2026 Loren L. Looger: Neuroscience Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Neuroscience	86	1271	1150	646	571	197	41552
Biology and Biochemistry	86	2912	2679	1493	1344	251	41761

Research.com Recognitions

2015 - W. Alden Spencer Award, College of Physicians and Surgeons

Overview

Loren L. Looger is affiliated with the Howard Hughes Medical Institute in the United States. Their research spans multiple interconnected fields, primarily within biochemistry, genetics, molecular biology, and neuroscience. This interdisciplinary focus is reflected in their body of work covering molecular biology, cellular and molecular neuroscience, cognitive neuroscience, biophysics, and immunology.

Their publications frequently appear in several specialized venues. The most common include bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Nature Methods, SSRN Electronic Journal, and Biophysical Journal. These venues highlight their engagement with cutting-edge developments across molecular biology and neuroscience research.

Their research topics reveal a broad yet specific emphasis on:

Neuroscience and neuropharmacology research
Photoreceptor and optogenetics research
Neural dynamics and brain function
Receptor mechanisms and signaling
Advanced fluorescence microscopy techniques
Protein structure and dynamics
Systemic lupus erythematosus research

Loren L. Looger has coauthored extensively, collaborating with several researchers multiple times. The most frequent coauthors include:

Jonathan S. Marvin
Henry A. Lester
J. Hasseman
Swapan K. Nath
Lauren L. Porter

Recent significant publications by Loren L. Looger include:

Fast and sensitive GCaMP calcium indicators for imaging neural populations (2023, Nature)
Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning (2020, Cell)
Glutamate indicators with improved activation kinetics and localization for imaging synaptic transmission (2023, Nature Methods)
Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b (2020, Science)
A fast genetically encoded fluorescent sensor for faithful in vivo acetylcholine detection in mice, fish, worms and flies (2020, bioRxiv [Cold Spring Harbor Laboratory])

In 2015, Loren L. Looger received the W. Alden Spencer Award from the College of Physicians and Surgeons.

Best Publications

Ultrasensitive fluorescent proteins for imaging neuronal activity.

Tsai Wen Chen;Trevor J. Wardill;Trevor J. Wardill;Yi Sun;Stefan R. Pulver

7210
Citations
Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

Lin Tian;S Andrew Hires;Tianyi Mao;Daniel Huber

2349
Citations
Shared and distinct transcriptomic cell types across neocortical areas

Bosiljka Tasic;Zizhen Yao;Lucas T. Graybuck;Kimberly A. Smith

1978
Citations
Optimization of a GCaMP calcium indicator for neural activity imaging.

Jasper Akerboom;Tsai Wen Chen;Trevor J. Wardill;Lin Tian;Lin Tian

1514
Citations
A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons.

D. Gowanlock R. Tervo;Bum Yeol Hwang;Sarada Viswanathan;Thomas Gaj

1262
Citations
High-performance calcium sensors for imaging activity in neuronal populations and microcompartments

Hod Dana;Hod Dana;Yi Sun;Yi Sun;Boaz Mohar;Brad K. Hulse

1241
Citations
Sensitive red protein calcium indicators for imaging neural activity

Hod Dana;Boaz Mohar;Boaz Mohar;Yi Sun;Sujatha Narayan

1152
Citations
An optimized fluorescent probe for visualizing glutamate neurotransmission

Jonathan S. Marvin;Bart G. Borghuis;Bart G. Borghuis;Lin Tian;Lin Tian;Joseph Cichon

1126
Citations
Functional imaging of hippocampal place cells at cellular resolution during virtual navigation

Daniel A Dombeck;Christopher D Harvey;Lin Tian;Loren L Looger

1018
Citations
Computational design of receptor and sensor proteins with novel functions

Loren L. Looger;Mary A. Dwyer;James J. Smith;Homme W. Hellinga

921
Citations
Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics.

Jasper Akerboom;Nicole Carreras Calderón;Nicole Carreras Calderón;Nicole Carreras Calderón;Lin Tian;Lin Tian;Sebastian Wabnig

878
Citations
A bright and photostable photoconvertible fluorescent protein

Sean A McKinney;Christopher S Murphy;Kristin L Hazelwood;Michael W Davidson

665
Citations
Thy1-GCaMP6 Transgenic Mice for Neuronal Population Imaging In Vivo

Hod Dana;Tsai Wen Chen;Amy Hu;Brenda C. Shields

656
Citations
Multiple dynamic representations in the motor cortex during sensorimotor learning

Daniel Huber;D.A. Gutnisky;S. Peron;D. H. O’Connor

585
Citations
Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall

Yang Xiang;Quan Yuan;Nina Vogt;Loren L. Looger

530
Citations
Labeling of active neural circuits in vivo with designed calcium integrators

Benjamin F. Fosque;Yi Sun;Hod Dana;Chao-Tsung Yang

519
Citations
Stability, affinity, and chromatic variants of the glutamate sensor iGluSnFR.

Jonathan S. Marvin;Benjamin Scholl;Daniel E. Wilson;Kaspar Podgorski

464
Citations
Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors

Sakiko Okumoto;Loren L. Looger;Kristina D. Micheva;Richard J. Reimer

448
Citations
Computational Design of a Biologically Active Enzyme

Mary A. Dwyer;Loren L. Looger;Homme W. Hellinga

433
Citations
A Cre-Dependent GCaMP3 Reporter Mouse for Neuronal Imaging In Vivo

Hatim A. Zariwala;Hatim A. Zariwala;Hatim A. Zariwala;Bart G. Borghuis;Bart G. Borghuis;Tycho M. Hoogland;Linda Madisen

426
Citations
Distinct descending motor cortex pathways and their roles in movement

Michael N. Economo;Sarada Viswanathan;Bosiljka Tasic;Erhan Bas

420
Citations
Construction of a fluorescent biosensor family

Robert M. De Lorimier;J. Jeff Smith;Mary A. Dwyer;Loren L. Looger

416
Citations
Nanotools for Neuroscience and Brain Activity Mapping

A. Paul Alivisatos;Anne M. Andrews;Edward S. Boyden;Miyoung Chun

408
Citations

Frequent Co-Authors

Karel Svoboda Allen Institute

Wolf B. Frommer Heinrich Heine University Düsseldorf

Homme W. Hellinga Duke University

Vivek Jayaraman Howard Hughes Medical Institute

Henry A. Lester California Institute of Technology

Swapan K. Nath Oklahoma Medical Research Foundation

John B. Harley United States Department of Veterans Affairs

Jonathan B. Demb Yale University

Misha B. Ahrens Howard Hughes Medical Institute

Cornelia I. Bargmann Rockefeller University

External Links

Personal website of Loren L. Looger

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