What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Cell membrane
His main research concerns Biochemistry, Amyloid precursor protein, APH-1, Presenilin and Cell biology.
Gopal Thinakaran focuses mostly in the field of Biochemistry, narrowing it down to topics relating to Alpha secretase and, in certain cases, Senile plaques.
As a member of one scientific family, Gopal Thinakaran mostly works in the field of Amyloid precursor protein, focusing on Amyloid and, on occasion, Alzheimer's disease, Neuroscience and Endocrinology.
Gopal Thinakaran has researched APH-1 in several fields, including PEN-2, Gamma-secretase complex and Nicastrin.
The concepts of his Presenilin study are interwoven with issues in Molecular biology, Gene and Proteolysis.
Gopal Thinakaran has included themes like Secretion and Cleavage in his Cell biology study.
His most cited work include:
- Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo (1356 citations)
- ENDOPROTEOLYSIS OF PRESENILIN 1 AND ACCUMULATION OF PROCESSED DERIVATIVES IN VIVO (950 citations)
- Amyloid Precursor Protein Trafficking, Processing, and Function (821 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Amyloid precursor protein, Cell biology, Presenilin, Biochemistry and Neuroscience.
His work deals with themes such as Senile plaques and Amyloid, which intersect with Amyloid precursor protein.
His study focuses on the intersection of Cell biology and fields such as Transmembrane protein with connections in the field of Ectodomain.
Gopal Thinakaran combines subjects such as Molecular biology, Gene and Membrane protein with his study of Presenilin.
Gopal Thinakaran interconnects Dementia and Neurodegeneration in the investigation of issues within Neuroscience.
His APH-1 research integrates issues from PEN-2 and Gamma-secretase complex.
He most often published in these fields:
- Amyloid precursor protein (47.71%)
- Cell biology (44.44%)
- Presenilin (36.60%)
What were the highlights of his more recent work (between 2014-2020)?
- Cell biology (44.44%)
- Amyloid precursor protein (47.71%)
- Neuroscience (20.92%)
In recent papers he was focusing on the following fields of study:
Gopal Thinakaran spends much of his time researching Cell biology, Amyloid precursor protein, Neuroscience, Amyloid and Receptor.
His studies deal with areas such as Presenilin and Senile plaques as well as Cell biology.
His Presenilin research includes elements of Transgene, Mutation, Protease, Exon and Alpha secretase.
Particularly relevant to Amyloid precursor protein secretase is his body of work in Amyloid precursor protein.
As part of his studies on Amyloid precursor protein secretase, Gopal Thinakaran often connects relevant areas like Biochemistry.
His study in Amyloid is interdisciplinary in nature, drawing from both Biophysics, P3 peptide and Signal transducing adaptor protein.
Between 2014 and 2020, his most popular works were:
- A Greek Tragedy: the Growing Complexity of Alzheimer Amyloid Precursor Protein Proteolysis (93 citations)
- Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer's disease. (85 citations)
- APP Receptor? To Be or Not To Be (63 citations)
In his most recent research, the most cited papers focused on:
Gopal Thinakaran focuses on Amyloid precursor protein, Cell biology, Neuroscience, Receptor and Alzheimer's disease.
Gopal Thinakaran has included themes like Biochemistry and Protease in his Amyloid precursor protein study.
His Biochemistry study combines topics in areas such as Dynein, Microtubule, P3 peptide and Axoplasmic transport.
The various areas that Gopal Thinakaran examines in his Neuroscience study include Disease etiology, Disease pathogenesis, Function, Cell surface receptor and Signaling proteins.
His work carried out in the field of Alzheimer's disease brings together such families of science as Human brain, Multiple sclerosis and Alternative splicing.
His Amyloid precursor protein secretase study incorporates themes from Alpha secretase, Presenilin, Proteolysis and Amyloid.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
