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Thomas H. Söllner

Thomas H. Söllner

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
23988
World Ranking
8471
National Ranking
620

Overview

Thomas H. Söllner is affiliated with Heidelberg University in Germany and specializes in the fields of Biochemistry, Genetics, and Molecular Biology. Their research primarily focuses on Molecular Biology, Cell Biology, and Cellular and Molecular Neuroscience, with additional work in Plant Science.

Their work encompasses a variety of topics, including:

  • Cellular transport and secretion
  • Lipid membrane structure and behavior
  • Neuroscience and neuropharmacology research
  • Nuclear structure and function
  • RNA research and splicing
  • Retinal development and disorders
  • Plant virus research studies

Their frequent co-authors include Jörg Malsam, Simon Bärfuss, Thorsten Trimbuch, Andreas F.-P. Sonnen, and Andrea Scheutzow.

Selected recent publications by Thomas H. Söllner illustrate the focus on synaptic transmission and molecular mechanisms:

  • "Complexin Suppresses Spontaneous Exocytosis by Capturing the Membrane-Proximal Regions of VAMP2 and SNAP25," published in Cell Reports in 2020
  • "The Interaction of Munc18-1 Helix 11 and 12 with the Central Region of the VAMP2 SNARE Motif Is Essential for SNARE Templating and Synaptic Transmission," published in eNeuro in 2020
  • "SNAP25 Disease Mutations Change the Energy Landscape for Synaptic Exocytosis Due to Aberrant SNARE Interactions," published in eLife in 2024
  • "A Short Perinuclear Amphipathic α-Helix in Apq12 Promotes Nuclear Pore Complex Biogenesis," published in Open Biology in 2021
  • "Arrangements of Proteins at Reconstituted Synaptic Vesicle Fusion Sites Depend on Membrane Separation," published in FEBS Letters in 2020

Thomas H. Söllner has published in various scientific venues, including:

  • Cell Reports
  • eNeuro
  • eLife
  • Open Biology
  • Biological Psychiatry

Best Publications

  • SNAP receptors implicated in vesicle targeting and fusion

    Thomas Söllner;Sidney W. Whiteheart;Michael Brunner;Hediye Erdjument-Bromage

  • SNAREpins: Minimal Machinery for Membrane Fusion

    Thomas Weber;Boris V Zemelman;James A McNew;Benedikt Westermann

  • A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion

    Thomas Söllner;Mark K. Bennett;Sidney W. Whiteheart;Richard H. Scheller

  • Compartmental specificity of cellular membrane fusion encoded in SNARE proteins

    James A. McNew;Francesco Parlati;Ryouichi Fukuda;Robert J. Johnston

  • A Rab Protein Is Required for the Assembly of SNARE Complexes in the Docking of Transport Vesicles

    Morten Søgaard;Katsuko Tani;R.Ruby Ye;Scott Geromanos

  • Bidirectional Transport by Distinct Populations of COPI-Coated Vesicles

    Lelio Orci;Mark Stamnes;Mariella Ravazzola;Mylène Amherdt

  • A mitochondrial import receptor for the ADP/ATP carrier.

    Thomas Söllner;Rupert Pfaller;Gareth Griffiths;Nikolaus Pfanner

  • Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses

    Giampietro Schiavo;Gudrun Stenbeck;James E. Rothman;Thomas H. Söllner

  • MOM19, an import receptor for mitochondrial precursor proteins

    Thomas Söllner;Gareth Griffiths;Rupert Pfaller;Nikolaus Pfanner

  • Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin

    Giampietro Schiavo;Qu Ming Gu;Glenn D. Prestwich;Thomas H. Söllner

  • Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors.

    James A. McNew;Thomas Weber;Francesco Parlati;Robert J. Johnston

  • Coupling of Coat Assembly and Vesicle Budding to Packaging of Putative Cargo Receptors

    Martina Bremser;Walter Nickel;Michael Schweikert;Mariella Ravazzola

  • Identification of a mitochondrial receptor complex required for recognition and membrane insertion of precursor proteins.

    Michael Kiebler;Rupert Pfaller;Rupert Pfaller;Thomas Söllner;Gareth Griffiths

  • Topological restriction of SNARE-dependent membrane fusion

    Francesco Parlati;James A. McNew;Ryouichi Fukuda;Rebecca Miller

  • Fusion of cells by flipped SNAREs

    Chuan Hu;Mahiuddin Ahmed;Thomas J. Melia;Thomas H. Söllner

  • Rapid and efficient fusion of phospholipid vesicles by the alpha-helical core of a SNARE complex in the absence of an N-terminal regulatory domain

    Francesco Parlati;Thomas Weber;James A. McNew;Benedikt Westermann

  • Multiple palmitoylation of synaptotagmin and the t-SNARE SNAP-25

    Michael Veit;Thomas H. Söllner;James E. Rothman

  • Functional architecture of an intracellular membrane t-SNARE

    Ryouichi Fukuda;James A. McNew;James A. McNew;Thomas Weber;Thomas Weber;Francesco Parlati

  • Ykt6p, a Prenylated SNARE Essential for Endoplasmic Reticulum-Golgi Transport

    James A. McNew;Morten Søgaard;Nina M. Lampen;Sachiko Machida

  • Membrane fusion: SNAREs and regulation.

    J. Malsam;S. Kreye;T. H. Söllner

Frequent Co-Authors

James E. Rothman
James E. Rothman Yale University
James A. McNew
James A. McNew Rice University
Mariella Ravazzola
Mariella Ravazzola University of Geneva
Giampietro Schiavo
Giampietro Schiavo University College London
Walter Neupert
Walter Neupert Max Planck Institute of Biochemistry
Lelio Orci
Lelio Orci University of Geneva
Mylène Amherdt
Mylène Amherdt University of Geneva
Nikolaus Pfanner
Nikolaus Pfanner University of Freiburg
Paul Tempst
Paul Tempst Memorial Sloan Kettering Cancer Center
Matthijs Verhage
Matthijs Verhage Vrije Universiteit Amsterdam

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