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Immunology

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81
Citations
23247
World Ranking
1571
National Ranking
785

Medicine

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82
Citations
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World Ranking
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National Ranking
8123

Overview

Christopher C. Silliman is affiliated with the University of Colorado Denver in the United States. Their research focuses primarily on medicine, with extensive work in critical care and intensive care medicine, emergency medicine, epidemiology, biochemistry, and neurology.

The scientist's published work covers several main topics including trauma, hemostasis, coagulopathy, and resuscitation; trauma and emergency care studies; sepsis diagnosis and treatment; blood transfusion and management; traumatic brain injury and neurovascular disturbances; cardiac arrest and resuscitation; and venous thromboembolism diagnosis and management.

Christopher C. Silliman has contributed to numerous publications in a variety of venues, frequently appearing in:

  • The Journal of Trauma: Injury, Infection, and Critical Care (17 publications)
  • Shock (6 publications)
  • Journal of the American College of Surgeons (5 publications)
  • Annals of Surgery (3 publications)
  • Transfusion (3 publications)

Recent papers authored or co-authored by Christopher C. Silliman include:

  • "Succinate Activation of SUCNR1 Predisposes Severely Injured Patients to Neutrophil-mediated ARDS," 2020, Annals of Surgery
  • "Estradiol provokes hypercoagulability and affects fibrin biology: A mechanistic exploration of sex dimorphisms in coagulation," 2022, The Journal of Trauma: Injury, Infection, and Critical Care
  • "Whole Blood Thrombin Generation in Severely Injured Patients Requiring Massive Transfusion," 2021, Journal of the American College of Surgeons
  • "Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength," 2022, Platelets
  • "Hormones, age, and sex affect platelet responsiveness in vitro," 2022, Transfusion

Christopher C. Silliman frequently collaborates with colleagues including Ernest E. Moore, Mitchell J. Cohen, Angelo D'Alessandro, Kirk C. Hansen, and Angela Sauaia, with the highest number of collaborations being with Ernest E. Moore (47 joint works).

Best Publications

  • Transfusion-related acute lung injury : Definition and review

    Pearl Toy;Mark A. Popovsky;Edward Abraham;Daniel R. Ambruso

  • Transfusion-related acute lung injury: epidemiology and a prospective analysis of etiologic factors

    Christopher C. Silliman;Lynn K. Boshkov;Zahra Mehdizadehkashi;David J. Elzi

  • Age of transfused blood is an independent risk factor for postinjury multiple organ failure

    Garret Zallen;Patrick J Offner;Ernest E Moore;John Blackwell

  • Goal-directed Hemostatic Resuscitation of Trauma-induced Coagulopathy: A Pragmatic Randomized Clinical Trial Comparing a Viscoelastic Assay to Conventional Coagulation Assays.

    Eduardo Gonzalez;Ernest E. Moore;Hunter B. Moore;Michael P. Chapman

  • The association of biologically active lipids with the development of transfusion‐related acute lung injury: a retrospective study

    Christopher C. Silliman;Andrew J. Paterson;William O. Dickey;David F. Stroncek

  • Plasma and lipids from stored packed red blood cells cause acute lung injury in an animal model.

    C C Silliman;N F Voelkel;J D Allard;D J Elzi

  • Transfusion-related acute lung injury

    Christopher C. Silliman;Christopher C. Silliman;Daniel R. Ambruso;Daniel R. Ambruso;Lynn K. Boshkov;Lynn K. Boshkov

  • Soluble CD40 ligand accumulates in stored blood components, primes neutrophils through CD40, and is a potential cofactor in the development of transfusion-related acute lung injury.

    Samina Yasmin Khan;Marguerite R. Kelher;Joanna M. Heal;Neil Blumberg

  • Structural organization of the neutrophil NADPH oxidase: phosphorylation and translocation during priming and activation

    Forest R. Sheppard;Forest R. Sheppard;Marguerite R. Kelher;Marguerite R. Kelher;Ernest E. Moore;Ernest E. Moore;Nathan J. D. McLaughlin;Nathan J. D. McLaughlin

  • Hyperfibrinolysis, physiologic fibrinolysis, and fibrinolysis shutdown: the spectrum of postinjury fibrinolysis and relevance to antifibrinolytic therapy.

    Hunter B. Moore;Ernest E. Moore;Eduardo Gonzalez;Michael P. Chapman

  • Increased Rate of Infection Associated With Transfusion of Old Blood After Severe Injury

    Patrick J. Offner;Ernest E. Moore;Walter L. Biffl;Jeffrey L. Johnson

  • Partial characterization of lipids that develop during the routine storage of blood and prime the neutrophil NADPH oxidase.

    Christopher C. Silliman;Keith L. Clay;Gail W. Thurman;Chris A. Johnson

  • Plasma-first resuscitation to treat haemorrhagic shock during emergency ground transportation in an urban area: a randomised trial.

    Hunter B Moore;Ernest E Moore;Ernest E Moore;Michael P Chapman;Kevin McVaney

  • Early platelet dysfunction: an unrecognized role in the acute coagulopathy of trauma.

    Max V. Wohlauer;Ernest E. Moore;Ernest E. Moore;Scott Thomas;Scott Thomas;Angela Sauaia

  • Plasma and lipids from stored platelets cause acute lung injury in an animal model.

    Christopher C. Silliman;A. Jason Bjornsen;Travis H. Wyman;Marguerite Kelher

  • In vitro release of vascular endothelial growth factor during platelet aggregation

    James P. Maloney;Christopher C. Silliman;Daniel R. Ambruso;Jun Wang

  • The two-event model of transfusion-related acute lung injury.

    Christopher C. Silliman

  • Fibrinolysis greater than 3% is the critical value for initiation of antifibrinolytic therapy.

    Michael P. Chapman;Ernest E. Moore;Christopher R. Ramos;Arsen Ghasabyan

  • HMGB1 is markedly elevated within 6 hours of mechanical trauma in humans.

    Erik D. Peltz;Ernest E. Moore;Phillip C. Eckels;Sagar S. Damle

  • Identification of lipids that accumulate during the routine storage of prestorage leukoreduced red blood cells and cause acute lung injury

    Christopher C. Silliman;Ernest E. Moore;Marguerite R. Kelher;Samina Y. Khan

Frequent Co-Authors

Ernest E. Moore
Ernest E. Moore University of Colorado Denver
Anirban Banerjee
Anirban Banerjee University of Colorado Anschutz Medical Campus
Jeffrey L. Johnson
Jeffrey L. Johnson LAC+USC Medical Center
Kirk C. Hansen
Kirk C. Hansen University of Colorado Anschutz Medical Campus
Angelo D'Alessandro
Angelo D'Alessandro University of Colorado Denver
Walter L. Biffl
Walter L. Biffl University of California, Irvine
Mitchell J. Cohen
Mitchell J. Cohen University of Colorado Denver
Travis Nemkov
Travis Nemkov University of Colorado Denver
Kenneth L. Jones
Kenneth L. Jones University of California, San Diego
Martin D. McCarter
Martin D. McCarter University of Colorado Anschutz Medical Campus

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