2013 - Fellow of the American Academy of Arts and Sciences
2003 - Fellow of the American Association for the Advancement of Science (AAAS)
1989 - Fellow of John Simon Guggenheim Memorial Foundation
1985 - Ernest Guenther Award, American Chemical Society (ACS)
1978 - Fellow of Alfred P. Sloan Foundation
His primary areas of investigation include Stereochemistry, Biochemistry, Biosynthesis, Polyketide and Polyketide synthase. The Stereochemistry study combines topics in areas such as Active site, ATP synthase, Enzyme, Protein structure and Acyl carrier protein. His work deals with themes such as Streptomycetaceae and Streptomyces, which intersect with Biochemistry.
His Biosynthesis research incorporates elements of Sesquiterpene and Antibacterial agent, Bacteria. Protein domain and Cell biology is closely connected to Protein engineering in his research, which is encompassed under the umbrella topic of Polyketide. David E. Cane combines subjects such as Lactone, Polyketide biosynthesis, Multifunctional Enzymes, Protein–protein interaction and Saccharopolyspora erythraea with his study of Polyketide synthase.
The scientist’s investigation covers issues in Stereochemistry, Biochemistry, Biosynthesis, Polyketide and ATP synthase. David E. Cane interconnects Polyketide synthase and Active site, Substrate, Enzyme in the investigation of issues within Stereochemistry. Biochemistry and Streptomyces are commonly linked in his work.
His Biosynthesis research is multidisciplinary, incorporating perspectives in Bacteria, Streptomycetaceae, Actinomycetales and Pyrophosphate. His Polyketide study combines topics in areas such as Protein structure, Thioester, Protein engineering and Acyl carrier protein. The ATP synthase study combines topics in areas such as Streptomyces coelicolor, Recombinant DNA and Stereoisomerism.
His scientific interests lie mostly in Stereochemistry, Biochemistry, ATP synthase, Polyketide and Polyketide synthase. His work carried out in the field of Stereochemistry brings together such families of science as Stereoisomerism, Lyase, Active site, Substrate and Acyl carrier protein. His study focuses on the intersection of Biochemistry and fields such as Streptomyces with connections in the field of Heterologous expression, Gene and Complementation.
His ATP synthase research incorporates elements of Sesquiterpene, Streptomyces coelicolor, Transferase and Terpenoid. In the field of Polyketide, his study on 6-Deoxyerythronolide B synthase overlaps with subjects such as Assembly line. His Polyketide synthase study integrates concerns from other disciplines, such as Molecular recognition, Nonribosomal peptide and Docking.
David E. Cane mostly deals with Stereochemistry, Biochemistry, ATP synthase, Polyketide and Streptomyces. His Stereochemistry study focuses on Natural product in particular. His Biochemistry study focuses mostly on Biosynthesis, Protein structure, Terpene, Terpenoid and Monooxygenase.
His ATP synthase research includes elements of Protein engineering, Acyl carrier protein and Stereoisomerism. In general Polyketide study, his work on Polyketide synthase and 6-Deoxyerythronolide B synthase often relates to the realm of Assembly line and Mechanism, thereby connecting several areas of interest. His Streptomyces study combines topics in areas such as Heterologous expression and Escherichia coli.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Biosynthesis of Complex Polyketides in a Metabolically Engineered Strain of E. coli
Blaine A. Pfeifer;Suzanne J. Admiraal;Hugo Gramajo;David E. Cane.
Science (2001)
Harnessing the Biosynthetic Code: Combinations, Permutations, and Mutations
David E. Cane;Christopher T. Walsh;Chaitan Khosla.
Science (1998)
Enzymic formation of sesquiterpenes
David E. Cane.
Chemical Reviews (1990)
Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism
Mamoru Komatsu;Takuma Uchiyama;Satoshi Omura;David E. Cane.
Proceedings of the National Academy of Sciences of the United States of America (2010)
Crystal structure of pentalenene synthase: Mechanistic insights on terpenoid cyclization reactions in biology
Charles A. Lesburg;Guangzhi Zhai;Guangzhi Zhai;David E. Cane;David E. Cane;David W. Christianson;David W. Christianson.
Science (1997)
TOLERANCE AND SPECIFICITY OF POLYKETIDE SYNTHASES
Chaitan Khosla;Rajesh S. Gokhale;John R. Jacobsen;David E. Cane.
Annual Review of Biochemistry (1999)
Dissecting and exploiting intermodular communication in polyketide synthases.
Rajesh S. Gokhale;Stuart Y. Tsuji;David E. Cane;Chaitan Khosla.
Science (1999)
Terpene synthases are widely distributed in bacteria
Yuuki Yamada;Tomohisa Kuzuyama;Mamoru Komatsu;Kazuo Shin-ya.
Proceedings of the National Academy of Sciences of the United States of America (2015)
The parallel and convergent universes of polyketide synthases and nonribosomal peptide synthetases.
David E Cane;Christopher T Walsh.
Chemistry & Biology (1999)
Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase.
John R. Jacobsen;C. Richard Hutchinson;David E. Cane;Chaitan Khosla.
Science (1997)
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