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Hiroshi Tomoda

Hiroshi Tomoda

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
14302
World Ranking
9200
National Ranking
617

Overview

Hiroshi Tomoda is affiliated with Kitasato University in Japan. Their research is primarily focused on fields such as Medicine and Biochemistry, Genetics and Molecular Biology, with substantial contributions also in the subfields of Pharmacology, Molecular Biology, Organic Chemistry, Epidemiology, and Small Animals.

The scientist's work covers key topics including:

  • Microbial Natural Products and Biosynthesis
  • Mycobacterium research and diagnosis
  • Infectious Diseases and Mycology
  • Fungal Biology and Applications
  • Heterotopic Ossification and Related Conditions
  • Antifungal resistance and susceptibility
  • Marine Sponges and Natural Products

Frequent publication venues for Hiroshi Tomoda include:

  • The Journal of Antibiotics (16 publications)
  • Bioorganic & Medicinal Chemistry Letters (4 publications)
  • Drug Discoveries & Therapeutics (3 publications)
  • Molecules (2 publications)
  • Organic Letters (2 publications)

Notable recent papers authored by or involving the scientist are:

  • "Evaluation of Anti-Mycobacterial Compounds in a Silkworm Infection Model with Mycobacteroides abscessus" (2020, Molecules)
  • "Polyketide glycosides phialotides A to H, new potentiators of amphotericin B activity, produced by Pseudophialophora sp. BF-0158" (2020, The Journal of Antibiotics)
  • "A new diketopiperazine-like inhibitor of bone morphogenetic protein-induced osteoblastic differentiation produced by marine-derived Aspergillus sp. BFM-0085" (2020, The Journal of Antibiotics)
  • "Synthesis and Absolute Configuration of Habiterpenol" (2020, Organic Letters)
  • "Development of an in vivo-mimic silkworm infection model with Mycobacterium avium complex" (2020, Drug Discoveries & Therapeutics)

The scientist has collaborated frequently with colleagues including Taichi Ohshiro, Ryuji Uchida, Keisuke Kobayashi, Satoshi Ohte, and Kenichiro Nagai, with collaboration counts ranging from 9 to 22 coauthored works.

Best Publications

  • Atpenins, potent and specific inhibitors of mitochondrial complex II (succinate-ubiquinone oxidoreductase)

    Hiroko Miyadera;Kazuro Shiomi;Hideaki Ui;Yuichi Yamaguchi

  • Lysocin E is a new antibiotic that targets menaquinone in the bacterial membrane

    Hiroshi Hamamoto;Makoto Urai;Makoto Urai;Kenichi Ishii;Jyunichiro Yasukawa

  • ACAT2 Is Localized to Hepatocytes and Is the Major Cholesterol-Esterifying Enzyme in Human Liver

    Paolo Parini;Matthew Davis;Aaron T. Lada;Sandra K. Erickson

  • Binding site of cerulenin in fatty acid synthetase.

    Hiroshi Funabashi;Akihiko Kawaguchi;Hiroshi Tomoda;Satoshi Ömura

  • Inhibition of acyl-CoA: cholesterol acyltransferase activity by cyclodepsipeptide antibiotics.

    Hiroshi Tomoda;Xin-Hui Huang;Jin Caoa;Hiroyuki Nishida

  • Pyripyropenes, highly potent inhibitors of acyl-CoA:cholesterol acyltransferase produced by Aspergillus fumigatus.

    Satoshi Omura;Hiroshi Tomoda;Young Kook Kim;Hiroyuki Nishida

  • Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva

    Toru Fukuda;Masakazu Kohda;Kazuhiro Kanomata;Junya Nojima

  • Inhibition of acyl-CoA synthetase by triacsins

    H Tomoda;K Igarashi;S Omura

  • Evidence for an essential role of long chain acyl-CoA synthetase in animal cell proliferation. Inhibition of long chain acyl-CoA synthetase by triacsins caused inhibition of Raji cell proliferation.

    H. Tomoda;K. Igarashi;Jong-Chol Cyong;S. Omura

  • Xanthohumols, diacylglycerol acyltransferase inhibitors, from Humulus lupulus

    Noriko Tabata;Minako Ito;Hiroshi Tomoda;Satoshi Ōmura

  • Lariatins, antimycobacterial peptides produced by Rhodococcus sp. K01-B0171, have a lasso structure.

    Masato Iwatsuki;Hiroshi Tomoda;Ryuji Uchida;Hiroaki Gouda

  • Pyripyropenes, novel inhibitors of acyl-CoA:cholesterol acyltransferase produced by Aspergillus fumigatus. I. Production, isolation, and biological properties.

    Hiroshi Tomoda;Young Kook Kim;Hiroyuki Nishida;Rokuro Masuma

  • Identification of ACAT1- and ACAT2-specific inhibitors using a novel, cell-based fluorescence assay: individual ACAT uniqueness.

    Aaron T. Lada;Matthew Davis;Carol Kent;James Chapman

  • p53-Defective Tumors With a Functional Apoptosome-Mediated Pathway: A New Therapeutic Target

    Tetsuo Mashima;Tomoko Oh-hara;Shigeo Sato;Mikiko Mochizuki

  • Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages.

    Tadayoshi Karasawa;Akira Kawashima;Fumitake Usui-Kawanishi;Sachiko Watanabe

  • Yaequinolones J1 and J2, novel insecticidal antibiotics from Penicillium sp. FKI-2140.

    Ryuji Uchida;Rie Imasato;Kazuro Shiomi;Hiroshi Tomoda

  • PYRIPYROPENES, NOVEL INHIBITORS OF ACYL-CoA: CHOLESTEROL ACYLTRANSFERASE PRODUCED BY Aspergillus fumigatus II. STRUCTURE ELUCIDATION OF PYRIPYROPENES A, B, C AND D

    Young Kook Kim;Hiroshi Tomoda;Hiroyuki Nishida;Toshiaki Sunazuka

  • Antiatherogenic activity of fungal beauveriolides, inhibitors of lipid droplet accumulation in macrophages.

    Ichiji Namatame;Hiroshi Tomoda;Shun Ishibashi;Satoshi Omura

  • Selectivity of Microbial Acyl-CoA : cholesterol Acyltransferase Inhibitors toward Isozymes

    Taichi Ohshiro;Lawrence L Rudel;Satoshi Omura;Hiroshi Tomoda

  • Inhibition of tyrosinase activity and melanine pigmentation by 2-hydroxytyrosol

    Ryuji Uchida;Seiko Ishikawa;Hiroshi Tomoda

Frequent Co-Authors

Satoshi Omura
Satoshi Omura Kitasato University
Kazuro Shiomi
Kazuro Shiomi Kitasato University
Lawrence L. Rudel
Lawrence L. Rudel Wake Forest University
Takashi Takahashi
Takashi Takahashi Nagoya University
Kiyoshi Kita
Kiyoshi Kita Nagasaki University
Shun Ishibashi
Shun Ishibashi Jichi Medical University
Yutaka Ebizuka
Yutaka Ebizuka University of Tokyo
Haruo Ikeda
Haruo Ikeda Kitasato University
Hideyuki Shigemori
Hideyuki Shigemori University of Tsukuba
Hirokazu Kawagishi
Hirokazu Kawagishi Shizuoka University

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