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Mikihiko Naito

Mikihiko Naito

University of Tokyo
Japan

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
16383
World Ranking
6388
National Ranking
413

Mikihiko Naito publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Mikihiko Naito sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 278 publications — 74th percentile

74% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Mikihiko Naito D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Mikihiko Naito sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 72 D-Index — 69th percentile

69% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Mikihiko Naito is affiliated with the University of Tokyo in Japan and has made contributions primarily in the fields of Biochemistry, Genetics and Molecular Biology as well as Medicine. Their research encompasses a range of subfields including Molecular Biology, Oncology, Hematology, Cell Biology, and Cancer Research.

The main areas of scientific inquiry for Mikihiko Naito include Protein Degradation and Inhibitors, Ubiquitin and proteasome pathways, Peptidase Inhibition and Analysis, Multiple Myeloma Research and Treatments, CAR-T cell therapy research, Histone Deacetylase Inhibitors Research, and Advanced biosensing and bioanalysis techniques.

Some of the notable recent papers authored or co-authored include:

  • Critical role of mitochondrial ubiquitination and the OPTN-ATG9A axis in mitophagy, 2020, The Journal of Cell Biology
  • TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains, 2021, Molecular Cell
  • Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells, 2020, Oncogene
  • Targeting CRABP-II overcomes pancreatic cancer drug resistance by reversing lipid raft cholesterol accumulation and AKT survival signaling, 2022, Journal of Experimental & Clinical Cancer Research
  • cIAP1-based degraders induce degradation via branched ubiquitin architectures, 2022, Nature Chemical Biology

Frequent co-authors collaborating with Mikihiko Naito include:

  • Yosuke Demizu
  • Nobumichi Ohoka
  • Hidetomo Yokoo
  • Genichiro Tsuji
  • Takao Inoué

The scientist's work has been published repeatedly in venues such as:

  • ACS Medicinal Chemistry Letters
  • Bioorganic & Medicinal Chemistry
  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • Pharmaceuticals
  • The Journal of Biochemistry

Best Publications

  • Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal.

    Takashi Tsuruo;Mikihiko Naito;Akihiro Tomida;Naoya Fujita

  • Functional involvement of P-glycoprotein in blood-brain barrier

    T Tatsuta;M Naito;T Oh-hara;I Sugawara

  • Protein knockdown using methyl bestatin-ligand hybrid molecules: design and synthesis of inducers of ubiquitination-mediated degradation of cellular retinoic acid-binding proteins.

    Yukihiro Itoh;Minoru Ishikawa;Mikihiko Naito;Yuichi Hashimoto

  • Brain pericytes contribute to the induction and up-regulation of blood–brain barrier functions through transforming growth factor-β production

    Shinya Dohgu;Fuyuko Takata;Atsushi Yamauchi;Shinsuke Nakagawa

  • The 4F2hc/LAT1 complex transports L-DOPA across the blood-brain barrier.

    Takashi Kageyama;Masaru Nakamura;Akinori Matsuo;Yasuomi Yamasaki

  • Actin cleavage by CPP-32/apopain during the development of apoptosis

    Tetsuo Mashima;Mikihiko Naito;Kohji Noguchi;Douglas K. Miller

  • Brain Capillary Endothelial Cells Express two forms of Erythropoietin Receptor mRNA

    Ryoichi Yamaji;Tadayuki Okada;Maki Moriya;Mikihiko Naito

  • Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function

    Yanyan Hao;Keiko Sekine;Atsushi Kawabata;Hitoshi Nakamura;Hitoshi Nakamura

  • Identification of actin as a substrate of ICE and an ICE-like protease and involvement of an ICE-like protease but not ICE in VP-16-induced U937 apoptosis.

    Tetsuo Mashima;Mikihiko Naito;Naoya Fujita;Kohji Noguchi

  • In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs).

    Nobumichi Ohoka;Keiichiro Okuhira;Masahiro Ito;Katsunori Nagai

  • APOXIN I, A NOVEL APOPTOSIS-INDUCING FACTOR WITH L-AMINO ACID OXIDASE ACTIVITY PURIFIED FROM WESTERN DIAMONDBACK RATTLESNAKE VENOM

    Shinichi Torii;Shinichi Torii;Mikihiko Naito;Takashi Tsuruo;Takashi Tsuruo

  • ASK1 mediates apoptotic cell death induced by genotoxic stress

    Zhihong Chen;Hiroyuki Seimiya;Mikihiko Naito;Tetsuo Mashima

  • Effect of bioflavonoids on vincristine transport across blood-brain barrier.

    Yoshiharu Mitsunaga;Hitomi Takanaga;Hirotami Matsuo;Mikihiko Naito

  • Aspartate-Based Inhibitor of Interleukin-1β-Converting Enzyme Prevents Antitumor Agent-Induced Apoptosis in Human Myeloid Leukemia U937 Cells

    T. Mashima;M. Naito;S. Kataoka;H. Kawai

  • Small Molecules Destabilize cIAP1 by Activating Auto-ubiquitylation

    Keiko Sekine;Kohei Takubo;Ryo Kikuchi;Michie Nishimoto

  • Selective induction of apoptosis in Philadelphia chromosome-positive chronic myelogenous leukemia cells by an inhibitor of BCR–ABL tyrosine kinase, CGP 57148

    Shingo Dan;Mikihiko Naito;Takashi Tsuruo;Takashi Tsuruo

  • Design, synthesis and biological evaluation of nuclear receptor-degradation inducers.

    Yukihiro Itoh;Risa Kitaguchi;Minoru Ishikawa;Mikihiko Naito

  • Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands

    Norihito Shibata;Katsunori Nagai;Yoko Morita;Osamu Ujikawa

  • Comparative Study on Reversal Efficacy of SDZ PSC 833, Cyclosporin a and Verapamil on Multidrug Resistance in vitro and in vivo

    Toru Watanabe;Harumi Tsuge;Tomoko Oh-Hara;Mikihiko Naito

  • Phosphatidylserine Externalization Is a Downstream Event of Interleukin-1β–Converting Enzyme Family Protease Activation During Apoptosis

    Mikihiko Naito;Mikihiko Naito;Kimie Nagashima;Kimie Nagashima;Tetsuo Mashima;Tetsuo Mashima;Takashi Tsuruo;Takashi Tsuruo

Frequent Co-Authors

Takashi Tsuruo
Takashi Tsuruo Japanese Foundation For Cancer Research
Takashi Tsuruo
Takashi Tsuruo Japanese Foundation For Cancer Research
Naoya Fujita
Naoya Fujita Japanese Foundation For Cancer Research
Yuichi Hashimoto
Yuichi Hashimoto University of Tokyo
Ichiro Kudo
Ichiro Kudo Showa University
Keizo Inoue
Keizo Inoue University of Tokyo
Yuichi Sugiyama
Yuichi Sugiyama University of Tokyo
Hiroshi Suzuki
Hiroshi Suzuki Obihiro University of Agriculture and Veterinary Medicine
John C. Reed
John C. Reed Johnson & Johnson (United States)
Yoshiro Saito
Yoshiro Saito Tohoku University

External Links

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Best Scientists Citing Mikihiko Naito

Takashi Tsuruo

Takashi Tsuruo

Japanese Foundation For Cancer Research

Publications: 86

Tetsuya Terasaki

Tetsuya Terasaki

Tohoku University

Publications: 44

Takashi Tsuruo

Takashi Tsuruo

Japanese Foundation For Cancer Research

Publications: 35

Naoya Fujita

Naoya Fujita

Japanese Foundation For Cancer Research

Publications: 33

Craig M. Crews

Craig M. Crews

Yale University

Publications: 33

Sumio Ohtsuki

Sumio Ohtsuki

Kumamoto University

Publications: 28

Yuichi Sugiyama

Yuichi Sugiyama

University of Tokyo

Publications: 28

Ken-ichi Hosoya

Ken-ichi Hosoya

University of Toyama

Publications: 25

Hiroshi Suzuki

Hiroshi Suzuki

Obihiro University of Agriculture and Veterinary Medicine

Publications: 16

Makoto Murakami

Makoto Murakami

University of Tokyo

Publications: 16

Tsonwin Hai

Tsonwin Hai

The Ohio State University

Publications: 15

Hideyuki Shigemori

Hideyuki Shigemori

University of Tsukuba

Publications: 15

William A. Banks

William A. Banks

University of Washington

Publications: 15

Ichiro Kudo

Ichiro Kudo

Showa University

Publications: 15

Roméo Cecchelli

Roméo Cecchelli

Artois University

Publications: 15

Masanori Tachikawa

Masanori Tachikawa

University of Tokushima

Publications: 14

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