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Biology and Biochemistry
Australia
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
29275
World Ranking
3285
National Ranking
72

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Australia Leader Award

Overview

Kevin J. Barnham is affiliated with the Florey Institute of Neuroscience and Mental Health in Australia. Their research spans multiple fields within the life sciences, focusing primarily on biochemical, genetic, and molecular biology approaches intersecting with medicine.

The main fields of their scientific work include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

They have contributed extensively to several subfields such as:

  • Molecular Biology
  • Neurology
  • Cancer Research
  • Physiology
  • Cellular and Molecular Neuroscience

Their research topics cover a range of neurological and molecular areas, specifically:

  • Extracellular vesicles in disease
  • MicroRNA in disease regulation
  • Alzheimer's disease research and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurological disorders and treatments
  • Dementia and Cognitive Impairment Research

Among their recent papers are:

  • Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture (2020, Nature Communications)
  • Characterization of brain-derived extracellular vesicle lipids in Alzheimer's disease (2021, Journal of Extracellular Vesicles)
  • Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer's disease (2021, Nature Communications)
  • Small RNA fingerprinting of Alzheimer's disease frontal cortex extracellular vesicles and their comparison with peripheral extracellular vesicles (2020, Journal of Extracellular Vesicles)
  • Parkinsonism as a Third Wave of the COVID-19 Pandemic? (2020, Journal of Parkinson's Disease)

The scientist frequently collaborates with other researchers including:

  • Colin L. Masters
  • Laura J. Vella
  • Ashley I. Bush
  • Catriona McLean
  • Christopher Fowler

The venues where Kevin J. Barnham publishes their work commonly include:

  • Alzheimer's & Dementia
  • Nature Communications
  • Journal of Extracellular Vesicles
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Cambridge Structural Database

Best Publications

  • Neurodegenerative diseases and oxidative stress.

    Kevin J. Barnham;Colin L. Masters;Ashley I. Bush;Ashley I. Bush

  • Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

    Robert A Cherny;Craig S Atwood;Michel E Xilinas;Danielle N Gray

  • Alzheimer's Disease Amyloid-β Binds Copper and Zinc to Generate an Allosterically Ordered Membrane-penetrating Structure Containing Superoxide Dismutase-like Subunits

    Cyril C. Curtain;Feda Ali;Irene Volitakis;Robert A. Cherny

  • Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ

    Paul A. Adlard;Robert A. Cherny;Robert A. Cherny;David I. Finkelstein;David I. Finkelstein;Elisabeth Gautier

  • Metals in Alzheimer's and Parkinson's Diseases

    Kevin J Barnham;Ashley I Bush;Ashley I Bush

  • Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease

    James A. Duce;Andrew Tsatsanis;Michael A. Cater;Simon A. James

  • The redox chemistry of the Alzheimer's disease amyloid β peptide

    Danielle G. Smith;Roberto Cappai;Kevin J. Barnham;Kevin J. Barnham

  • Cisplatin Binding Sites on Human Albumin

    Andrei I. Ivanov;John Christodoulou;John A. Parkinson;Kevin J. Barnham

  • Biological metals and metal-targeting compounds in major neurodegenerative diseases.

    Kevin J. Barnham;Ashley I. Bush;Ashley I. Bush;Ashley I. Bush

  • 18F-THK523: a novel in vivo tau imaging ligand for Alzheimer’s disease

    Michelle T Fodero-Tavoletti;Nobuyuki Okamura;Shozo Furumoto;Rachel S Mulligan

  • Copper-Dependent Inhibition of Human Cytochrome c Oxidase by a Dimeric Conformer of Amyloid-β1-42

    Peter J. Crouch;Rachel Blake;James A. Duce;Giuseppe D. Ciccotosto

  • Structure of the Alzheimer's Disease Amyloid Precursor Protein Copper Binding Domain A REGULATOR OF NEURONAL COPPER HOMEOSTASIS

    Kevin J. Barnham;William J. McKinstry;Gerd Multhaup;Denise Galatis

  • Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity.

    Anthony R White;Anthony R White;Tai Du;Tai Du;Katrina M Laughton;Irene Volitakis

  • Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126

    Michael F. Jobling;Xudong Huang;Leanne R. Stewart;Kevin J. Barnham

  • Increasing Cu bioavailability inhibits Aβ oligomers and tau phosphorylation

    Peter J. Crouch;Lin Wai Hung;Paul A. Adlard;Mikhalina Cortes

  • Dopamine promotes α-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway

    Roberto Cappai;Su-Ling Leck;Deborah J Tew;Deborah J Tew;Nicholas A Williamson

  • Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease β-amyloid

    Kevin J. Barnham;Fredrik Haeffner;Giuseppe D. Ciccotosto;Cyril C. Curtain

  • SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid β protein oligomerization and memory loss in mouse model of Alzheimer disease.

    Kazuma Murakami;Nakaba Murata;Yoshihiro Noda;Shoichi Tahara

  • Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics

    Colin L. Masters;Roberto Cappai;Roberto Cappai;Kevin J. Barnham;Kevin J. Barnham;Victor L. Villemagne;Victor L. Villemagne

  • Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes.

    Robyn A. Sharples;Laura J. Vella;Rebecca M. Nisbet;Ryan Naylor

Frequent Co-Authors

Colin L. Masters
Colin L. Masters University of Melbourne
Roberto Cappai
Roberto Cappai University of Melbourne
Ashley I. Bush
Ashley I. Bush Florey Institute of Neuroscience and Mental Health
Robert A. Cherny
Robert A. Cherny Florey Institute of Neuroscience and Mental Health
Anthony R. White
Anthony R. White QIMR Berghofer Medical Research Institute
Victor L. Villemagne
Victor L. Villemagne University of Pittsburgh
Andrew F. Hill
Andrew F. Hill Victoria University
Paul S. Donnelly
Paul S. Donnelly University of Melbourne
Paul A. Adlard
Paul A. Adlard Florey Institute of Neuroscience and Mental Health
Catriona McLean
Catriona McLean The Alfred Hospital

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