D-Index & Metrics Best Publications
Susumu Tonegawa

Susumu Tonegawa

Research.com 2022 Best Scientist Award Badge

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 127 Citations 75,998 252 World Ranking 196 National Ranking 138
Best Scientists D-index 176 Citations 114,397 423 World Ranking 499 National Ranking 332

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Scientist Award

2019 - Distinguished Fellows of the American Association of Immunologists (AAI)

2006 - Fellow of the American Association for the Advancement of Science (AAAS)

1987 - Nobel Prize for his discovery of the genetic principle for generation of antibody diversity

1987 - Albert Lasker Award for Basic Medical Research, Lasker Foundation

1986 - Member of the National Academy of Sciences

1986 - Robert Koch Prize

1984 - Fellow of the American Academy of Arts and Sciences

1983 - Canada Gairdner International Award

1982 - Louisa Gross Horwitz Prize, Columbia University

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Neuroscience

Susumu Tonegawa mostly deals with Neuroscience, Hippocampus, Molecular biology, Hippocampal formation and Synaptic plasticity. His Neuroscience study incorporates themes from NMDA receptor, Neurotransmission and Anatomy. His Hippocampus research incorporates elements of Long-term potentiation, Recall and Postsynaptic potential.

His research investigates the link between Long-term potentiation and topics such as Mutant that cross with problems in Cell biology. His Molecular biology research is multidisciplinary, incorporating perspectives in Immunoglobulin gene, Gene, T lymphocyte, Antigen and Cytotoxic T cell. His work carried out in the field of Memory consolidation brings together such families of science as Long-term memory and Engram.

His most cited work include:

  • Somatic generation of antibody diversity (3423 citations)
  • RAG-1-deficient mice have no mature B and T lymphocytes (2395 citations)
  • The Essential Role of Hippocampal CA1 NMDA Receptor–Dependent Synaptic Plasticity in Spatial Memory (1492 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Neuroscience, Molecular biology, Hippocampal formation, Hippocampus and Gene. His research in Neuroscience intersects with topics in NMDA receptor and Recall. His studies deal with areas such as T lymphocyte, Antigen, T cell, T-cell receptor and Cytotoxic T cell as well as Molecular biology.

His study in Hippocampal formation is interdisciplinary in nature, drawing from both Biological neural network, Neuroplasticity and Episodic memory. Susumu Tonegawa combines subjects such as Synaptic plasticity, Long-term potentiation and Neurotransmission with his study of Hippocampus. His Gene research integrates issues from Immunoglobulin light chain and DNA.

He most often published in these fields:

  • Neuroscience (58.08%)
  • Molecular biology (26.18%)
  • Hippocampal formation (26.38%)

What were the highlights of his more recent work (between 2015-2021)?

  • Neuroscience (58.08%)
  • Engram (21.06%)
  • Hippocampal formation (26.38%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Neuroscience, Engram, Hippocampal formation, Hippocampus and Optogenetics. Neuroscience is represented through his Amygdala, Basolateral amygdala, Episodic memory, Long-term memory and Biological neural network research. The Engram study combines topics in areas such as Fear memory, Recall, Cognitive science and Memory consolidation.

The various areas that he examines in his Memory consolidation study include Synaptic plasticity and Context. His Hippocampal formation research is multidisciplinary, incorporating elements of Published Erratum, MEDLINE and Sensory system. His Optogenetics research focuses on Dendritic spine and how it relates to Retrograde amnesia.

Between 2015 and 2021, his most popular works were:

  • Engrams and circuits crucial for systems consolidation of a memory. (369 citations)
  • Engrams and circuits crucial for systems consolidation of a memory. (369 citations)
  • Ventral CA1 neurons store social memory (247 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Neuron

Susumu Tonegawa mainly focuses on Neuroscience, Engram, Hippocampus, Hippocampal formation and Neuroanatomy of memory. His works in Episodic memory, Long-term memory, Basolateral amygdala, Biological neural network and Contextual memory are all subjects of inquiry into Neuroscience. His Engram research is multidisciplinary, relying on both Dentate gyrus, Context, Memory consolidation, Cognitive science and Neural substrate.

His work in the fields of Hippocampus, such as Pattern completion, intersects with other areas such as State. His research in the fields of Entorhinal cortex overlaps with other disciplines such as Social memory. His Neuroanatomy of memory research incorporates elements of Association, Optogenetics, Subiculum and Nucleus accumbens.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Somatic generation of antibody diversity

Susumu Tonegawa.
Nature (1983)

6271 Citations

RAG-1-deficient mice have no mature B and T lymphocytes

Peter Mombaerts;John Iacomini;Randall Scott Johnson;Karl Herrup.
Cell (1992)

3266 Citations

The Essential Role of Hippocampal CA1 NMDA Receptor–Dependent Synaptic Plasticity in Spatial Memory

Joe Z Tsien;Patricio T Huerta;Susumu Tonegawa.
Cell (1996)

2096 Citations

Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice.

Alcino J. Silva;Charles F. Stevens;Susumu Tonegawa;Yanyan Wang.
Science (1992)

1697 Citations

Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice

Alcino J. Silva;Richard Paylor;Jeanne M. Wehner;Susumu Tonegawa.
Science (1992)

1563 Citations

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene.

Stephen D. Gillies;Sherie L. Morrison;Vernon T. Oi;Susumu Tonegawa.
Cell (1983)

1441 Citations

Reduced stress defense in heme oxygenase 1-deficient cells

Kenneth D. Poss;Susumu Tonegawa.
Proceedings of the National Academy of Sciences of the United States of America (1997)

1437 Citations

Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain

Joe Z Tsien;Dong Feng Chen;David Gerber;Cindy Tom.
Cell (1996)

1325 Citations

Skeletal and CNS defects in Presenilin-1-deficient mice.

Jie Shen;Roderick T Bronson;Dong Feng Chen;Weiming Xia.
Cell (1997)

1314 Citations

BDNF Regulates the Maturation of Inhibition and the Critical Period of Plasticity in Mouse Visual Cortex

Z. Josh Huang;Alfredo Kirkwood;Tommaso Pizzorusso;Vittorio Porciatti.
Cell (1999)

1242 Citations

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