Edwin R. Chapman

Overview

Best Publications

• Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

  Juan Blasi;Juan Blasi;Edwin R. Chapman;Egenhard Link;Thomas Binz

  1522
  Citations

• SV2 is the protein receptor for botulinum neurotoxin A.

  Min Dong;Felix Yeh;William H. Tepp;Camin Dean

  922
  Citations

• How does synaptotagmin trigger neurotransmitter release

  Edwin R. Chapman

  747
  Citations

• Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC-1/syntaxin.

  J. Blasi;E.R. Chapman;S. Yamasaki;T. Binz

  700
  Citations

• Synaptotagmin: A Ca 2+ sensor that triggers exocytosis?

  Edwin R. Chapman

  626
  Citations

• Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine.

  L Edelmann;P I Hanson;E R Chapman;R Jahn

  584
  Citations

• Synaptophysin Regulates the Kinetics of Synaptic Vesicle Endocytosis in Central Neurons

  Sung E. Kwon;Edwin R. Chapman

  506
  Citations

• Ca2+ regulates the interaction between synaptotagmin and syntaxin 1.

  Edwin R. Chapman;Phyllis I. Hanson;Seong An;Reinhard Jahn

  483
  Citations

• Stability, affinity, and chromatic variants of the glutamate sensor iGluSnFR.

  Jonathan S. Marvin;Benjamin Scholl;Daniel E. Wilson;Kaspar Podgorski

  464
  Citations

• PIP2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membrane.

  Jihong Bai;Ward C Tucker;Edwin R Chapman

  452
  Citations

• Reconstitution of Ca2+-Regulated Membrane Fusion by Synaptotagmin and SNAREs

  Ward C. Tucker;Thomas Weber;Edwin R. Chapman

  441
  Citations

• The t-SNAREs syntaxin 1 and SNAP-25 are present on organelles that participate in synaptic vesicle recycling.

  C Walch-Solimena;J Blasi;L Edelmann;E R Chapman

  402
  Citations

• Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells

  Min Dong;David A. Richards;Michael C. Goodnough;William H. Tepp

  380
  Citations

• Transmembrane Segments of Syntaxin Line the Fusion Pore of Ca2+-Triggered Exocytosis

  Xue Han;Chih-Tien Wang;Jihong Bai;Edwin R. Chapman

  380
  Citations

• SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils.

  E R Chapman;S An;N Barton;R Jahn

  378
  Citations

• Synaptotagmin modulation of fusion pore kinetics in regulated exocytosis of dense-core vesicles.

  Chih-Tien Wang;Ruslan Grishanin;Cynthia A. Earles;Payne Y. Chang

  353
  Citations

• Kinetics of Synaptotagmin Responses to Ca2+ and Assembly with the Core SNARE Complex onto Membranes

  Anson F Davis;Jihong Bai;Dirk Fasshauer;Mark J Wolowick

  339
  Citations

• Synaptotagmin-Mediated Bending of the Target Membrane Is a Critical Step in Ca2+-Regulated Fusion

  Enfu Hui;Enfu Hui;Colin P. Johnson;Colin P. Johnson;Jun Yao;Jun Yao;F. Mark Dunning;F. Mark Dunning

  332
  Citations

• Direct Interaction of a Ca2+-binding Loop of Synaptotagmin with Lipid Bilayers

  Edwin R. Chapman;Anson F. Davis

  324
  Citations

• Calcium-dependent interaction of the cytoplasmic region of synaptotagmin with membranes. Autonomous function of a single C2-homologous domain.

  E R Chapman;R Jahn

  292
  Citations