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Hideyuki Shigemori

Hideyuki Shigemori

D-Index & Metrics

Chemistry

D-Index
50
Citations
7492
World Ranking
14544
National Ranking
1135

Overview

Hideyuki Shigemori is affiliated with the University of Tsukuba in Japan. Their research spans several fields, primarily focusing on medicine, biochemistry, genetics, and molecular biology. Within these broad fields, Shigemori has contributed substantially to subfields including molecular biology, physiology, plant science, pharmacology, and endocrinology related to diabetes and metabolism.

The core topics of Shigemori's work include Alzheimer's disease research and treatments, natural antidiabetic agent studies, and investigations on bioactive compounds derived from seaweed. Additional areas of focus involve phytochemicals and antioxidant activities, advanced glycation end products research, phytoestrogen effects, and biochemical effects in animals.

Shigemori's recent publications reflect this focus and include the following papers:

  • Inhibitory activities of phenylpropanoids from Lycopus lucidus on amyloid aggregation related to Alzheimer's disease and type 2 diabetes (2020), Journal of Natural Medicines
  • Evaluation of Amyloid Polypeptide Aggregation Inhibition and Disaggregation Activity of A-Type Procyanidins (2021), Pharmaceuticals
  • Effects of clovamide and its related compounds on the aggregations of amyloid polypeptides (2021), Journal of Natural Medicines
  • Three new meroterpenoids from Sargassum macrocarpum and their inhibitory activity against amyloid β aggregation (2023), Journal of Natural Medicines
  • Combinational Anti-tumor Effects of Chemicals from Paeonia lutea Leaf Extract in Oral Squamous Cell Carcinoma Cells (2021), Anticancer Research

Frequent coauthors in Shigemori's body of work include Yusaku Miyamae, Yuta Tozawa, Mitsuhiro Sekiguchi, Taisei Tanaka, and Vipul V. Betkekar.

Shigemori often publishes in the Journal of Natural Medicines and has multiple publications in other scientific venues such as Biological and Pharmaceutical Bulletin, Bioscience Biotechnology and Biochemistry, Tetrahedron Letters, and ACS Chemical Biology.

Best Publications

  • Purealidins B and C, new bromotyrosine alkaloids from the okinawan marine sponge psammaplysilla purea

    Jun'ichi Kobayashi;Masashi Tsuda;Kaori Agemi;Hideyuki Shigemori

  • Alteramide A, a new tetracyclic alkaloid from a bacterium Alteromonas sp. associated with the marine sponge Halichondria okadai

    Hideyuki Shigemori;Myung Ae Bae;Kazunaga Yazawa;Takuma Sasaki

  • Ircinals A and B from the Okinawan marine sponge Ircinia sp.: plausible biogenetic precursors of manzamine alkaloids

    Kazuhiko Kondo;Hideyuki Shigemori;Yumiko Kikuchi;Masami Ishibashi

  • MANZACIDINS A-C, NOVEL TETRAHYDROPYRIMIDINE ALKALOIDS FROM THE OKINAWAN MARINE SPONGE HYMENIACIDON SP.

    Junichi Kobayashi;Fuyuko Kanda;Masami Ishibashi;Hideyuki Shigemori

  • Neuroprotective effect of 3,5-di-O-caffeoylquinic acid on SH-SY5Y cells and senescence-accelerated-prone mice 8 through the up-regulation of phosphoglycerate kinase-1.

    J. Han;Y. Miyamae;H. Shigemori;H. Isoda

  • Taxuspines A ∼ C, new taxoids from Japanese yew Taxus cuspidata inhibiting drug transport activity of P-glycoprotein in multidrug-resistant cells

    Juníchi Kobayashi;Aya Ogiwara;Hirokazu Hosoyama;Hideyuki Shigemori

  • Brasilicardin A, a novel tricyclic metabolite with potent immunosuppressive activity from actinomycete Nocardia brasiliensis

    Hideyuki Shigemori;Hisayuki Komaki;Katsukiyo Yazawa;Yuzuru Mikami

  • Naucleamides A-E, new monoterpene indole alkaloids from Nauclea latifolia.

    Hideyuki Shigemori;Toshinori Kagata;Haruaki Ishiyama;Frank Morah

  • Fellutamides A and B, cytotoxic peptides from a marine fish-possessing fungus Penicillium fellutanum

    Hideyuki Shigemori;Shinobu Wakuri;Kazunaga Yazawa;Takemichi Nakamura

  • Oxylipins arabidopsides C and D from Arabidopsis thaliana.

    Yosuke Hisamatsu;Nobuharu Goto;Mitsuhiro Sekiguchi;Koji Hasegawa

  • Antimitotic activity of moroidin, a bicyclic peptide from the seeds of Celosia argentea.

    Hiroshi Morita;Kazutaka Shimbo;Hideyuki Shigemori;Jun'ichi Kobayashi

  • Arabidopsides A and B, two new oxylipins from Arabidopsis thaliana

    Yosuke Hisamatsu;Nobuharu Goto;Koji Hasegawa;Hideyuki Shigemori

  • Paratunamides A-D, oxindole alkaloids from Cinnamodendron axillare.

    Toshinori Kagata;Shizuka Saito;Hideyuki Shigemori;Ayumi Ohsaki

  • Growth inhibitory alkaloids from mesquite (Prosopis juliflora (Sw.) DC.) leaves

    Hiroshi Nakano;Eri Nakajima;Syuntaro Hiradate;Yoshiharu Fujii

  • Amphidinolides G and H: new potent cytotoxic macrolides from the cultured symbiotic dinoflagellate Amphidinium sp

    Junichi Kobayashi;Hideyuki Shigemori;Masami Ishibashi;Terufumi Yamasu

  • Hymenamides a and b, new proline-rich cyclic heptapeptides from the okinawan marine sponge hymeniacidon sp.

    Jun'ichi Kobayashi;Masashi Tsuda;Takemichi Nakamura;Yuzuru Mikami;Yuzuru Mikami

  • Subincanadines A-C, novel quaternary indole alkaloids from Aspidosperma subincanum.

    Jun'ichi Kobayashi;Mitsuhiro Sekiguchi;Sayaka Shimamoto;Hideyuki Shigemori

  • Nakijiquinones C and D, new sesquiterpenoid quinones with a hydroxy amino acid residue from a marine sponge inhibiting c-erbB-2 kinase

    Jun'ichi Kobayashi;Tatsushi Madono;Hideyuki Shigemori

  • Keramamides B .apprx. D, novel peptides from the Okinawan marine sponge Theonella sp

    Junichi Kobayashi;Fumio Itagaki;Hideyuki Shigemori;Masami Ishibashi

  • Purealidins J-R, new bromotyrosine alkaloids from the Okinawan marine sponge Psammaplysilla purea

    Jun'ichi Kobayashi;Kaori Honma;Takuma Sasaki;Masashi Tsuda

  • Structure-activity relationship of caffeoylquinic acids on the accelerating activity on ATP production.

    Yusaku Miyamae;Manami Kurisu;Junkyu Han;Hiroko Isoda

Frequent Co-Authors

Jun'ichi Kobayashi
Jun'ichi Kobayashi Hokkaido University
Masami Ishibashi
Masami Ishibashi Chiba University
Yuzuru Mikami
Yuzuru Mikami Chiba University
Masashi Tsuda
Masashi Tsuda Kōchi University
Takashi Tsuruo
Takashi Tsuruo Japanese Foundation For Cancer Research
Motoo Shiro
Motoo Shiro Nagoya Institute of Technology
Hiroshi Tomoda
Hiroshi Tomoda Kitasato University
Toshifumi Takao
Toshifumi Takao Osaka University
Mikihiko Naito
Mikihiko Naito University of Tokyo
Tsuyoshi Hasegawa
Tsuyoshi Hasegawa Waseda University

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