D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 82 Citations 21,355 248 World Ranking 2358 National Ranking 1279

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Enzyme

His main research concerns Cell biology, Lung injury, Immunology, Chemotaxis and Pathology. His research integrates issues of Innate immune system and Actin cytoskeleton, Cytoskeleton in his study of Cell biology. Gregory P. Downey combines subjects such as Respiratory disease, Pathogenesis, Sepsis, ARDS and Proteolytic enzymes with his study of Lung injury.

His Immunology study combines topics from a wide range of disciplines, such as Stimulation and Lung. In his study, Biochemistry and Lagomorpha is inextricably linked to Biophysics, which falls within the broad field of Lung. His studies deal with areas such as Molecular biology, Motility and Actin as well as Chemotaxis.

His most cited work include:

  • An Official American Thoracic Society Workshop Report: Features and Measurements of Experimental Acute Lung Injury in Animals (766 citations)
  • Efficacy and safety of sirolimus in lymphangioleiomyomatosis. (667 citations)
  • Efficacy and safety of sirolimus in lymphangioleiomyomatosis. (667 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Cell biology, Immunology, Lung injury, Signal transduction and Lung. His work focuses on many connections between Cell biology and other disciplines, such as Biochemistry, that overlap with his field of interest in Biophysics. His research on Immunology frequently links to adjacent areas such as Respiratory disease.

The study incorporates disciplines such as Elastase, ARDS and Apoptosis in addition to Lung injury. His Signal transduction study deals with Cancer research intersecting with Transforming growth factor. His Lung research is multidisciplinary, relying on both Disease and Pathology.

He most often published in these fields:

  • Cell biology (43.07%)
  • Immunology (22.63%)
  • Lung injury (16.79%)

What were the highlights of his more recent work (between 2011-2021)?

  • Lung injury (16.79%)
  • Cell biology (43.07%)
  • Pathology (13.50%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Lung injury, Cell biology, Pathology, Lung and Signal transduction. Gregory P. Downey has researched Lung injury in several fields, including Bronchoalveolar lavage and Pulmonary medicine. His Cell biology research focuses on subjects like Cell adhesion, which are linked to Cell adhesion molecule.

His research in Pathology intersects with topics in Tumor necrosis factor alpha, Cell culture and Matrix metalloproteinase. His work carried out in the field of Lung brings together such families of science as Proteases, Receptor and Immunology. His Signal transduction research incorporates elements of Chemokine, Interleukin 8, Cytokine and Immunoprecipitation.

Between 2011 and 2021, his most popular works were:

  • The fibroproliferative response in acute respiratory distress syndrome: mechanisms and clinical significance (128 citations)
  • Official American Thoracic Society/Japanese Respiratory Society Clinical Practice Guidelines: Lymphangioleiomyomatosis Diagnosis and Management (118 citations)
  • Serum VEGF-D concentration as a biomarker of lymphangioleiomyomatosis severity and treatment response: a prospective analysis of the Multicenter International Lymphangioleiomyomatosis Efficacy of Sirolimus (MILES) trial (117 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Enzyme

His primary areas of study are Immunology, Lung, Lung injury, Signal transduction and Pathology. His Immunology research incorporates themes from Respiratory tract infections and Pneumonia. Gregory P. Downey interconnects Inflammation, Receptor, Bronchoalveolar lavage and Cell adhesion in the investigation of issues within Lung injury.

His studies examine the connections between Signal transduction and genetics, as well as such issues in Cancer research, with regards to Downregulation and upregulation, Neutrophil elastase and Chemokine. His Pathology research includes elements of Cell culture, Genetically modified mouse, Transgene and Prostate. His study with Focal adhesion involves better knowledge in Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

An Official American Thoracic Society Workshop Report: Features and Measurements of Experimental Acute Lung Injury in Animals

Gustavo Matute-Bello;Gregory Downey;Bethany B. Moore;Steve D. Groshong.
American Journal of Respiratory Cell and Molecular Biology (2011)

1184 Citations

Efficacy and safety of sirolimus in lymphangioleiomyomatosis.

Francis X. McCormack;Yoshikazu Inoue;Joel Moss;Lianne G. Singer.
The New England Journal of Medicine (2011)

1021 Citations

Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function

Lea Fialkow;Yingchun Wang;Gregory P. Downey.
Free Radical Biology and Medicine (2007)

795 Citations

Mechanics of stimulated neutrophils: cell stiffening induces retention in capillaries

GS Worthen;B Schwab;EL Elson;GP Downey.
Science (1989)

688 Citations

Neutrophil activation and acute lung injury.

Warren L. Lee;Gregory P. Downey.
Current Opinion in Critical Care (2001)

535 Citations

Leukocyte elastase: physiological functions and role in acute lung injury.

Warren L. Lee;Gregory P. Downey.
American Journal of Respiratory and Critical Care Medicine (2001)

427 Citations

The remote ischemic preconditioning stimulus modifies inflammatory gene expression in humans

Igor E. Konstantinov;Sara Arab;Rajesh K. Kharbanda;Jia Li.
Physiological Genomics (2004)

405 Citations

Transepithelial migration of neutrophils: mechanisms and implications for acute lung injury.

Rachel L. Zemans;Sean P. Colgan;Gregory P. Downey;Gregory P. Downey.
American Journal of Respiratory Cell and Molecular Biology (2009)

373 Citations

Oxidative stress and acute lung injury.

Chung-Wai Chow;Maria Teresa Herrera Abreu;Tomoko Suzuki;Gregory P. Downey.
American Journal of Respiratory Cell and Molecular Biology (2003)

362 Citations

Rac1 Deletion in Mouse Neutrophils Has Selective Effects on Neutrophil Functions

Michael Glogauer;Christophe C. Marchal;Fei Zhu;Aelaf Worku.
Journal of Immunology (2003)

335 Citations

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