What is he best known for?
The fields of study he is best known for:
- Gene
- Signal transduction
- Immune system
Roger M. Perlmutter mainly investigates Cell biology, T-cell receptor, Signal transduction, Cancer research and T lymphocyte.
His T-cell receptor research incorporates elements of GTP-binding protein regulators, IL-2 receptor, Cellular differentiation, Mitogen-activated protein kinase and Receptor.
His research on Signal transduction frequently links to adjacent areas such as Kinase.
His study in Cancer research is interdisciplinary in nature, drawing from both Neoplastic cell, Proto-oncogene tyrosine-protein kinase Src and Protein kinase A.
Roger M. Perlmutter has included themes like FYN, T cell, Thymocyte, Molecular biology and ZAP70 in his T lymphocyte study.
Roger M. Perlmutter studied Thymocyte and Transgene that intersect with CD8.
His most cited work include:
- A Syndrome of Multiorgan Hyperplasia with Features of Gigantism, Tumorigenesis, and Female Sterility in p27Kip1-Deficient Mice (1389 citations)
- Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs (512 citations)
- Early restriction of the human antibody repertoire (473 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Cell biology, Molecular biology, Signal transduction, Tyrosine kinase and T cell.
The Cell biology study combines topics in areas such as Biochemistry, ZAP70, T-cell receptor and Antigen.
Roger M. Perlmutter combines subjects such as Gene, Transgene, B cell, Promoter and Binding site with his study of Molecular biology.
His work carried out in the field of Signal transduction brings together such families of science as Cellular differentiation, Thymocyte and Kinase.
His Tyrosine kinase study incorporates themes from Cancer research, Receptor tyrosine kinase, Gene rearrangement and Proto-oncogene tyrosine-protein kinase Src.
As a part of the same scientific family, Roger M. Perlmutter mostly works in the field of T cell, focusing on Intracellular and, on occasion, Mitogen-activated protein kinase.
He most often published in these fields:
- Cell biology (49.46%)
- Molecular biology (40.86%)
- Signal transduction (29.03%)
What were the highlights of his more recent work (between 1997-2007)?
- T cell (33.33%)
- Cell biology (49.46%)
- Molecular biology (40.86%)
In recent papers he was focusing on the following fields of study:
Roger M. Perlmutter focuses on T cell, Cell biology, Molecular biology, T-cell receptor and ZAP70.
His biological study focuses on Thymocyte.
His Cell biology research includes themes of Biochemistry, Cellular differentiation, B cell and Ligand.
As part of the same scientific family, Roger M. Perlmutter usually focuses on Cellular differentiation, concentrating on Cancer research and intersecting with Transcription.
His study in Molecular biology is interdisciplinary in nature, drawing from both Zinc finger, Transactivation, Enhancer, Promoter and Binding site.
His research in T-cell receptor intersects with topics in Receptor, Lymphocyte and Intraepithelial lymphocyte.
Between 1997 and 2007, his most popular works were:
- T cell antigen receptor-mediated activation of the Ras/mitogen-activated protein kinase pathway controls interleukin 4 receptor function and type-2 helper T cell differentiation (194 citations)
- Presenilin-dependent γ-secretase activity modulates thymocyte development (151 citations)
- Control of B Cell Production by the Adaptor Protein Lnk: Definition of a Conserved Family of Signal-Modulating Proteins (120 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Immune system
- Genetics
Roger M. Perlmutter mostly deals with Cell biology, Biochemistry, T cell, Cellular differentiation and Intracellular.
His Cell biology study is mostly concerned with JAK-STAT signaling pathway and Notch signaling pathway.
His JAK-STAT signaling pathway research incorporates elements of IL-2 receptor, T-cell receptor, CD40, ZAP70 and c-Raf.
His research combines Thymocyte and Notch signaling pathway.
The study incorporates disciplines such as Signal transducing adaptor protein, Pleckstrin homology domain, Ligand and Immature B-Cells, B cell in addition to Intracellular.
In most of his B cell studies, his work intersects topics such as Bone marrow.
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