D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 80 Citations 17,903 260 World Ranking 9557 National Ranking 240

Overview

What is he best known for?

The fields of study he is best known for:

  • Cancer
  • Gene
  • Internal medicine

His main research concerns Cancer research, Pathology, DNA methylation, Molecular biology and Carcinogenesis. His Cancer research study integrates concerns from other disciplines, such as Promoter, Gene silencing, Epigenetics and Cadherin. The various areas that Yae Kanai examines in his Pathology study include Mutation and Pancreatic disease, Pancreas.

His DNA methylation study combines topics in areas such as HCCS and Methylation. The Molecular biology study combines topics in areas such as Messenger RNA, Gene expression, Gene and Methyltransferase. His work carried out in the field of Carcinoma brings together such families of science as Cancer, Cell and Lymphatic system.

His most cited work include:

  • Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas. (582 citations)
  • Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer. (394 citations)
  • Cell adhesion system and human cancer morphogenesis (357 citations)

What are the main themes of his work throughout his whole career to date?

Yae Kanai mostly deals with Pathology, Cancer research, DNA methylation, Cancer and Internal medicine. His Pathology study incorporates themes from Pancreatic disease, Pancreas and Adenocarcinoma. His work deals with themes such as Gene expression, Gene and DNA, which intersect with Cancer research.

His DNA methylation research incorporates themes from Carcinogenesis, Molecular biology, Methylation and Epigenetics. Yae Kanai focuses mostly in the field of Molecular biology, narrowing it down to matters related to DNA methyltransferase and, in some cases, DNMT1. His Internal medicine study combines topics from a wide range of disciplines, such as Gastroenterology, Endocrinology and Oncology.

He most often published in these fields:

  • Pathology (40.80%)
  • Cancer research (38.51%)
  • DNA methylation (30.17%)

What were the highlights of his more recent work (between 2014-2021)?

  • Cancer research (38.51%)
  • Pathology (40.80%)
  • DNA methylation (30.17%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cancer research, Pathology, DNA methylation, Internal medicine and Epigenetics. His study in Cancer research is interdisciplinary in nature, drawing from both Intrahepatic Cholangiocarcinoma, Immunology, Organoid, Epigenomics and microRNA. His Pathology research is multidisciplinary, relying on both Tumor microenvironment and Cancer.

His DNA methylation research is multidisciplinary, incorporating perspectives in Carcinogenesis and Molecular biology. His biological study spans a wide range of topics, including Gastroenterology, Endocrinology, Oncology and Mutation. Yae Kanai has included themes like Bisulfite sequencing and Methylation in his Epigenetics study.

Between 2014 and 2021, his most popular works were:

  • Intratumoral tertiary lymphoid organ is a favourable prognosticator in patients with pancreatic cancer. (103 citations)
  • An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma Based on mRNA, microRNA, and DNA Methylation Biomarkers (75 citations)
  • Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy (67 citations)

In his most recent research, the most cited papers focused on:

  • Cancer
  • Gene
  • Internal medicine

His main research concerns Cancer research, Pathology, DNA methylation, Carcinogenesis and Gene. His Cancer research research includes themes of Cell culture, Intrahepatic Cholangiocarcinoma, Immunology, Organoid and Promoter. His research integrates issues of Mutation, KRAS, Gastroenterology and GNAS complex locus in his study of Pathology.

His DNA methylation research is multidisciplinary, relying on both Molecular biology and Carcinoma. His Carcinogenesis research focuses on Epigenetics and how it relates to Glycolysis. His CpG site research also works with subjects such as

  • Endometrial cancer and related Methylation,
  • Cancer cell that intertwine with fields like Biochemistry.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas.

Kenta Yoshiura;Yae Kanai;Atsushi Ochiai;Yutaka Shimoyama.
Proceedings of the National Academy of Sciences of the United States of America (1995)

782 Citations

Cell adhesion system and human cancer morphogenesis

Setsuo Hirohashi;Yae Kanai.
Cancer Science (2003)

544 Citations

Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer.

Y Ino;R Yamazaki-Itoh;K Shimada;M Iwasaki.
British Journal of Cancer (2013)

503 Citations

FOXP3+ regulatory T cells affect the development and progression of hepatocarcinogenesis

Noritoshi Kobayashi;Nobuyoshi Hiraoka;Wataru Yamagami;Hidenori Ojima.
Clinical Cancer Research (2007)

456 Citations

E-cadherin gene mutations in human gastric carcinoma cell lines.

Tatsuya Oda;Yae Kanai;Tsukasa Oyama;Kenta Yoshiura.
Proceedings of the National Academy of Sciences of the United States of America (1994)

376 Citations

Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers.

Tsuyoshi Etoh;Yae Kanai;Saori Ushijima;Tohru Nakagawa.
American Journal of Pathology (2004)

369 Citations

A Truncated β-Catenin Disrupts the Interaction between E-Cadherin and α-Catenin: A Cause of Loss of Intercellular Adhesiveness in Human Cancer Cell Lines

Tsukasa Oyama;Yae Kanai;Atsushi Ochiai;Shingo Akimoto.
Cancer Research (1994)

364 Citations

Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis--A comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens from patients with hepatocellular carcinoma.

Yutaka Kondo;Y. A. E. Kanai;Michiie Sakamoto;Masashi Mizokami.
Hepatology (2000)

364 Citations

Expression of mRNA for DNA methyltransferases and methyl-CpG-binding proteins and DNA methylation status on CpG islands and pericentromeric satellite regions during human hepatocarcinogenesis.

Yoshimasa Saito;Yoshimasa Saito;Yae Kanai;Michiie Sakamoto;Hidetsugu Saito.
Hepatology (2001)

339 Citations

The E-cadherin gene is silenced by CpG methylation in human hepatocellular carcinomas

Yae Kanai;Saori Ushijima;Ai Min Hui;Atsushi Ochiai.
International Journal of Cancer (1997)

324 Citations

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