Giampietro Schiavo spends much of his time researching Biochemistry, Cell biology, Synaptobrevin, Synaptic vesicle and Neurotoxin. The study of Biochemistry is intertwined with the study of Botulism in a number of ways. In the subject of general Cell biology, his work in Axoplasmic transport and Intracellular is often linked to ULK1, thereby combining diverse domains of study.
The concepts of his Axoplasmic transport study are interwoven with issues in Amyotrophic lateral sclerosis, Motor neuron and Neurodegeneration. Giampietro Schiavo has researched Synaptobrevin in several fields, including Molecular biology, Acetylcholine, Ganglioside binding and Synaptic vesicle docking. His work carried out in the field of Synaptic vesicle brings together such families of science as Integral membrane protein, Protease, Cholinergic and Syntaxin.
Giampietro Schiavo mostly deals with Cell biology, Biochemistry, Neuroscience, Axoplasmic transport and Synaptic vesicle. His Cell biology study incorporates themes from Exocytosis, Endocytic cycle, Neurotrophin and Mutant. His study on Biochemistry is mostly dedicated to connecting different topics, such as Botulism.
His biological study spans a wide range of topics, including Neurodegeneration and Anatomy. In his work, Gene is strongly intertwined with Amyotrophic lateral sclerosis, which is a subfield of Axoplasmic transport. The study incorporates disciplines such as Protease and Syntaxin in addition to Synaptic vesicle.
The scientist’s investigation covers issues in Cell biology, Axoplasmic transport, Neuroscience, Endosome and Neurodegeneration. His studies in Cell biology integrate themes in fields like Gene knockdown, RNA, RNA-binding protein, Amyotrophic lateral sclerosis and Mutant. The Amyotrophic lateral sclerosis study combines topics in areas such as Gene and Intron.
His Axoplasmic transport study integrates concerns from other disciplines, such as Nervous system, Motor neuron, Axon, Retrograde signaling and Organelle. His Neuroscience research is multidisciplinary, incorporating elements of Neuromuscular disease and Pathogenesis. His Endosome research is multidisciplinary, incorporating perspectives in Dynein, Endocytic cycle and Neurotrophin.
His primary areas of investigation include Cell biology, Axoplasmic transport, Endosome, Amyotrophic lateral sclerosis and Motor neuron. His Cell biology research integrates issues from Mutant and Gene. The various areas that Giampietro Schiavo examines in his Axoplasmic transport study include Pathogenesis, Spinal muscular atrophy, Nervous system, Microtubule and Organelle.
His Pathogenesis course of study focuses on Ubiquitin and Neuroscience. His research in Neuroscience intersects with topics in Acetylcholine and Denervation. The concepts of his Endosome study are interwoven with issues in Hippocampal formation, Tropomyosin receptor kinase B, Neurotrophin and Small GTPase.
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Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin
Giampietro G. Schiavo;Fabio Benfenati;Bernard Poulain;Ornella Rossetto.
Neurotoxins Affecting Neuroexocytosis
Giampietro Schiavo;Michela Matteoli;Cesare Montecucco.
Physiological Reviews (2000)
Mutations in Dynein Link Motor Neuron Degeneration to Defects in Retrograde Transport
Majid Hafezparast;Rainer Klocke;Christiana Ruhrberg;Andreas Marquardt.
Structure and function of tetanus and botulinum neurotoxins
Cesare Montecucco;Giampietro Schiavo.
Quarterly Reviews of Biophysics (1995)
Identification of the nerve terminal targets of botulinum neurotoxin serotypes A, D, and E.
G Schiavo;O Rossetto;S Catsicas;P Polverino de Laureto.
Journal of Biological Chemistry (1993)
Botulinum neurotoxins serotypes A and E cleave SNAP-25 at distinct COOH-terminal peptide bonds
Giampietro Schiavo;Annalisa Santucci;Bibhuti R. Dasgupta;Prashant P. Mehta.
FEBS Letters (1993)
Activation of MDA5 Requires Higher-Order RNA Structures Generated during Virus Infection
Andreas Pichlmair;Andreas Pichlmair;Oliver Schulz;Choon-Ping Tan;Jan Rehwinkel.
Journal of Virology (2009)
Rab5 and Rab7 Control Endocytic Sorting along the Axonal Retrograde Transport Pathway
Katrin Deinhardt;Sara Salinas;Carole Verastegui;Rose Watson.
Botulinum neurotoxin serotype F is a zinc endopeptidase specific for VAMP/synaptobrevin
G. Schiavo;C. C. Shone;O. Rossetto;F. C. G. Alexander.
Journal of Biological Chemistry (1993)
Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin
Giampietro Schiavo;Qu Ming Gu;Glenn D. Prestwich;Thomas H. Söllner.
Proceedings of the National Academy of Sciences of the United States of America (1996)
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