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Chemistry

D-Index
82
Citations
24204
World Ranking
3087
National Ranking
172

Biology and Biochemistry

D-Index
82
Citations
24101
World Ranking
3698
National Ranking
276

Overview

Chris Abell is affiliated with the University of Cambridge in the United Kingdom. Their research spans multiple fields including Medicine and Biochemistry, Genetics and Molecular Biology, with particular focus in subfields such as Molecular Biology, Infectious Diseases, Biomedical Engineering, Epidemiology, and Materials Chemistry.

The scientist's work covers significant topics including Tuberculosis Research and Epidemiology, Biochemical and Molecular Research, Mycobacterium research and diagnosis, Enzyme Structure and Function, Neurological diseases and metabolism, Cancer therapeutics and mechanisms, and Innovative Microfluidic and Catalytic Techniques Innovation.

Among recent publications are:

  • "A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death," 2021, Cell chemical biology
  • "Spatially Controlled Supramolecular Polymerization of Peptide Nanotubes by Microfluidics," 2020, Angewandte Chemie International Edition
  • "Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission," 2022, Nature Communications
  • "Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors," 2020, Journal of Medicinal Chemistry
  • "Droplet-based microfluidic screening and sorting of microalgal populations for strain engineering applications," 2021, Algal Research

Frequent co-authors in their research include:

  • Anthony G. Coyne
  • Tom L. Blundell
  • V. Mendes
  • S.E. Thomas
  • Ziyi Yu

Chris Abell has published numerous articles in selected scientific venues, with a concentration in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Medicinal Chemistry
  • Angewandte Chemie International Edition
  • ACS Infectious Diseases
  • Angewandte Chemie

Best Publications

  • Small molecules, big targets: drug discovery faces the protein–protein interaction challenge

    Duncan Edward Scott;Andrew R Bayly;Andrew R Bayly;Christopher Abell;John Skidmore

  • Microdroplets in microfluidics: an evolving platform for discoveries in chemistry and biology

    Ashleigh B. Theberge;Fabienne Courtois;Yolanda Schaerli;Martin Fischlechner

  • High-throughput crystallography for lead discovery in drug design.

    Tom L. Blundell;Harren Jhoti;Chris Abell

  • Fragment-based approaches in drug discovery and chemical biology

    Duncan E. Scott;Anthony G. Coyne;Sean A. Hudson;Chris Abell

  • Tough Supramolecular Polymer Networks with Extreme Stretchability and Fast Room‐Temperature Self‐Healing

    Ji Liu;Cindy Soo Yun Tan;Cindy Soo Yun Tan;Ziyi Yu;Nan Li

  • One-step fabrication of supramolecular microcapsules from microfluidic droplets.

    Jing Zhang;Roger J. Coulston;Samuel T. Jones;Jin Geng

  • Static microdroplet arrays: a microfluidic device for droplet trapping, incubation and release for enzymatic and cell-based assays

    Ansgar Huebner;Dan Bratton;Graeme Whyte;Min Yang;Min Yang

  • Quantitative detection of protein expression in single cells using droplet microfluidics.

    A. Huebner;M. Srisa-Art;D. Holt;C. Abell

  • Continuous-Flow Polymerase Chain Reaction of Single-Copy DNA in Microfluidic Microdroplets

    Yolanda Schaerli;Robert C. Wootton;Tom Robinson;Viktor Stein

  • Chiral discrimination by chemical force microscopy

    Rachel McKendry;Maria-Elena Theoclitou;Trevor Rayment;Chris Abell

  • Surface-induced droplet fusion in microfluidic devices

    Luis M. Fidalgo;Chris Abell;Wilhelm T. S. Huck

  • Direct and sensitive detection of a human virus by rupture event scanning

    Matthew A. Cooper;Fedor N. Dultsev;Tony Minson;Victor P. Ostanin

  • Nanomechanical detection of antibiotic-mucopeptide binding in a model for superbug drug resistance.

    Joseph Wafula Ndieyira;Moyu Watari;Alejandra Donoso Barrera;Dejian Zhou;Dejian Zhou

  • Coupling microdroplet microreactors with mass spectrometry: reading the contents of single droplets online.

    Luis M Fidalgo;Graeme Whyte;Brandon T Ruotolo;Justin L P Benesch

  • Hydrophilic PDMS microchannels for high-throughput formation of oil-in-water microdroplets and water-in-oil-in-water double emulsions

    Wolfgang-Andreas C. Bauer;Martin Fischlechner;Chris Abell;Wilhelm T. S. Huck;Wilhelm T. S. Huck

  • Development of quantitative cell-based enzyme assays in microdroplets.

    Ansgar Huebner;Luis F. Olguin;Daniel Bratton;Graeme Whyte

  • Controlling the retention of small molecules in emulsion microdroplets for use in cell-based assays.

    Fabienne Courtois;Luis F. Olguin;Graeme Whyte;Ashleigh B. Theberge

  • A Reversible pH-Driven DNA Nanoswitch Array

    Dongsheng Liu;Andreas Bruckbauer;Chris Abell;Shankar Balasubramanian

  • Ultrarapid generation of femtoliter microfluidic droplets for single-molecule-counting immunoassays.

    Jung-uk Shim;Rohan T. Ranasinghe;Clive A. Smith;Shehu M. Ibrahim

  • Writing with DNA and protein using a nanopipet for controlled delivery.

    Andreas Bruckbauer;Liming Ying;Alison M. Rothery;Dejian Zhou

Frequent Co-Authors

Tom L. Blundell
Tom L. Blundell University of Cambridge
Alison G. Smith
Alison G. Smith University of Cambridge
Wilhelm T. S. Huck
Wilhelm T. S. Huck Radboud University
Oren A. Scherman
Oren A. Scherman University of Cambridge
John R. Coggins
John R. Coggins University of Glasgow
Alessio Ciulli
Alessio Ciulli University of Dundee
David Klenerman
David Klenerman University of Cambridge
Florian Hollfelder
Florian Hollfelder University of Cambridge
Dejian Zhou
Dejian Zhou University of Leeds
Shankar Balasubramanian
Shankar Balasubramanian University of Cambridge

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