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Biology and Biochemistry

D-Index
94
Citations
31229
World Ranking
2021
National Ranking
1102

Overview

Angelo D'Alessandro is affiliated with the University of Colorado Denver in the United States, conducting research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Molecular Biology, Physiology, Hematology, Genetics, and Immunology.

The main topics of D'Alessandro's research focus on areas such as:

  • Erythrocyte Function and Pathophysiology
  • Hemoglobinopathies and Related Disorders
  • Neonatal Health and Biochemistry
  • Metabolomics and Mass Spectrometry Studies
  • Acute Myeloid Leukemia Research
  • Cancer, Hypoxia, and Metabolism
  • Epigenetics and DNA Methylation

D'Alessandro has contributed to numerous publications, with frequent appearances in journals such as:

  • Blood
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Transfusion
  • Frontiers in Physiology
  • Haematologica

Some notable recent papers include:

  • COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status, 2020, JCI Insight
  • Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia, 2020, Cancer Discovery
  • Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients, 2020, Journal of Proteome Research
  • MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling, 2020, Genes & Development
  • Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells, 2020, Nature Cancer

Frequent collaborators in D'Alessandro's research include:

  • Julie A. Reisz
  • Travis Nemkov
  • Monika Dzieciątkowska
  • Kirk C. Hansen
  • James C. Zimring

Best Publications

  • Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia.

    Daniel A. Pollyea;Brett M. Stevens;Courtney L. Jones;Amanda Winters

  • Report of a National Conference on Donation after Cardiac Death

    J. L. Bernat;A. M. D'Alessandro;F. K. Port;Thomas P Bleck

  • COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status.

    Tiffany Thomas;Davide Stefanoni;Julie A. Reisz;Travis Nemkov

  • Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells.

    Courtney L. Jones;Brett M. Stevens;Angelo D'Alessandro;Julie A. Reisz

  • OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.

    Carlo Marchetti;Benjamin Swartzwelter;Fabia Gamboni;Charles P. Neff

  • ASTS recommended practice guidelines for controlled donation after cardiac death organ procurement and transplantation.

    D. J. Reich;D. C. Mulligan;P. L. Abt;T. L. Pruett

  • Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia.

    Shanshan Pei;Daniel A. Pollyea;Annika Gustafson;Brett M. Stevens

  • An update on red blood cell storage lesions, as gleaned through biochemistry and omics technologies.

    Angelo D'Alessandro;Anastasios G. Kriebardis;Sara Rinalducci;Marianna H. Antonelou

  • p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression

    Sung-Hwan Moon;Chun-Hao Huang;Chun-Hao Huang;Chun-Hao Huang;Shauna L. Houlihan;Kausik Regunath

  • Red blood cell storage lesion: causes and potential clinical consequences.

    Tatsuro Yoshida;Michel Prudent;Angelo D’Alessandro

  • The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD.

    Taylor K. Soderborg;Sarah E. Clark;Christopher E. Mulligan;Rachel C. Janssen

  • Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients.

    Tiffany Thomas;Davide Stefanoni;Monika Dzieciatkowska;Aaron Issaian

  • The TP53 Apoptotic Network Is a Primary Mediator of Resistance to BCL2 Inhibition in AML Cells

    Tamilla Nechiporuk;Stephen E. Kurtz;Olga Nikolova;Tingting Liu

  • Time-course investigation of SAGM-stored leukocyte-filtered red bood cell concentrates: from metabolism to proteomics.

    Angelo D’Alessandro;Gian Maria D’Amici;Stefania Vaglio;Lello Zolla

  • A TDO2-AhR signaling axis facilitates anoikis resistance and metastasis in triple-negative breast cancer.

    Nicholas C. D'Amato;Thomas J. Rogers;Michael A. Gordon;Lisa I. Greene

  • Red blood cell storage: the story so far.

    Angelo D'Alessandro;Giancarlo Liumbruno;Giuliano Grazzini;Lello Zolla

  • Identification of MicroRNA-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 (Polypyrimidine Tract Binding Protein) and Pyruvate Kinase M2.

    Paola Caruso;Benjamin John Dunmore;Kenny Schlosser;Sandra Schoors

  • TNF-α–driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging

    Pavel Davizon-Castillo;Brandon McMahon;Sonia Aguila;David Bark

  • A three-minute method for high-throughput quantitative metabolomics and quantitative tracing experiments of central carbon and nitrogen pathways

    Travis Nemkov;Kirk C. Hansen;Angelo D'Alessandro

  • High-Throughput Metabolomics: Isocratic and Gradient Mass Spectrometry-Based Methods.

    Travis Nemkov;Julie A. Reisz;Sarah Gehrke;Kirk C. Hansen

Frequent Co-Authors

Travis Nemkov
Travis Nemkov University of Colorado Denver
Kirk C. Hansen
Kirk C. Hansen University of Colorado Anschutz Medical Campus
Hans W. Sollinger
Hans W. Sollinger University of Wisconsin–Madison
Stuart J. Knechtle
Stuart J. Knechtle Duke University
Lello Zolla
Lello Zolla Tuscia University
Ernest E. Moore
Ernest E. Moore University of Colorado Denver
Christopher C. Silliman
Christopher C. Silliman University of Colorado Denver
Yang Xia
Yang Xia The University of Texas Health Science Center at Houston
John D. Pirsch
John D. Pirsch University of Wisconsin–Madison
Anirban Banerjee
Anirban Banerjee University of Colorado Anschutz Medical Campus

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