D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 58 Citations 11,802 127 World Ranking 8863 National Ranking 3982

Research.com Recognitions

Awards & Achievements

2018 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • DNA

Her primary scientific interests are in Cell biology, Mitochondrial intermembrane space, Intermembrane space, Mitochondrial membrane transport protein and Inner mitochondrial membrane. Carla M. Koehler specializes in Cell biology, namely Translocase of the inner membrane. The concepts of her Mitochondrial intermembrane space study are interwoven with issues in Exoribonuclease, RNase P and Mitochondrial RNA processing.

Her studies examine the connections between Intermembrane space and genetics, as well as such issues in Membrane protein, with regards to Inner membrane and Translocase. Her Inner mitochondrial membrane research is included under the broader classification of Mitochondrion. Her research investigates the connection between Translocase of the outer membrane and topics such as Sorting and assembly machinery that intersect with issues in mitochondrial fusion and Mitochondrial biogenesis.

Her most cited work include:

  • Importing Mitochondrial Proteins: Machineries and Mechanisms (970 citations)
  • UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells (365 citations)
  • Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal (303 citations)

What are the main themes of her work throughout her whole career to date?

Carla M. Koehler mostly deals with Cell biology, Mitochondrion, Biochemistry, Mitochondrial intermembrane space and Translocase of the inner membrane. Her Cell biology study combines topics in areas such as Intermembrane space and Mitochondrial carrier. Carla M. Koehler focuses mostly in the field of Mitochondrial carrier, narrowing it down to matters related to ATP–ADP translocase and, in some cases, DNAJA3.

She combines subjects such as Molecular biology, Oxidative phosphorylation and Mutant with her study of Mitochondrion. Her Mitochondrial intermembrane space research integrates issues from Non-coding RNA, Biophysics, Translocase and Cysteine. Her Translocase of the inner membrane research is multidisciplinary, incorporating elements of Mitochondrial biogenesis and Inner membrane.

She most often published in these fields:

  • Cell biology (60.66%)
  • Mitochondrion (41.80%)
  • Biochemistry (34.43%)

What were the highlights of her more recent work (between 2016-2020)?

  • Cell biology (60.66%)
  • Mitochondrion (41.80%)
  • Zebrafish (5.74%)

In recent papers she was focusing on the following fields of study:

Her scientific interests lie mostly in Cell biology, Mitochondrion, Zebrafish, Membrane potential and In vivo. In her research, Endosome is intimately related to Autophagy, which falls under the overarching field of Cell biology. Mitochondrion and Polynucleotide phosphorylase are two areas of study in which she engages in interdisciplinary work.

Zebrafish is a subfield of Biochemistry that Carla M. Koehler tackles. Her Membrane potential study integrates concerns from other disciplines, such as Preclinical imaging, Cancer cell and Oxidative phosphorylation. Her In vivo research incorporates themes from Caenorhabditis elegans, Pharmacology, Drug and Mechanism of action.

Between 2016 and 2020, her most popular works were:

  • In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer (55 citations)
  • Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria (46 citations)
  • Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS) (43 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Carla M. Koehler mostly deals with Mitochondrion, Cell biology, In vivo, Preclinical imaging and SOD1. Her study in Mitochondrion is interdisciplinary in nature, drawing from both Mitochondrial intermembrane space, Electron transport chain, Oxidoreductase and Actin. Her research in Cell biology intersects with topics in Calcium metabolism and Calcium.

The various areas that she examines in her In vivo study include Caenorhabditis elegans, Cryptococcus neoformans and Mechanism of action. The Preclinical imaging study combines topics in areas such as Cancer cell, Cancer, Cell growth, Oxidative phosphorylation and Membrane potential. Her SOD1 research incorporates elements of Zebrafish, Danio and Cytotoxicity.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Importing Mitochondrial Proteins: Machineries and Mechanisms

Agnieszka Chacinska;Carla M Koehler;Dusanka Milenkovic;Trevor James Lithgow.
Cell (2009)

1269 Citations

UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells

Jin Zhang;Ivan Khvorostov;Jason S. Hong;Yavuz Oktay.
The EMBO Journal (2011)

493 Citations

Human deafness dystonia syndrome is a mitochondrial disease

Carla M. Koehler;Danielle Leuenberger;Sabeeha Merchant;Anja Renold.
Proceedings of the National Academy of Sciences of the United States of America (1999)

440 Citations

NEW DEVELOPMENTS IN MITOCHONDRIAL ASSEMBLY

Carla M. Koehler.
Annual Review of Cell and Developmental Biology (2004)

422 Citations

Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal

Jin Zhang;Esther Nuebel;George Q. Daley;Carla M. Koehler.
Cell Stem Cell (2012)

392 Citations

Import of Mitochondrial Carriers Mediated by Essential Proteins of the Intermembrane Space

Carla M. Koehler;Ernst Jarosch;Ernst Jarosch;Kostas Tokatlidis;Kostas Tokatlidis;Karl Schmid;Karl Schmid.
Science (1998)

350 Citations

Cardiolipin defines the interactome of the major ADP/ATP carrier protein of the mitochondrial inner membrane

Steven M. Claypool;Yavuz Oktay;Pinmanee Boontheung;Joseph A. Loo.
Journal of Cell Biology (2008)

337 Citations

PNPASE Regulates RNA Import into Mitochondria

Geng Wang;Hsiao-Wen Chen;Yavuz Oktay;Jin Zhang.
Cell (2010)

337 Citations

The complexity of cardiolipin in health and disease

Steven M. Claypool;Carla M. Koehler.
Trends in Biochemical Sciences (2012)

300 Citations

Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria.

Estela Area-Gomez;Ad J.C. de Groof;Istvan Boldogh;Thomas D. Bird.
American Journal of Pathology (2009)

291 Citations

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