James Staunton

Research.com Recognitions

• 1998 - Fellow of the Royal Society, United Kingdom

Overview

Best Publications

• Polyketide biosynthesis: a millennium review.

  James Staunton;Kira J. Weissman

  2134
  Citations

• Disentangling electrospray spectra with maximum entropy

  A. G. Ferrige;M. J. Seddon;B. N. Green;S. A. Jarvis

  369
  Citations

• A chain initiation factor common to both modular and aromatic polyketide synthases

  Christian Bisang;Paul F. Long;Jesús Cortés;James Westcott

  364
  Citations

• Biosynthesis of Erythromycin and Rapamycin.

  James Staunton;Barrie Wilkinson

  353
  Citations

• Repositioning of a domain in a modular polyketide synthase to promote specific chain cleavage

  Jesus Cortes;Kirsten E. H. Wiesmann;Gareth A. Roberts;Murray J. B. Brown

  331
  Citations

• Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase

  Jesús F. Aparicio;István Molnár;Torsten Schwecke;Ariane König

  328
  Citations

• Engineering Broader Specificity into an Antibiotic-Producing Polyketide Synthase

  Andrew F. A. Marsden;Barrie Wilkinson;Jesús Cortés;Nicholas J. Dunster

  316
  Citations

• Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases

  Stephen F. Haydock;Jesús F. Aparicio;István Molnár;Torsten Schwecke

  296
  Citations

• A hybrid modular polyketide synthase obtained by domain swapping.

  Markiyan Oliynyk;Murray J.B. Brown;Jesús Cortés;James Staunton

  286
  Citations

• Maximum entropy signal processing in practical NMR spectroscopy

  Sibusiso Sibisi;John Skilling;Richard G. Brereton;Ernest D. Laue

  252
  Citations

• Role of type II thioesterases: evidence for removal of short acyl chains produced by aberrant decarboxylation of chain extender units.

  Michelle L Heathcote;James Staunton;Peter F Leadlay

  232
  Citations

• Stereospecific Acyl Transfers on the Erythromycin-Producing Polyketide Synthase

  Andrew F. A. Marsden;Patrick Caffrey;Jesus F. Aparicio;Mark S. Loughran

  216
  Citations

• Increasing the efficiency of heterologous promoters in actinomycetes.

  Christopher J Wilkinson;Zoë A Hughes-Thomas;Christine J Martin;Ines Böhm

  215
  Citations

• Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization

  Markiyan Oliynyk;Christian B. W. Stark;Apoorva Bhatt;Michelle A. Jones

  210
  Citations

• Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.

  István Molnár;Jesús F. Aparicio;Stephen F. Haydock;Lake Ee Khaw

  193
  Citations

• Identification of DEBS 1, DEBS 2 and DEBS 3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea.

  Patrick Caffrey;Debra J. Bevitt;James Staunton;Peter F. Leadlay

  180
  Citations

• Maximum entropy method in nuclear magnetic resonance spectroscopy

  Ernest D. Lade;John Skilling;James Staunton;Sibusiso Sibisi

  178
  Citations

• Evidence for a double-helical structure for modular polyketide synthases

  James Staunton;Patrick Caffrey;Jesús F. Aparicio;Gareth A. Roberts

  177
  Citations

• Active-site residue, domain and module swaps in modular polyketide synthases

  Francesca Del Vecchio;Hrvoje Petkovic;Steven G. Kendrew;Lindsey Low

  154
  Citations

• Mutational biosynthesis of novel rapamycins by a strain of Streptomyces hygroscopicus NRRL 5491 disrupted in rapL, encoding a putative lysine cyclodeaminase.

  Lake Ee Khaw;Günter A. Böhm;Su Metcalfe;James Staunton

  149
  Citations