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Biology and Biochemistry

D-Index
50
Citations
9723
World Ranking
17582
National Ranking
7212

Overview

Amanda E. Toland is affiliated with The Ohio State University in the United States. Their research spans multiple specialized fields within the broader areas of biochemistry, genetics, molecular biology, and medicine. The scientist has contributed extensively to genetics and oncology, with notable focus on cancer research and molecular biology as subfields.

The main topics covered in their work include:

  • BRCA gene mutations in cancer
  • Genetic factors in colorectal cancer
  • Cancer genomics and diagnostics
  • Colorectal cancer screening and detection
  • Genomics and rare diseases
  • Genetic associations and epidemiology
  • Colorectal cancer treatments and studies

Frequently published venues reflecting the scope of their research are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • UNC Libraries
  • British Journal of Dermatology
  • The American Journal of Human Genetics

Amanda E. Toland collaborates regularly with several scientists, demonstrating interdisciplinary research efforts. Their most frequent co-authors include:

  • Tabitha A. Harrison
  • Peter T. Campbell
  • Marc J. Gunter
  • Daniel D. Buchanan
  • Michael Hoffmeister

Highlighted recent papers from their research portfolio include:

  • Implementation of Germline Testing for Prostate Cancer: Philadelphia Prostate Cancer Consensus Conference 2019, 2020, Journal of Clinical Oncology
  • Pharmacogenomics: Driving Personalized Medicine, 2023, Pharmacological Reviews
  • Genetic architectures of proximal and distal colorectal cancer are partly distinct, 2021, Gut
  • Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants, 2020, JAMA Oncology
  • Evidence-based recommendations for gene-specific ACMG/AMP variant classification from the ClinGen ENIGMA BRCA1 and BRCA2 Variant Curation Expert Panel, 2024, The American Journal of Human Genetics

Best Publications

  • Large-scale genotyping identifies 41 new loci associated with breast cancer risk

    Kyriaki Michailidou;Per Hall;Anna Gonzalez-Neira;Maya Ghoussaini

  • Breast-Cancer Risk in Families with Mutations in PALB2

    A. C. Antoniou;S. Casadei;T. Heikkinen;D. Barrowdale

  • Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).

    Nasim Mavaddat;Daniel Barrowdale;Irene L. Andrulis;Susan M. Domchek

  • Association Between BRCA1 and BRCA2 Mutations and Survival in Women with Invasive Epithelial Ovarian Cancer

    Kelly L. Bolton;Kelly L. Bolton;Georgia Chenevix-Trench;Cindy Goh;Siegal Sadetzki

  • Inherited Mutations in 17 Breast Cancer Susceptibility Genes Among a Large Triple-Negative Breast Cancer Cohort Unselected for Family History of Breast Cancer

    Fergus J. Couch;Steven N. Hart;Priyanka Sharma;Amanda Ewart Toland

  • Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

    Kyriaki Michailidou;Jonathan Beesley;Sara Lindstrom;Sander Canisius

  • Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

    Nasim Mavaddat;Paul D.P. Pharoah;Kyriaki Michailidou;Jonathan Tyrer

  • MicroRNA related polymorphisms and breast cancer risk

    Sofia Khan;Dario Greco;Dario Greco;Kyriaki Michailidou;Roger L. Milne;Roger L. Milne

  • Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

    Timothy R. Rebbeck;Nandita Mitra;Fei Wan;Olga M. Sinilnikova

  • Discovery of common and rare genetic risk variants for colorectal cancer

    Jeroen R. Huyghe;Stephanie A. Bien;Tabitha A. Harrison;Hyun Min Kang

  • Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

    Felix R. Day;Katherine S. Ruth;Deborah J Thompson;Kathryn L. Lunetta

  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

    Catherine M Phelan;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Jonathan P Tyrer;Siddhartha P Kar

  • A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

    Antonis C. Antoniou;Xianshu Wang;Zachary S. Fredericksen;Lesley McGuffog

  • Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

    Roger L Milne;Roger L Milne;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Kyriaki Michailidou;Kyriaki Michailidou;Jonathan Beesley

  • Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

    Haoyu Zhang;Haoyu Zhang;Thomas U. Ahearn;Julie Lecarpentier;Daniel Barnes

  • Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

    Fergus J. Couch;Xianshu Wang;Lesley McGuffog;Andrew Lee

  • Evaluation of polygenic risk scores for breast and ovarian cancer risk prediction in BRCA1 and BRCA2 mutation carriers

    Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Lesley McGuffog;Daniel Barrowdale;Andrew Lee

  • Elastin Point Mutations Cause an Obstructive Vascular Disease, Supravalvular Aortic Stenosis

    Dean Y. Li;Amanda E. Toland;Beth B. Boak;Donald L. Atkinson

  • Large-scale genomic analyses link reproductive ageing to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

    Felix R. Day;Katherine S. Ruth;Deborah J. Thompson;Kathryn L. Lunetta

  • Discovery of common and rare genetic risk variants for colorectal cancer

    Jeroen R. Huyghe;Stephanie A. Bien;Tabitha A. Harrison;Hyun Min Kang

Frequent Co-Authors

Irene L. Andrulis
Irene L. Andrulis University of Toronto
Fergus J. Couch
Fergus J. Couch Mayo Clinic
Douglas F. Easton
Douglas F. Easton University of Cambridge
Graham G. Giles
Graham G. Giles University of Melbourne
Melissa C. Southey
Melissa C. Southey Monash University
Roger L. Milne
Roger L. Milne Cancer Council Victoria
Georgia Chenevix-Trench
Georgia Chenevix-Trench QIMR Berghofer Medical Research Institute
Heli Nevanlinna
Heli Nevanlinna University of Helsinki
Hiltrud Brauch
Hiltrud Brauch German Cancer Research Center
Javier Benitez
Javier Benitez Instituto de Salud Carlos III

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