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Biology and Biochemistry

D-Index
73
Citations
20872
World Ranking
5892
National Ranking
420

Overview

Helmut Fuchs is affiliated with Helmholtz Zentrum München in Germany and has contributed extensively to research in the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Their work spans various subfields including Molecular Biology, Genetics, Physiology, Endocrinology, Diabetes and Metabolism, and Cell Biology.

Their research covers a range of main topics, notably:

  • Adipose Tissue and Metabolism
  • RNA Research and Splicing
  • RNA modifications and cancer
  • Mitochondrial Function and Pathology
  • Retinal Development and Disorders
  • Metabolism and Genetic Disorders
  • Regulation of Appetite and Obesity

Helmut Fuchs has published numerous papers across prominent journals. Some of the recent publications include:

  • The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs, 2020, Genes & Development
  • Epigenetic inheritance of diet-induced and sperm-borne mitochondrial RNAs, 2024, Nature
  • Human and mouse essentiality screens as a resource for disease gene discovery, 2020, Nature Communications
  • A resource of targeted mutant mouse lines for 5,061 genes, 2021, Nature Genetics
  • METTL6 is a tRNA m3C methyltransferase that regulates pluripotency and tumor cell growth, 2020, Science Advances

Frequent coauthors in Helmut Fuchs's collaborations include:

  • Martin Hrabě de Angelis
  • Valérie Gailus-Durner
  • Birgit Rathkolb
  • Lore Becker
  • Wolfgang Wurst

In terms of publication venues, Helmut Fuchs has a substantial presence in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Mammalian Genome
  • Nature Communications
  • Science Advances
  • Scientific Reports

Best Publications

  • High-throughput discovery of novel developmental phenotypes

    Mary E. Dickinson;Ann M. Flenniken;Xiao Ji;Lydia Teboul

  • Cardioprotection and lifespan extension by the natural polyamine spermidine

    Tobias Eisenberg;Mahmoud Abdellatif;Sabrina Schroeder;Uwe Primessnig;Uwe Primessnig

  • Mutations in Dynein Link Motor Neuron Degeneration to Defects in Retrograde Transport

    Majid Hafezparast;Rainer Klocke;Christiana Ruhrberg;Andreas Marquardt

  • Genome-wide, large-scale production of mutant mice by ENU mutagenesis

    M. H. Hrabe de Angelis;H. Flaswinkel;H. Fuchs;B. Rathkolb

  • A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice

    Wolfgang Enard;Sabine Gehre;Kurt Hammerschmidt;Sabine M. Hölter

  • Aberrant methylation of tRNAs links cellular stress to neuro‐developmental disorders

    Sandra Blanco;Sabine Dietmann;Joana V Flores;Shobbir Hussain

  • A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains

    Michelle M Simon;Simon Greenaway;Jacqueline K White;Helmut Fuchs

  • Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.

    Christoph Kleinschnitz;Henrike Grund;Kirstin Wingler;Melanie Elise Armitage

  • Rapamycin extends murine lifespan but has limited effects on aging

    Frauke Neff;Diana Flores-Dominguez;Devon P. Ryan;Marion Horsch

  • Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects

    Kelly A McGowan;Jun Z Li;Jun Z Li;Christopher Y Park;Veronica Beaudry

  • An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice.

    Morag A Lewis;Elizabeth Quint;Anne M Glazier;Helmut Fuchs

  • Prevalence of sexual dimorphism in mammalian phenotypic traits

    Natasha A. Karp;Natasha A. Karp;Jeremy Mason;Arthur L. Beaudet;Yoav Benjamini

  • Beethoven, a mouse model for dominant, progressive hearing loss DFNA36.

    Sarah Vreugde;Alexandra Erven;Corné J. Kros;Walter Marcotti

  • Introducing the German Mouse Clinic: open access platform for standardized phenotyping

    Valérie Gailus-Durner;Helmut Fuchs;Lore Becker;Ines Bolle

  • Neuronal 3′,3,5-Triiodothyronine (T3) Uptake and Behavioral Phenotype of Mice Deficient in Mct8, the Neuronal T3 Transporter Mutated in Allan–Herndon–Dudley Syndrome

    Eva K Wirth;Stephan Roth;Cristiane Blechschmidt;Sabine M Hölter

  • Expression Pattern of G Protein-Coupled Receptor 30 in LacZ Reporter Mice

    Jörg Isensee;Luca Meoli;Valeria Zazzu;Christoph Nabzdyk

  • Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease

    Brian Finan;Christoffer Clemmensen;Zhimeng Zhu;Kerstin Stemmer

  • Effects of G-protein mutations on skin color

    Catherine D Van Raamsdonk;Karen R Fitch;Helmut Fuchs;Martin Hrabé de Angelis

  • Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts

    Johannes Keller;Philip Catala-Lehnen;Antje K. Huebner;Anke Jeschke

  • Autoimmunity and Inflammation Due to a Gain-of-Function Mutation in Phospholipase Cγ2 that Specifically Increases External Ca2+ Entry

    Philipp Yu;Rainer Constien;Neil Dear;Matilda Katan

Frequent Co-Authors

Valerie Gailus-Durner
Valerie Gailus-Durner Helmholtz Zentrum München
Martin Hrabé de Angelis
Martin Hrabé de Angelis Technical University of Munich
Eckhard Wolf
Eckhard Wolf Ludwig-Maximilians-Universität München
Wolfgang Wurst
Wolfgang Wurst German Center for Neurodegenerative Diseases
Thomas Klopstock
Thomas Klopstock Ludwig-Maximilians-Universität München
Martin Klingenspor
Martin Klingenspor Technical University of Munich
Dirk H. Busch
Dirk H. Busch Technical University of Munich
Jochen Graw
Jochen Graw Technical University of Munich
Johannes Beckers
Johannes Beckers Technical University of Munich
Markus Ollert
Markus Ollert University of Southern Denmark

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