World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
97
Citations
45676
World Ranking
1724
National Ranking
958

Medicine

D-Index
100
Citations
47716
World Ranking
8159
National Ranking
4231

Overview

Sam Gandy is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research primarily focuses on the field of medicine, with significant contributions in physiology, neurology, epidemiology, molecular biology, and toxicology.

The scientist's main topics of work include:

  • Alzheimer's disease research and treatments
  • Traumatic Brain Injury Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Occupational Health and Performance
  • Dementia and Cognitive Impairment Research
  • Posttraumatic Stress Disorder Research

Sam Gandy has published extensively in several venues. Frequent publication venues include:

  • Alzheimer's & Dementia
  • Journal of Alzheimer's Disease
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Neurodegeneration
  • Alzheimer's & Dementia Diagnosis Assessment & Disease Monitoring

Notable recent papers authored or co-authored by Sam Gandy include:

  • "Molecular subtyping of Alzheimer's disease using RNA sequencing data reveals novel mechanisms and targets" (2021) published in Science Advances
  • "Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease" (2020) published in Neuron
  • "Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease" (2020) published in Nature Communications
  • "Microglial TYROBP/DAP12 in Alzheimer's disease: Transduction of physiological and pathological signals across TREM2" (2022) published in Molecular Neurodegeneration
  • "VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice" (2020) published in Molecular Neurodegeneration

Frequent co-authors collaborating with Sam Gandy include:

  • Michelle E. Ehrlich
  • Mary Sano
  • Sean Clouston
  • Benjamin J. Luft
  • Evelyn J. Bromet

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo

    David R. Borchelt;Gopal Thinakaran;Christopher B. Eckman;Christopher B. Eckman;Michael K. Lee

  • Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

    Steven E. Arnold;Zoe Arvanitakis;Shannon L. Macauley-Rambach;Aaron M. Koenig

  • ENDOPROTEOLYSIS OF PRESENILIN 1 AND ACCUMULATION OF PROCESSED DERIVATIVES IN VIVO

    Gopal Thinakaran;David R Borchelt;Michael K Lee;Hilda H Slunt

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Apolipoprotein E epsilon4 associated with chronic traumatic brain injury in boxing

    Barry D. Jordan;Norman R. Relkin;Lisa D. Ravdin;Alan R. Jacobs

  • Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor.

    Joseph D. Buxbaum;Masaki Oishi;Henry I. Chen;Ronit Pinkas-Kramarski

  • Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus.

    Benjamin Readhead;Jean Vianney Haure-Mirande;Cory C. Funk;Matthew A. Richards

  • Neuronal SIRT1 Activation as a Novel Mechanism Underlying the Prevention of Alzheimer Disease Amyloid Neuropathology by Calorie Restriction

    Weiping Qin;Tianle Yang;Lap Ho;Lap Ho;Zhong Zhao

  • Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides.

    Huaxi Xu;Gunnar K. Gouras;Jeffrey P. Greenfield;Bruno Vincent

  • The role of cerebral amyloid β accumulation in common forms of Alzheimer disease

    Sam Gandy

  • Formation and maintenance of Alzheimer’s disease beta-amyloid plaques in the absence of microglia

    Stefan Grathwohl;R.E. Kälin;T. Bolmont;S. Prokop

  • Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation.

    J D Buxbaum;S E Gandy;P Cicchetti;M E Ehrlich

  • Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging.

    J Näslund;A Schierhorn;U Hellman;L Lannfelt

  • Protein Topology of Presenilin 1

    Andrew Doan;Gopal Thinakaran;David R Borchelt;Hilda H Slunt

  • Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease

    Ian Martins;Eugene Hone;Eugene Hone;Jonathan Foster;Jonathan Foster;Susanna Sunram-Lea

  • Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein.

    A.B. Jaffe;C.D. Toran-Allerand;P. Greengard;S.E. Gandy

  • Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein

    Gregg L. Caporaso;Samuel E. Gandy;Joseph D. Buxbaum;Triprayar V. Ramabhadran

  • The Profile of Soluble Amyloid β Protein in Cultured Cell Media: DETECTION AND QUANTIFICATION OF AMYLOID β PROTEIN AND VARIANTS BY IMMUNOPRECIPITATION-MASS SPECTROMETRY *

    Rong Wang;David Sweeney;Samuel E. Gandy;Sangram S. Sisodia

  • Traumatic brain injury: football, warfare, and long-term effects.

    Steven T DeKosky;Milos D Ikonomovic;Sam Gandy

Frequent Co-Authors

Michelle E. Ehrlich
Michelle E. Ehrlich Icahn School of Medicine at Mount Sinai
Ralph N. Martins
Ralph N. Martins Edith Cowan University
Mary Sano
Mary Sano Icahn School of Medicine at Mount Sinai
Paul Greengard
Paul Greengard Rockefeller University
Vahram Haroutunian
Vahram Haroutunian Icahn School of Medicine at Mount Sinai
Joseph D. Buxbaum
Joseph D. Buxbaum Icahn School of Medicine at Mount Sinai
Toshiharu Suzuki
Toshiharu Suzuki Hokkaido University
Kevin Taddei
Kevin Taddei Edith Cowan University
Eric E. Schadt
Eric E. Schadt Icahn School of Medicine at Mount Sinai
Patrick R. Hof
Patrick R. Hof Icahn School of Medicine at Mount Sinai

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring an online degree in Biology or Biochemistry opens many doors in the growing healthcare and science fields. Students interested in specialized technical roles can benefit from radiology tech online programs, which provide affordable and flexible routes to work with medical imaging technology.

If nutrition and patient health management are your passion, the best dietetics programs online can help you become a registered dietitian. Those seeking hands-on patient care experience may consider online medical assistant programs that accept financial aid, making entry into healthcare careers more accessible.

As your career progresses, you might want to advance from assisting roles to higher levels of patient care. The medical assistant to lpn bridge program online is a practical step, designed for medical assistants ready to move into licensed nursing positions.

Whether your interests lie in laboratory research, clinical practice, or patient support, there are flexible and affordable online pathways that align with your goals in biology and biochemistry.

Best Scientists Citing Sam Gandy

Trending Scientists

Recently Published Articles