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Immunology

D-Index
49
Citations
17018
World Ranking
4294
National Ranking
1951

Overview

Michael R. Comeau is affiliated with Silverback Therapeutics in the United States. Their research primarily focuses on immunology and microbiology, with a specialization in immunology. Their work spans subfields including immunology and allergy, otorhinolaryngology, cognitive neuroscience, and sensory systems.

The scientist's research topics include:

  • Immune cells in cancer
  • Immunotherapy and Immune Responses
  • Immune Cell Function and Interaction
  • Cell Adhesion Molecules Research
  • Ear Surgery and Otitis Media
  • Hearing Loss and Rehabilitation
  • Hearing, Cochlea, Tinnitus, Genetics

Their publication record features several recent papers, including:

  • SBT6050, a HER2-directed TLR8 therapeutic, as a systemically administered, tumor-targeted human myeloid cell agonist. (2020, Journal of Clinical Oncology)
  • Abstract 1858: SBT6290, a systemically administered Nectin4-directed TLR8 ImmunoTAC™ product candidate, is designed for tumor-localized activation of myeloid cells (2021, Cancer Research)
  • Clinical consensus document for fitting non-surgical transcutaneous bone conduction hearing devices to children (2021, International Journal of Audiology)
  • Abstract 4537: SBT6050, a HER2-directed TLR8 ImmunoTAC™therapeutic, is a potent human myeloid cell agonist that provides opportunity for single agent clinical activity (2020, Cancer Research)
  • 712 SBT6290, a systemically administered Nectin-4-directed TLR8 ImmunoTAC (TM) therapeutic, is a potent human myeloid cell agonist for the treatment of Nectin-4-expressing tumors (2020, Regular and Young Investigator Award Abstracts)

Michael R. Comeau frequently publishes in these venues:

  • Cancer Research
  • Regular and Young Investigator Award Abstracts
  • Journal of Clinical Oncology
  • International Journal of Audiology
  • University Libraries (University of Maryland)

They collaborate regularly with several coauthors, including:

  • Heather Metz
  • Monica Childs
  • Jamie Brevik
  • Damion Winship
  • Jenny C. Chang

Best Publications

  • Herpesvirus saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor.

    Zhengbin Yao;William C. Fanslow;Michael F. Seldin;Anne Marie Rousseau

  • The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor

    David P. Gearing;Michael R. Comeau;Della J. Friend;Steven D. Gimpel

  • Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice.

    Baohua Zhou;Michael R Comeau;Thibaut De Smedt;H Denny Liggitt

  • Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells

    Zoulfia Allakhverdi;Michael R. Comeau;Heidi K. Jessup;Bo-Rin Park Yoon

  • Effects of an Anti-TSLP Antibody on Allergen-Induced Asthmatic Responses

    Gail M Gauvreau;Paul M O'Byrne;Louis-Philippe Boulet;Ying Wang

  • MHC class II–dependent basophil–CD4 + T cell interactions promote T H 2 cytokine–dependent immunity

    Jacqueline G Perrigoue;Steven A Saenz;Mark C Siracusa;Eric J Allenspach

  • IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells.

    Molly D. Smithgall;Michael R. Comeau;Bo-Rin Park Yoon;Dawn Kaufman

  • TSLP elicits IL-33–independent innate lymphoid cell responses to promote skin inflammation

    Brian S. Kim;Mark C. Siracusa;Steven A. Saenz;Mario Noti

  • Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin

    Jane Yoo;Miyuki Omori;Dora Gyarmati;Baohua Zhou

  • Cutting Edge: The ST2 Ligand IL-33 Potently Activates and Drives Maturation of Human Mast Cells

    Zoulfia Allakhverdi;Dirk E. Smith;Michael R. Comeau;Guy Delespesse

  • TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation

    Mark C. Siracusa;Steven A. Saenz;David A. Hill;Brian S. Kim

  • Thymic stromal lymphopoietin–elicited basophil responses promote eosinophilic esophagitis

    Mario Noti;Elia D.Tait Wojno;Brian S. Kim;Mark C. Siracusa

  • TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis

    Betsy C. Taylor;Colby Zaph;Amy E. Troy;Yurong Du

  • Identification of Functional Roles for Both IL-17RB and IL-17RA in Mediating IL-25-Induced Activities

    Erika A. Rickel;Lori A. Siegel;Bo-Rin Park Yoon;James B. Rottman

  • 'Agranular CD4+ CD56+ hematodermic neoplasm' (blastic NK-cell lymphoma) originates from a population of CD56+ precursor cells related to plasmacytoid monocytes.

    Tony Petrella;Michael R Comeau;Marc Maynadié;Gérard Couillault

  • Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin-basophil axis.

    Mario Noti;Brian S. Kim;Mark C. Siracusa;Gregory D. Rak

  • Epstein-Barr virus uses HLA class II as a cofactor for infection of B lymphocytes

    Unknown

  • A Poxvirus-Encoded Semaphorin Induces Cytokine Production from Monocytes and Binds to a Novel Cellular Semaphorin Receptor, VESPR

    Michael R Comeau;Richard Johnson;Robert F DuBose;Melissa Petersen

  • CD34+ hemopoietic progenitor cells are potent effectors of allergic inflammation.

    Zoulfia Allakhverdi;Michael R. Comeau;Dirk E. Smith;Dean Toy

  • Thymic stromal lymphopoietin activity is increased in nasal polyps of patients with chronic rhinosinusitis

    Deepti R. Nagarkar;Julie A. Poposki;Bruce K. Tan;Michael R. Comeau

  • MHC class II-dependent basophil-CD4 + Tc ell interactions promote T H 2 cytokine-dependent

    Jacqueline G Perrigoue;Steven A Saenz;Mark C Siracusa;Eric J Allenspach

Frequent Co-Authors

Steven F. Ziegler
Steven F. Ziegler Virginia Mason Medical Center
David Artis
David Artis Cornell University
Hakon Hakonarson
Hakon Hakonarson Children's Hospital of Philadelphia
Patrick M.A. Sleiman
Patrick M.A. Sleiman Children's Hospital of Philadelphia
Guy Delespesse
Guy Delespesse University of Montreal
Jonathan M. Spergel
Jonathan M. Spergel University of Pennsylvania
Brian S. Kim
Brian S. Kim Icahn School of Medicine at Mount Sinai
Atsushi Kato
Atsushi Kato Northwestern University
Daniel J. Campbell
Daniel J. Campbell Virginia Mason Medical Center

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