D-Index & Metrics Best Publications
Chemistry
Japan
2023
Biology and Biochemistry
Japan
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 95 Citations 38,478 1,022 World Ranking 886 National Ranking 43
Biology and Biochemistry D-index 100 Citations 44,222 1,113 World Ranking 1003 National Ranking 56

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in Japan Leader Award

2023 - Research.com Chemistry in Japan Leader Award

2015 - Nobel Prize for their discoveries concerning a novel therapy against infections caused by roundworm parasites

2010 - Tetrahedron Prize for Creativity in Organic Chemistry or Bioorganic and Medicinal Chemistry, Elsevier

2005 - Member of the European Academy of Sciences

2005 - Ernest Guenther Award, American Chemical Society (ACS)

2000 - Nakanishi Prize, Chemical Society of Japan and the American Chemical Society.

1999 - Member of the National Academy of Sciences

1997 - Prince Mahidol Award

1997 - Robert Koch Gold Medal

1992 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Microbiology and Immunology

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Biochemistry
  • Gene

His main research concerns Biochemistry, Streptomyces, Stereochemistry, Microbiology and Antibiotics. His Biochemistry study is mostly concerned with Enzyme, Sterol O-acyltransferase, Biological activity, Enzyme inhibitor and Fermentation. His biological study spans a wide range of topics, including Heterologous expression and Biosynthesis.

He frequently studies issues relating to Amino acid and Stereochemistry. His study looks at the intersection of Microbiology and topics like Bacteria with Antimicrobial and Isolation. His Streptomyces avermitilis study integrates concerns from other disciplines, such as Secondary metabolism and Mutant, Streptomyces coelicolor.

His most cited work include:

  • Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis (1017 citations)
  • Avermectins, New Family of Potent Anthelmintic Agents: Producing Organism and Fermentation (686 citations)
  • Genome sequence of an industrial microorganism Streptomyces avermitilis: Deducing the ability of producing secondary metabolites (680 citations)

What are the main themes of his work throughout his whole career to date?

Satoshi Omura spends much of his time researching Stereochemistry, Biochemistry, Microbiology, Antibiotics and Streptomyces. His Stereochemistry study frequently draws parallels with other fields, such as Penicillium. His Biochemistry and Enzyme, Biosynthesis, Biological activity, Enzyme inhibitor and Fermentation investigations all form part of his Biochemistry research activities.

The subject of his Biological activity research is within the realm of In vitro. His research investigates the link between Microbiology and topics such as Bacteria that cross with problems in Antimicrobial. His is involved in several facets of Streptomyces study, as is seen by his studies on Streptomycetaceae, Actinomycetales and Streptomyces avermitilis.

He most often published in these fields:

  • Stereochemistry (34.45%)
  • Biochemistry (29.12%)
  • Microbiology (20.67%)

What were the highlights of his more recent work (between 2005-2021)?

  • Stereochemistry (34.45%)
  • Microbiology (20.67%)
  • Biochemistry (29.12%)

In recent papers he was focusing on the following fields of study:

Stereochemistry, Microbiology, Biochemistry, Total synthesis and Antibiotics are his primary areas of study. His Stereochemistry research is multidisciplinary, incorporating elements of Cyclic peptide, Structure–activity relationship, Chemical synthesis and Stereoselectivity. His studies deal with areas such as Peptidoglycan, 16S ribosomal RNA, Bacteria, Penicillium and Taxonomy as well as Microbiology.

His study brings together the fields of Streptomyces and Biochemistry. He has researched Streptomyces in several fields, including Type three secretion system and Biosynthesis. In his work, Mitemcinal and Cytotoxicity is strongly intertwined with Pharmacology, which is a subfield of Antibiotics.

Between 2005 and 2021, his most popular works were:

  • Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism (355 citations)
  • Terpene synthases are widely distributed in bacteria (235 citations)
  • Structural and Computational Analysis of the Quinone-binding Site of Complex II (Succinate-Ubiquinone Oxidoreductase) A MECHANISM OF ELECTRON TRANSFER AND PROTON CONDUCTION DURING UBIQUINONE REDUCTION (188 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Biochemistry

Satoshi Omura mostly deals with Stereochemistry, Biochemistry, Microbiology, Streptomyces and Streptomyces avermitilis. His Stereochemistry research includes themes of Combinatorial chemistry, Chemical synthesis and Stereoisomerism. His work deals with themes such as Verticillium sp. and Ascaris suum, which intersect with Biochemistry.

His work on Antibiotics as part of general Microbiology study is frequently connected to Mycobacterium smegmatis, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. The Streptomyces study combines topics in areas such as Antiparasitic, Type three secretion system, Heterologous expression and Biosynthesis. His Streptomyces avermitilis research is multidisciplinary, incorporating perspectives in Oxidoreductase and Gene cluster, Gene, Dioxygenase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis

Haruo Ikeda;Jun Ishikawa;Akiharu Hanamoto;Mayumi Shinose.
Nature Biotechnology (2003)

1551 Citations

Avermectins, New Family of Potent Anthelmintic Agents: Producing Organism and Fermentation

R W Burg;B M Miller;E E Baker;J Birnbaum.
Antimicrobial Agents and Chemotherapy (1979)

1157 Citations

Genome sequence of an industrial microorganism Streptomyces avermitilis: Deducing the ability of producing secondary metabolites

Satoshi Omura;Haruo Ikeda;Jun Ishikawa;Akiharu Hanamoto.
Proceedings of the National Academy of Sciences of the United States of America (2001)

991 Citations

A NEW ALKALOID AM-2282 OF STREPTOMYCES ORIGIN TAXONOMY, FERMENTATION, ISOLATION AND PRELIMINARY CHARACTERIZATION

Satoshi Omura;Yuzuru Iwai;Atsushi Hirano;Akira Nakagawa.
The Journal of Antibiotics (1977)

883 Citations

Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells.

Satoshi Omura;Tomoko Fujimoto;Kazuhiko Otoguro;Keiichi Matsuzaki.
The Journal of Antibiotics (1991)

705 Citations

The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2.

Takenobu Katagiri;Akira Yamaguchi;Tohru Ikeda;Shusaku Yoshiki.
Biochemical and Biophysical Research Communications (1990)

610 Citations

Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

Mamoru Komatsu;Takuma Uchiyama;Satoshi Omura;David E. Cane.
Proceedings of the National Academy of Sciences of the United States of America (2010)

541 Citations

Production of 'hybrid' antibiotics by genetic engineering.

D. A. Hopwood;F. Malpartida;H. M. Kieser;H. Ikeda.
Nature (1985)

465 Citations

ORGANIZATION OF THE BIOSYNTHETIC GENE CLUSTER FOR THE POLYKETIDE ANTHELMINTIC MACROLIDE AVERMECTIN IN STREPTOMYCES AVERMITILIS

Haruo Ikeda;Tomoko Nonomiya;Masayo Usami;Toshio Ohta.
Proceedings of the National Academy of Sciences of the United States of America (1999)

437 Citations

Degradation of a Mutant Secretory Protein, α1-Antitrypsin Z, in the Endoplasmic Reticulum Requires Proteasome Activity

Dongfeng Qu;Jeffrey H. Teckman;Satoshi Omura;David H. Perlmutter.
Journal of Biological Chemistry (1996)

412 Citations

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