World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
20440
World Ranking
10014
National Ranking
4384

Research.com Recognitions

  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Tsonwin Hai is affiliated with The Ohio State University in the United States. Their research focuses primarily on immunology and microbiology, with an emphasis on immunotherapy, immune cell function, and cancer-related immune responses. Hai's scholarly work engages several interconnected fields including immunology, nutrition and dietetics, molecular biology, and oncology.

The scientist's recent published papers include:

  • Tumor factors stimulate lysosomal degradation of tumor antigens and undermine their cross-presentation in lung cancer, 2022, Nature Communications
  • Retraction: Loss of Metallothionein Predisposes Mice to Diethylnitrosamine-Induced Hepatocarcinogenesis by Activating NF-κB Target Genes, 2023, Cancer Research

The research topics Hai has contributed to include:

  • Immunotherapy and Immune Responses
  • Immune Cell Function and Interaction
  • Immune cells in cancer
  • Trace Elements in Health
  • Mitochondrial Function and Pathology
  • Drug Transport and Resistance Mechanisms

Frequent co-authors working alongside Hai are:

  • Zhen Lu
  • Jinyun Chen
  • Pengfei Yu
  • Matthew J. Atherton
  • Jun Gui

Hai's studies have appeared mainly in:

  • Nature Communications
  • Cancer Research

In 2008, Hai was recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.

    Tsonwin Hai;Tom Curran

  • Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.

    T W Hai;F Liu;W J Coukos;M R Green

  • The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis

    Tsonwin Hai;Matthew G Hartman

  • Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4

    Mark Gilchrist;Vesteinn Thorsson;Bin Li;Alistair G. Rust

  • ATF3 and stress responses.

    Tsonwin Hai;Curt D. Wolfgang;Derek K. Marsee;Amy E. Allen

  • Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.

    Daniel A. Cunha;Paul Hekerman;Laurence Ladrière;Angie Bazarra-Castro

  • Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response.

    Timothy W. Fawcett;Jennifer L. Martindale;Kathryn Z. Guyton;Tsonwin Hai

  • Transcription Factor ATF Interacts with the TATA Factor to Facilitate Establishment of a Preinitiation Complex

    Masami Horikoshi;Tsonwin Hai;Young-Sun Lin;Michael R. Green

  • Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response.

    Hao Yuan Jiang;Sheree A. Wek;Barbara C. McGrath;Dan Lu

  • Electrophilic properties of itaconate and derivatives regulate the IκBζ–ATF3 inflammatory axis

    Monika Bambouskova;Laurent Gorvel;Vicky Lampropoulou;Alexey Sergushichev

  • Tissue-specific Pattern of Stress Kinase Activation in Ischemic/Reperfused Heart and Kidney

    Tinggui Yin;Gulzar Sandhu;Curt D. Wolfgang;Althea Burrier

  • Dimerization specificity of the leucine zipper-containing bZIP motif on DNA binding: prediction and rational design.

    C. R. Vinson;Tsonwin Hai;S. M. Boyd

  • Analysis of ATF3, a transcription factor induced by physiological stresses and modulated by gadd153/Chop10.

    Benjamin P C Chen;Curt D. Wolfgang;Tsonwin Hai

  • ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells.

    Qiuyan Wang;Helena Mora-Jensen;Marc A. Weniger;Patricia Perez-Galan

  • Role for Activating Transcription Factor 3 in Stress-Induced β-Cell Apoptosis

    Matthew G. Hartman;Dan Lu;Mi Lyang Kim;Gary J. Kociba

  • ATF3, a hub of the cellular adaptive-response network, in the pathogenesis of diseases: is modulation of inflammation a unifying component?

    Tsonwin Hai;Christopher C. Wolford;Yi-Seok Chang

  • ATF4 degradation relies on a phosphorylation-dependent interaction with the SCF(betaTrCP) ubiquitin ligase.

    Irina Lassot;Emmanuel Ségéral;Clarisse Berlioz-Torrent;Herve Durand

  • ATF3 and ATF3 delta Zip. Transcriptional repression versus activation by alternatively spliced isoforms.

    Benjamin P C Chen;Guosheng Liang;James Whelan;Tsonwin Hai

  • ATF3 gene. Genomic organization, promoter, and regulation.

    Guosheng Liang;Curt D. Wolfgang;Benjamin P C Chen;Tsu Hua Chen

  • A family of immunologically related transcription factors that includes multiple forms of ATF and AP-1.

    Tsonwin Hai;Fang Liu;E. A. Allegretto;M. Karin

Frequent Co-Authors

Benjamin P C Chen
Benjamin P C Chen The University of Texas Southwestern Medical Center
David Ron
David Ron University of Cambridge
Marc Montminy
Marc Montminy Salk Institute for Biological Studies
Michael R. Freeman
Michael R. Freeman Cedars-Sinai Medical Center
Shane T. Grey
Shane T. Grey Garvan Institute of Medical Research
H. Leighton Grimes
H. Leighton Grimes Cincinnati Children's Hospital Medical Center
Periannan Kuppusamy
Periannan Kuppusamy The Ohio State University
Morris F. White
Morris F. White Boston Children's Hospital
Michael C. Ostrowski
Michael C. Ostrowski Medical University of South Carolina
Akira Sawa
Akira Sawa Johns Hopkins University

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