
Jürgen Pleiss University of Stuttgart
Michael Müller
Michael Müller Forschungszentrum Jülich
Peter F. Leadlay
Peter F. Leadlay University of Cambridge

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students pursuing Chemistry in the USA, exploring related fields such as forensic science and criminal justice can open diverse career opportunities. Many universities now offer flexible, affordable online programs that connect chemistry principles with real-world applications in law enforcement and psychology.

If you're interested in applying your chemistry knowledge to crime-solving, check out the best online colleges for forensic science. These programs provide specialized training in analyzing physical evidence using scientific methods.

For those leaning towards the behavioral side of investigations, an online masters forensic psychology degree offers advanced insights into criminal behavior and the psychological aspects of the legal system.

Understanding earning potential is crucial before choosing a career path. The forensic scientist salary varies widely based on experience, location, and education, highlighting the value of advanced degrees in boosting career growth.

Cost is another significant factor when pursuing these degrees. The cost of criminal justice degree programs varies across schools and formats but exploring affordable online options can make these career paths more accessible.

Best Scientists Citing Helen C. Hailes

Trending Scientists

Recently Published Articles