World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
91
Citations
45728
World Ranking
1021
National Ranking
554

Medicine

D-Index
91
Citations
45757
World Ranking
11539
National Ranking
5917

Overview

Steven F. Ziegler is affiliated with the Virginia Mason Medical Center in the United States. Their research focuses primarily on medicine, with significant contributions to immunology and microbiology. Within these fields, their work spans several specialized subfields including immunology, dermatology, pulmonary and respiratory medicine, physiology, and epidemiology.

Their research covers a range of main topics, notably:

  • IL-33, ST2, and ILC Pathways
  • Immune Cell Function and Interaction
  • Dermatology and Skin Diseases
  • Asthma and respiratory diseases
  • T-cell and B-cell Immunology
  • Respiratory viral infections research
  • Neonatal Respiratory Health Research

Steven F. Ziegler has frequently published in the following venues:

  • The Journal of Immunology (15 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (9 publications)
  • Journal of Allergy and Clinical Immunology (5 publications)
  • Frontiers in Immunology (4 publications)
  • Mucosal Immunology (2 publications)

Notable recent papers include:

  • "Cross-Talk Between Alveolar Macrophages and Lung Epithelial Cells is Essential to Maintain Lung Homeostasis," 2020, Frontiers in Immunology
  • "ILC2 activation by keratinocyte-derived IL-25 drives IL-13 production at sites of allergic skin inflammation," 2020, Journal of Allergy and Clinical Immunology
  • "Targeted deletion of the TSLP receptor reveals cellular mechanisms that promote type 2 airway inflammation," 2020, Mucosal Immunology
  • "TSLP, IL-33, and IL-25: Not just for allergy and helminth infection," 2022, Journal of Allergy and Clinical Immunology
  • "FOXP3 exon 2 controls T reg stability and autoimmunity," 2022, Science Immunology

The scientist has collaborated frequently with a number of co-authors, including:

  • Jason S. Debley (16 joint publications)
  • Phillip P. Domeier (12 joint publications)
  • Teal S. Hallstrand (9 joint publications)
  • Kazushige Obata-Ninomiya (7 joint publications)
  • Kaitlyn A. Barrow (7 joint publications)

Best Publications

  • Systematic localization of common disease-associated variation in regulatory DNA.

    Matthew T. Maurano;Richard Humbert;Eric Rynes;Robert E. Thurman

  • CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

    Weihong Liu;Amy L Putnam;Zhou Xu-yu;Gregory L. Szot

  • Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.

    Brunkow Me;Jeffery Ew;Hjerrild Ka;Paeper B

  • TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function.

    Liang Zhou;Jared E. Lopes;Jared E. Lopes;Mark M. W. Chong;Ivaylo I. Ivanov

  • FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT

    Yongqing Wu;Madhuri Borde;Vigo Heissmeyer;Markus Feuerer

  • FOXP3: Of Mice and Men

    Steven F. Ziegler

  • The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor

    David P. Gearing;Michael R. Comeau;Della J. Friend;Steven D. Gimpel

  • Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor

    Masayuki Noguchi;Yoshiaki Nakamura;Sarah M. Russell;Steven F. Ziegler

  • Defective IL7R expression in T - B + NK + severe combined immunodeficiency

    Anne Puel;Steven F. Ziegler;Rebecca H. Buckley;Warren J. Leonard.

  • Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice.

    Baohua Zhou;Michael R Comeau;Thibaut De Smedt;H Denny Liggitt

  • Scurfin (FOXP3) Acts as a Repressor of Transcription and Regulates T Cell Activation

    Lisa A. Schubert;Eric Jeffery;Yi Zhang;Fred Ramsdell

  • The activation antigen CD69

    Steven F. Ziegler;Fred Ramsdell;Mark R. Alderson

  • Cloning of the human and murine interleukin-7 receptors: Demonstration of a soluble form and homology to a new receptor superfamily

    Raymond G. Goodwin;Della Friend;Steven F. Ziegler;Rita Jerzy

  • Sensing the outside world: TSLP regulates barrier immunity

    Steven F Ziegler;David Artis

  • Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin

    Jane Yoo;Miyuki Omori;Dora Gyarmati;Baohua Zhou

  • Cutting Edge: Estrogen Drives Expansion of the CD4+CD25+ Regulatory T Cell Compartment

    Magdalena J. Polanczyk;Bryan D. Carson;Bryan D. Carson;Sandhya Subramanian;Michael Afentoulis

  • TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation

    Mark C. Siracusa;Steven A. Saenz;David A. Hill;Brian S. Kim

  • Decreased FOXP3 levels in multiple sclerosis patients.

    Jianya Huan;Nicole Culbertson;Nicole Culbertson;Leslie Spencer;Leslie Spencer;Richard Bartholomew

  • Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFκB

    Hai-Chon Lee;Steven F. Ziegler;Steven F. Ziegler

  • Epithelial cell–derived cytokines: more than just signaling the alarm

    Florence Roan;Kazushige Obata-Ninomiya;Steven F. Ziegler;Steven F. Ziegler

  • Cutting Edge: Estrogen Drives Expansion of the CD4CD25 Regulatory T Cell Compartment 1

    Magdalena J. Polanczyk;Bryan D. Carson;Sandhya Subramanian;Michael Afentoulis

  • Induction of FoxP3 and acquisition of T regulatory activity by stimulated

    Deborah J. Kasprowicz;Vivian H. Gersuk;Angéle Bènard;Megan Van Landeghen

Frequent Co-Authors

Michael R. Comeau
Michael R. Comeau Silverback Therapeutics
Jane H. Buckner
Jane H. Buckner Virginia Mason Medical Center
Daniel J. Campbell
Daniel J. Campbell Virginia Mason Medical Center
David J. Rawlings
David J. Rawlings Seattle Children's Hospital
Raif S. Geha
Raif S. Geha Boston Children's Hospital
Roger M. Perlmutter
Roger M. Perlmutter University of Washington
Teal S. Hallstrand
Teal S. Hallstrand University of Washington
Andrew G. Farr
Andrew G. Farr University of Washington
Charles W. Frevert
Charles W. Frevert University of Washington
Heinz Baumann
Heinz Baumann Roswell Park Cancer Institute

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