Ian A. Trounce

Overview

Best Publications

• Decline in skeletal muscle mitochondrial respiratory chain function : possible factor in ageing

  Ian Trounce;Edward Byrne;Sangkot Marzuki

  1056
  Citations

• Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines.

  Ian A. Trounce;Yoon L. Kim;Albert S. Jun;Douglas C. Wallace

  854
  Citations

• Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion.

  Scott W. Ballinger;John M. Shoffner;Ellis V. Hedaya;Ian Trounce

  847
  Citations

• A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator

  Brett H. Graham;Katrina G. Waymire;Barbara Cottrell;Ian A. Trounce

  664
  Citations

• Copper-Dependent Inhibition of Human Cytochrome c Oxidase by a Dimeric Conformer of Amyloid-β1-42

  Peter J. Crouch;Rachel Blake;James A. Duce;Giuseppe D. Ciccotosto

  398
  Citations

• Oxidative stress and mitochondrial dysfunction in glaucoma.

  Vicki Chrysostomou;Fatemeh Rezania;Ian A Trounce;Jonathan G Crowston

  393
  Citations

• Functional analysis of lymphoblast and cybrid mitochondria containing the 3460, 11778, or 14484 Leber's hereditary optic neuropathy mitochondrial DNA mutation

  Michael D. Brown;Ian A. Trounce;Albert S. Jun;Jon C. Allen

  356
  Citations

• Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming

  Martin Picard;Jiangwen Zhang;Saege Hancock;Olga Derbeneva

  307
  Citations

• Mitochondrial DNA mutations in human degenerative diseases and aging

  Douglas C. Wallace;John M. Shoffner;Ian Trounce;Michael D. Brown

  300
  Citations

• Mitochondrial dysfunction and glaucoma.

  George Y. X. Kong;Nicole J. Van Bergen;Ian A. Trounce;Jonathan G. Crowston

  293
  Citations

• Cytoplasmic transfer of the mtDNA nt 8993 T-->G (ATP6) point mutation associated with Leigh syndrome into mtDNA-less cells demonstrates cosegregation with a decrease in state III respiration and ADP/O ratio

  Ian Trounce;Stephanie Neill;Douglas C. Wallace

  264
  Citations

• The role of glia, mitochondria, and the immune system in glaucoma.

  Gülgün Tezel;Tamir Ben-Hur;Gary E. Gibson;Beth Stevens

  214
  Citations

• Mitochondrial dysfunction and complications associated with diabetes

  Rachel Blake;Ian A. Trounce;Ian A. Trounce

  213
  Citations

• Use of Transmitochondrial Cybrids To Assign a Complex I Defect to the Mitochondrial DNA-Encoded NADH Dehydrogenase Subunit 6 Gene Mutation at Nucleotide Pair 14459 That Causes Leber Hereditary Optic Neuropathy and Dystonia

  Albert S. Jun;Ian A. Trounce;Michael D. Brown;John M. Shoffner

  213
  Citations

• Recharacterization of the RGC-5 Retinal Ganglion Cell Line

  Nicole J. Van Bergen;John P. M. Wood;Glyn Chidlow;Ian A. Trounce

  208
  Citations

• Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A

  Richard David William Kelly;Arsalan Mahmud;Matthew McKenzie;Ian Trounce

  207
  Citations

• Mitochondrial dysfunction in glaucoma and emerging bioenergetic therapies

  Shanjean Lee;Nicole J Van Bergen;George Y Kong;Vicki Chrysostomou

  183
  Citations

• Deletion of Skeletal Muscle SOCS3 Prevents Insulin Resistance in Obesity

  Sebastian Beck Jorgensen;Sebastian Beck Jorgensen;Hayley M. O’Neill;Hayley M. O’Neill;Lykke Sylow;Jane Honeyman

  163
  Citations

• Measurement of Systemic Mitochondrial Function in Advanced Primary Open-Angle Glaucoma and Leber Hereditary Optic Neuropathy.

  Nicole J Van Bergen;Jonathan G. Crowston;Jamie E. Craig;Kathryn P. Burdon

  151
  Citations

• Improvement in inner retinal function in glaucoma with nicotinamide (vitamin B3) supplementation: A crossover randomized clinical trial.

  Flora Hui;Jessica Tang;Pete A Williams;Myra B McGuinness

  150
  Citations