D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 86 Citations 23,715 423 World Ranking 9285 National Ranking 487

Overview

What is he best known for?

The fields of study he is best known for:

  • Cancer
  • Gene
  • Internal medicine

Heinz Höfler focuses on Pathology, Cancer, Internal medicine, Cancer research and Carcinoma. The concepts of his Pathology study are interwoven with issues in Proteomics and Metastasis. His Cancer study incorporates themes from Missense mutation, Germline mutation and Survival analysis.

His Internal medicine research includes themes of Gastroenterology, Endocrinology and Oncology. His studies in Cancer research integrate themes in fields like Cisplatin, DNA methylation, Carcinogenesis, Mass spectrometry and Breast cancer. His Carcinoma study combines topics from a wide range of disciplines, such as Cadherin, Survival rate, Stomach, Exon and Chromosome instability.

His most cited work include:

  • Mutations of the human E‐cadherin (CDH1) gene (505 citations)
  • Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans. (481 citations)
  • Revised classification of neuroendocrine tumours of the lung, pancreas and gut. (464 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Pathology, Cancer research, Internal medicine, Cancer and Immunohistochemistry. His research in Pathology is mostly concerned with Carcinoma. His study on Cancer research also encompasses disciplines like

  • Molecular biology and DNA most often made with reference to Gene,
  • Cadherin, which have a strong connection to Cell adhesion molecule.

His Internal medicine research includes elements of Gastroenterology and Oncology. Cancer is closely attributed to Survival analysis in his study. His study in the field of Tissue microarray also crosses realms of MALDI imaging.

He most often published in these fields:

  • Pathology (40.24%)
  • Cancer research (25.18%)
  • Internal medicine (22.82%)

What were the highlights of his more recent work (between 2010-2019)?

  • Cancer research (25.18%)
  • Pathology (40.24%)
  • Internal medicine (22.82%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Cancer research, Pathology, Internal medicine, Cancer and Immunohistochemistry. The study incorporates disciplines such as Protein kinase B, Cancer cell, Urokinase receptor, Breast cancer and PTEN in addition to Cancer research. Heinz Höfler interconnects PI3K/AKT/mTOR pathway, Colorectal cancer and Primary tumor, Metastasis in the investigation of issues within Pathology.

His studies deal with areas such as Immunology, Endocrinology and Oncology as well as Internal medicine. His Cancer research is multidisciplinary, incorporating perspectives in Retrospective cohort study, Survival analysis and Notch signaling pathway. As part of one scientific family, Heinz Höfler deals mainly with the area of Immunohistochemistry, narrowing it down to issues related to the Molecular biology, and often Antibody.

Between 2010 and 2019, his most popular works were:

  • Rapamycin extends murine lifespan but has limited effects on aging (252 citations)
  • [German S3-Guideline "Diagnosis and Treatment of Esophagogastric Cancer"] (238 citations)
  • Significance of histopathological tumor regression after neoadjuvant chemotherapy in gastric adenocarcinomas: a summary of 480 cases. (169 citations)

In his most recent research, the most cited papers focused on:

  • Cancer
  • Gene
  • Internal medicine

His primary scientific interests are in Pathology, Cancer, Internal medicine, MALDI imaging and Cancer research. His biological study spans a wide range of topics, including Colorectal cancer, KRAS, Chemotherapy and Intraepithelial neoplasia. Heinz Höfler has included themes like Survival analysis and Retrospective cohort study in his Cancer study.

Heinz Höfler combines subjects such as Endocrinology, Molecular pathology, Gene expression, Oncology and Mutation with his study of Internal medicine. His research in Cancer research intersects with topics in Gene knockdown and Cisplatin. His work carried out in the field of Proteomics brings together such families of science as Immunohistochemistry, Metastasis, Bioinformatics and Adenocarcinoma.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Histomorphology and grading of regression in gastric carcinoma treated with neoadjuvant chemotherapy.

Karen Becker;James D. Mueller;Christoph Schulmacher;Katja Ott.
Cancer (2003)

789 Citations

Mutations of the human E‐cadherin (CDH1) gene

Geert Berx;Karl-Friedrich Becker;Heinz Höfler;Frans van Roy.
Human Mutation (1998)

719 Citations

Revised classification of neuroendocrine tumours of the lung, pancreas and gut.

C. Capella;P. U. Heitz;H. Höfler;E. Solcia.
Virchows Archiv (1995)

676 Citations

Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans.

Natalia S. Pellegata;Leticia Quintanilla-Martinez;Heide Siggelkow;Elenore Samson.
Proceedings of the National Academy of Sciences of the United States of America (2006)

613 Citations

Clinical impact of the plasminogen activation system in tumor invasion and metastasis : Prognostic relevance and target for therapy

M Schmitt;N Harbeck;C Thomssen;O Wilhelm.
Thrombosis and Haemostasis (1997)

560 Citations

HER2 diagnostics in gastric cancer—guideline validation and development of standardized immunohistochemical testing

Josef Rüschoff;Manfred Dietel;Gustavo B Baretton;Susanne Arbogast.
Virchows Archiv (2010)

554 Citations

Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancer

Fritz Jänicke;Manfred Schmitt;Lothar Pache;Kurt Ulm.
Breast Cancer Research and Treatment (1993)

492 Citations

Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele.

Johannes Bange;Dieter Prechtl;Yuri Cheburkin;Katja Specht.
Cancer Research (2002)

357 Citations

Rapamycin extends murine lifespan but has limited effects on aging

Frauke Neff;Diana Flores-Dominguez;Devon P. Ryan;Marion Horsch.
Journal of Clinical Investigation (2013)

348 Citations

Quantification of CK20 gene and protein expression in colorectal cancer by RT-PCR and immunohistochemistry reveals inter- and intratumour heterogeneity.

Silke Lassmann;Markus Bauer;Richie Soong;Joachim Schreglmann.
The Journal of Pathology (2002)

304 Citations

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