What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Cell biology, Biochemistry, Apoptosis, Molecular biology and P-glycoprotein.
His research integrates issues of Inhibitor of apoptosis, Cancer therapy, Ubiquitin and Mutagenesis in his study of Cell biology.
His Biochemistry course of study focuses on Biophysics and Intracellular.
His Apoptosis research is multidisciplinary, incorporating elements of Proteases, Cancer research and Protease.
The various areas that Mikihiko Naito examines in his Molecular biology study include Receptor, Phosphoprotein, Cell fractionation and Transfection.
His research in P-glycoprotein intersects with topics in Endothelial stem cell, Vasculogenesis, Blood–brain barrier and Pharmacology.
His most cited work include:
- Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal. (406 citations)
- Functional involvement of P-glycoprotein in blood-brain barrier (313 citations)
- Brain pericytes contribute to the induction and up-regulation of blood–brain barrier functions through transforming growth factor-β production (251 citations)
What are the main themes of his work throughout his whole career to date?
Mikihiko Naito mainly focuses on Cell biology, Biochemistry, Molecular biology, Cancer research and Pharmacology.
His Cell biology research integrates issues from Ubiquitin, Ubiquitin ligase, Downregulation and upregulation and Cytosol.
He works mostly in the field of Biochemistry, limiting it down to topics relating to Biophysics and, in certain cases, Intracellular, as a part of the same area of interest.
As a part of the same scientific family, Mikihiko Naito mostly works in the field of Molecular biology, focusing on Apoptosis and, on occasion, Proteases, Cancer cell, Monocytic leukemia and Tumor necrosis factor alpha.
Mikihiko Naito interconnects P-glycoprotein, Multiple drug resistance and Cyclosporin a in the investigation of issues within Pharmacology.
His research in P-glycoprotein tackles topics such as Blood–brain barrier which are related to areas like Endothelial stem cell and Endothelium.
He most often published in these fields:
- Cell biology (25.00%)
- Biochemistry (25.00%)
- Molecular biology (20.76%)
What were the highlights of his more recent work (between 2016-2021)?
- Cell biology (25.00%)
- Protein degradation (7.20%)
- Ubiquitin ligase (8.90%)
In recent papers he was focusing on the following fields of study:
Mikihiko Naito spends much of his time researching Cell biology, Protein degradation, Ubiquitin ligase, Inhibitor of apoptosis and Biochemistry.
His Cell biology study combines topics from a wide range of disciplines, such as Ubiquitin, Cytosol, Estrogen receptor, Philadelphia chromosome and Mitophagy.
His work in Ubiquitin covers topics such as Androgen receptor which are related to areas like Protein–protein interaction, Coactivator and Molecular biology.
His studies deal with areas such as Gene knockdown, Target protein and Drug discovery as well as Ubiquitin ligase.
His research on Inhibitor of apoptosis concerns the broader Apoptosis.
Mikihiko Naito undertakes multidisciplinary investigations into Biochemistry and Amphiphile in his work.
Between 2016 and 2021, his most popular works were:
- In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs). (96 citations)
- Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands (63 citations)
- Development of protein degradation inducers of oncogenic BCR‐ABL protein by conjugation of ABL kinase inhibitors and IAP ligands (39 citations)
In his most recent research, the most cited papers focused on:
His primary scientific interests are in XIAP, Inhibitor of apoptosis, Cell biology, Ubiquitin and Protein degradation.
Mikihiko Naito combines subjects such as Cancer cell, Chronic myelogenous leukemia, Cancer research and Ubiquitin ligase with his study of XIAP.
Ubiquitin ligase is a subfield of Biochemistry that he investigates.
His Inhibitor of apoptosis study contributes to a more complete understanding of Apoptosis.
He has researched Apoptosis in several fields, including Protein ligand, Receptor, Molecular biology and Prostate cancer, Androgen receptor.
His work carried out in the field of Cell biology brings together such families of science as Autophagy and ATG8.
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