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Chemistry

D-Index
99
Citations
29920
World Ranking
1362
National Ranking
525

Research.com Recognitions

  • 2013 - Fellow of the American Academy of Arts and Sciences
  • 2003 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1989 - Fellow of John Simon Guggenheim Memorial Foundation
  • 1985 - Ernest Guenther Award, American Chemical Society (ACS)
  • 1978 - Fellow of Alfred P. Sloan Foundation

Overview

David E. Cane is affiliated with Brown University in the United States. Their academic career includes recognition through several notable awards and fellowships highlighting contributions to the scientific community.

The awards received include:

  • Fellow of the American Academy of Arts and Sciences (2013)
  • Fellow of the American Association for the Advancement of Science (AAAS) (2003)
  • Fellow of John Simon Guggenheim Memorial Foundation (1989)
  • Ernest Guenther Award, American Chemical Society (ACS) (1985)
  • Fellow of Alfred P. Sloan Foundation (1978)

These honors reflect involvement and distinction in scientific research and academia over several decades.

While specific details on publications, co-authors, fields of study, subfields, and main research topics are not provided, the scholar's association with Brown University and these recognitions position them within a context of scientific research and academic engagement at a national and international level.

Best Publications

  • Biosynthesis of Complex Polyketides in a Metabolically Engineered Strain of E. coli

    Blaine A. Pfeifer;Suzanne J. Admiraal;Hugo Gramajo;David E. Cane

  • Harnessing the Biosynthetic Code: Combinations, Permutations, and Mutations

    David E. Cane;Christopher T. Walsh;Chaitan Khosla

  • Enzymic formation of sesquiterpenes

    David E. Cane

  • Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

    Mamoru Komatsu;Takuma Uchiyama;Satoshi Omura;David E. Cane

  • Terpene synthases are widely distributed in bacteria

    Yuuki Yamada;Tomohisa Kuzuyama;Mamoru Komatsu;Kazuo Shin-ya

  • Crystal structure of pentalenene synthase: Mechanistic insights on terpenoid cyclization reactions in biology

    Charles A. Lesburg;Guangzhi Zhai;Guangzhi Zhai;David E. Cane;David E. Cane;David W. Christianson;David W. Christianson

  • TOLERANCE AND SPECIFICITY OF POLYKETIDE SYNTHASES

    Chaitan Khosla;Rajesh S. Gokhale;John R. Jacobsen;David E. Cane

  • Dissecting and exploiting intermodular communication in polyketide synthases.

    Rajesh S. Gokhale;Stuart Y. Tsuji;David E. Cane;Chaitan Khosla

  • The parallel and convergent universes of polyketide synthases and nonribosomal peptide synthetases.

    David E Cane;Christopher T Walsh

  • Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase.

    John R. Jacobsen;C. Richard Hutchinson;David E. Cane;Chaitan Khosla

  • Biosynthetic origin of the carbon skeleton and oxygen atoms of nargenicin A1

    David E. Cane;Chi Ching Yang

  • Structure and Mechanism of the 6-Deoxyerythronolide B Synthase

    Chaitan Khosla;Yinyan Tang;Alice Y. Chen;Nathan A. Schnarr

  • The 2.7-Å crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase

    Yinyan Tang;Chu-Young Kim;Irimpan I. Mathews;David E. Cane

  • Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade.

    Michael J. Rynkiewicz;David E. Cane;David W. Christianson

  • Unified stereochemical model of polyether antibiotic structure and biogenesis

    David E. Cane;Walter D. Celmer;John W. Westley

  • Biosynthesis of the earthy odorant geosmin by a bifunctional Streptomyces coelicolor enzyme

    Jiaoyang Jiang;Xiaofei He;David E Cane

  • Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolites

    Mamoru Komatsu;Kyoko Komatsu;Hanae Koiwai;Yuuki Yamada

  • Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel

    Shiou-Chuan Tsai;Larry J. W. Miercke;Jolanta Krucinski;Rajesh Gokhale

  • Manipulation of macrolide ring size by directed mutagenesis of a modular polyketide synthase

    Camilla M. Kao;Guanglin Luo;Leonard Katz;David E. Cane

  • Exploration and mining of the bacterial terpenome.

    David E. Cane;Haruo Ikeda

  • Crystal structure determination of aristolochene synthase from the blue cheese mold, Penicillium roqueforti.

    Jonathan M. Caruthers;Ilgu Kang;Michael J. Rynkiewicz;David E. Cane

Frequent Co-Authors

Chaitan Khosla
Chaitan Khosla Stanford University
David W. Christianson
David W. Christianson University of Pennsylvania
Haruo Ikeda
Haruo Ikeda Kitasato University
Rodney Croteau
Rodney Croteau Washington State University
Satoshi Omura
Satoshi Omura Kitasato University
Zixin Deng
Zixin Deng Shanghai Jiao Tong University
E. J. Corey
E. J. Corey Harvard University
Christopher T. Walsh
Christopher T. Walsh Stanford University
Chris Abell
Chris Abell University of Cambridge
Leonard Katz
Leonard Katz Haskins Laboratories

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