His main research concerns Cell biology, Lung injury, Immunology, Chemotaxis and Pathology. His research integrates issues of Innate immune system and Actin cytoskeleton, Cytoskeleton in his study of Cell biology. Gregory P. Downey combines subjects such as Respiratory disease, Pathogenesis, Sepsis, ARDS and Proteolytic enzymes with his study of Lung injury.
His Immunology study combines topics from a wide range of disciplines, such as Stimulation and Lung. In his study, Biochemistry and Lagomorpha is inextricably linked to Biophysics, which falls within the broad field of Lung. His studies deal with areas such as Molecular biology, Motility and Actin as well as Chemotaxis.
The scientist’s investigation covers issues in Cell biology, Immunology, Lung injury, Signal transduction and Lung. His work focuses on many connections between Cell biology and other disciplines, such as Biochemistry, that overlap with his field of interest in Biophysics. His research on Immunology frequently links to adjacent areas such as Respiratory disease.
The study incorporates disciplines such as Elastase, ARDS and Apoptosis in addition to Lung injury. His Signal transduction study deals with Cancer research intersecting with Transforming growth factor. His Lung research is multidisciplinary, relying on both Disease and Pathology.
His scientific interests lie mostly in Lung injury, Cell biology, Pathology, Lung and Signal transduction. Gregory P. Downey has researched Lung injury in several fields, including Bronchoalveolar lavage and Pulmonary medicine. His Cell biology research focuses on subjects like Cell adhesion, which are linked to Cell adhesion molecule.
His research in Pathology intersects with topics in Tumor necrosis factor alpha, Cell culture and Matrix metalloproteinase. His work carried out in the field of Lung brings together such families of science as Proteases, Receptor and Immunology. His Signal transduction research incorporates elements of Chemokine, Interleukin 8, Cytokine and Immunoprecipitation.
His primary areas of study are Immunology, Lung, Lung injury, Signal transduction and Pathology. His Immunology research incorporates themes from Respiratory tract infections and Pneumonia. Gregory P. Downey interconnects Inflammation, Receptor, Bronchoalveolar lavage and Cell adhesion in the investigation of issues within Lung injury.
His studies examine the connections between Signal transduction and genetics, as well as such issues in Cancer research, with regards to Downregulation and upregulation, Neutrophil elastase and Chemokine. His Pathology research includes elements of Cell culture, Genetically modified mouse, Transgene and Prostate. His study with Focal adhesion involves better knowledge in Cell biology.
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An Official American Thoracic Society Workshop Report: Features and Measurements of Experimental Acute Lung Injury in Animals
Gustavo Matute-Bello;Gregory Downey;Bethany B. Moore;Steve D. Groshong.
American Journal of Respiratory Cell and Molecular Biology (2011)
Efficacy and safety of sirolimus in lymphangioleiomyomatosis.
Francis X. McCormack;Yoshikazu Inoue;Joel Moss;Lianne G. Singer.
The New England Journal of Medicine (2011)
Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function
Lea Fialkow;Yingchun Wang;Gregory P. Downey.
Free Radical Biology and Medicine (2007)
Mechanics of stimulated neutrophils: cell stiffening induces retention in capillaries
GS Worthen;B Schwab;EL Elson;GP Downey.
Neutrophil activation and acute lung injury.
Warren L. Lee;Gregory P. Downey.
Current Opinion in Critical Care (2001)
Leukocyte elastase: physiological functions and role in acute lung injury.
Warren L. Lee;Gregory P. Downey.
American Journal of Respiratory and Critical Care Medicine (2001)
The remote ischemic preconditioning stimulus modifies inflammatory gene expression in humans
Igor E. Konstantinov;Sara Arab;Rajesh K. Kharbanda;Jia Li.
Physiological Genomics (2004)
Transepithelial migration of neutrophils: mechanisms and implications for acute lung injury.
Rachel L. Zemans;Sean P. Colgan;Gregory P. Downey;Gregory P. Downey.
American Journal of Respiratory Cell and Molecular Biology (2009)
Oxidative stress and acute lung injury.
Chung-Wai Chow;Maria Teresa Herrera Abreu;Tomoko Suzuki;Gregory P. Downey.
American Journal of Respiratory Cell and Molecular Biology (2003)
Rac1 Deletion in Mouse Neutrophils Has Selective Effects on Neutrophil Functions
Michael Glogauer;Christophe C. Marchal;Fei Zhu;Aelaf Worku.
Journal of Immunology (2003)
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