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Valerie Gailus-Durner

Valerie Gailus-Durner

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
16009
World Ranking
8649
National Ranking
634

Overview

Valerie Gailus-Durner is affiliated with Helmholtz Zentrum München in Germany. Their research spans multiple fields within biochemistry, genetics, molecular biology, and medicine.

The main fields of study focus on Biochemistry, Genetics and Molecular Biology, with a total of 127 publications, alongside 85 publications in Medicine. Within these disciplines, Gailus-Durner concentrates on subfields such as Molecular Biology, Genetics, Physiology, Endocrinology, Diabetes and Metabolism, and Cell Biology.

The scope of their research includes several main topics, specifically:

  • Adipose Tissue and Metabolism
  • RNA modifications and cancer
  • RNA Research and Splicing
  • Mitochondrial Function and Pathology
  • Metabolism and Genetic Disorders
  • Regulation of Appetite and Obesity
  • Thyroid Disorders and Treatments

Gailus-Durner has published extensively in scientific journals, with frequent appearances in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Mammalian Genome
  • Nature Communications
  • Science Advances
  • Scientific Reports

The following recent papers illustrate the focus and breadth of their work:

  • The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs, 2020, Genes & Development
  • Epigenetic inheritance of diet-induced and sperm-borne mitochondrial RNAs, 2024, Nature
  • Human and mouse essentiality screens as a resource for disease gene discovery, 2020, Nature Communications
  • METTL6 is a tRNA m 3 C methyltransferase that regulates pluripotency and tumor cell growth, 2020, Science Advances
  • Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification, 2020, Nature Communications

Frequent collaborators include:

  • Martin Hrabě de Angelis
  • Helmut Fuchs
  • Birgit Rathkolb
  • Nadine Spielmann
  • Lore Becker

Best Publications

  • High-throughput discovery of novel developmental phenotypes

    Mary E. Dickinson;Ann M. Flenniken;Xiao Ji;Lydia Teboul

  • Cardioprotection and lifespan extension by the natural polyamine spermidine

    Tobias Eisenberg;Mahmoud Abdellatif;Sabrina Schroeder;Uwe Primessnig;Uwe Primessnig

  • A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice

    Wolfgang Enard;Sabine Gehre;Kurt Hammerschmidt;Sabine M. Hölter

  • Aberrant methylation of tRNAs links cellular stress to neuro‐developmental disorders

    Sandra Blanco;Sabine Dietmann;Joana V Flores;Shobbir Hussain

  • A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains

    Michelle M Simon;Simon Greenaway;Jacqueline K White;Helmut Fuchs

  • Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.

    Christoph Kleinschnitz;Henrike Grund;Kirstin Wingler;Melanie Elise Armitage

  • Rapamycin extends murine lifespan but has limited effects on aging

    Frauke Neff;Diana Flores-Dominguez;Devon P. Ryan;Marion Horsch

  • Prevalence of sexual dimorphism in mammalian phenotypic traits

    Natasha A. Karp;Natasha A. Karp;Jeremy Mason;Arthur L. Beaudet;Yoav Benjamini

  • Sum1 and Hst1 repress middle sporulation‐specific gene expression during mitosis in Saccharomyces cerevisiae

    Jianxin Xie;Michael Pierce;Valérie Gailus‐Durner;Marisa Wagner

  • Introducing the German Mouse Clinic: open access platform for standardized phenotyping

    Valérie Gailus-Durner;Helmut Fuchs;Lore Becker;Ines Bolle

  • Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium

    Terrence F Meehan;Nathalie Conte;David B West;Julius O Jacobsen

  • Neuronal 3′,3,5-Triiodothyronine (T3) Uptake and Behavioral Phenotype of Mice Deficient in Mct8, the Neuronal T3 Transporter Mutated in Allan–Herndon–Dudley Syndrome

    Eva K Wirth;Stephan Roth;Cristiane Blechschmidt;Sabine M Hölter

  • Expression Pattern of G Protein-Coupled Receptor 30 in LacZ Reporter Mice

    Jörg Isensee;Luca Meoli;Valeria Zazzu;Christoph Nabzdyk

  • Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease

    Brian Finan;Christoffer Clemmensen;Zhimeng Zhu;Kerstin Stemmer

  • Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts

    Johannes Keller;Philip Catala-Lehnen;Antje K. Huebner;Anke Jeschke

  • Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.

    Martin Hrabě de Angelis;George Nicholson;Mohammed Selloum;Jacqueline K White

  • Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project

    Abdel Ayadi;Marie-Christine Birling;Joanna Bottomley;James Bussell

  • Creatine improves health and survival of mice

    A. Bender;J. Beckers;I. Schneider;S.M. Hölter

  • A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.

    Michael R. Bowl;Michelle M. Simon;Neil J. Ingham;Neil J. Ingham;Simon Greenaway

  • Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss

    Martin H. Schludi;Lore Becker;Lillian Garrett;Tania F. Gendron

Frequent Co-Authors

Helmut Fuchs
Helmut Fuchs Helmholtz Zentrum München
Martin Hrabé de Angelis
Martin Hrabé de Angelis Technical University of Munich
Eckhard Wolf
Eckhard Wolf Ludwig-Maximilians-Universität München
Wolfgang Wurst
Wolfgang Wurst German Center for Neurodegenerative Diseases
Thomas Klopstock
Thomas Klopstock Ludwig-Maximilians-Universität München
Martin Klingenspor
Martin Klingenspor Technical University of Munich
Dirk H. Busch
Dirk H. Busch Technical University of Munich
Johannes Beckers
Johannes Beckers Technical University of Munich
Jochen Graw
Jochen Graw Technical University of Munich
Markus Ollert
Markus Ollert University of Southern Denmark

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