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Ori D. Rotstein

Ori D. Rotstein

D-Index & Metrics

Biology and Biochemistry

D-Index
86
Citations
21991
World Ranking
3034
National Ranking
96

Overview

Ori D. Rotstein is affiliated with the University of Toronto in Canada and has made contributions primarily in the field of Medicine. Their research spans multiple subfields including Surgery, Pulmonary and Respiratory Medicine, Cardiology and Cardiovascular Medicine, Molecular Biology, and Endocrinology, Diabetes and Metabolism.

Their recent publications cover a range of topics and have appeared in several notable journals. Recent papers include:

  • Non-steroidal mineralocorticoid receptor antagonists in cardiorenal disease, 2022, European Heart Journal
  • GLP-1 receptor agonists and atherosclerosis protection: the vascular endothelium takes center stage, 2024, American Journal of Physiology-Heart and Circulatory Physiology
  • Electrical impedance tomography-guided positive end-expiratory pressure titration in ARDS: a systematic review and meta-analysis, 2024, Intensive Care Medicine
  • Therapeutic Effects of Mesenchymal Stromal Cells Require Mitochondrial Transfer and Quality Control, 2023, International Journal of Molecular Sciences
  • Fatty acid binding protein 3 is associated with peripheral arterial disease, 2020, JVS Vascular Science

Frequent co-authors in their research efforts include:

  • Charles de Mestral
  • Derek Beaton
  • Douglas S. Lee
  • Duminda N. Wijeysundera
  • Muhammad Mamdani

Their work has been published repeatedly in several key venues, indicating consistent research output in these outlets. These venues are:

  • Journal of Vascular Surgery
  • International Journal of Molecular Sciences
  • Annals of Surgery
  • European Heart Journal
  • bioRxiv (Cold Spring Harbor Laboratory)

Research topics addressed by Ori D. Rotstein include:

  • Cardiac, Anesthesia and Surgical Outcomes
  • Peripheral Artery Disease Management
  • Aortic aneurysm repair treatments
  • Cerebrovascular and Carotid Artery Diseases
  • Diabetes Treatment and Management
  • Organ Transplantation Techniques and Outcomes
  • Venous Thromboembolism Diagnosis and Management

Their research involves multi-disciplinary approaches often intersecting clinical and molecular domains, particularly involving therapies, diagnostics, and surgical outcomes related to vascular and cardiovascular diseases.

Best Publications

  • Pre–B cell colony–enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis

    Song Hui Jia;Yue Li;Jean Parodo;Andras Kapus

  • Trial of Short-Course Antimicrobial Therapy for Intraabdominal Infection

    Robert G. Sawyer;Jeffrey A. Claridge;Avery B. Nathens;Ori D. Rotstein

  • Dysregulated Expression of Neutrophil Apoptosis in the Systemic Inflammatory Response Syndrome

    Maria F. Jimenez;R. William G. Watson;Jean Parodo;David Evans

  • Ribavirin Inhibits Viral-Induced Macrophage Production of TNF, IL-1, the Procoagulant fgl2 Prothrombinase and Preserves Th1 Cytokine Production But Inhibits Th2 Cytokine Response

    Qin Ning;D. Brown;J. Parodo;M. Cattral

  • Central role for Rho in TGF-β1-induced α-smooth muscle actin expression during epithelial-mesenchymal transition

    András Masszi;András Masszi;Caterina Di Ciano;Gábor Sirokmány;William T. Arthur

  • Nonopsonic monocyte/macrophage phagocytosis of Plasmodium falciparum-parasitized erythrocytes: a role for CD36 in malarial clearance

    Ian D. McGilvray;Lena Serghides;Andras Kapus;Ori D. Rotstein

  • Integrity of Cell-Cell Contacts Is a Critical Regulator of TGF-β1-Induced Epithelial-to-Myofibroblast Transition : Role for β-Catenin

    András Masszi;Lingzhi Fan;László Rosivall;László Rosivall;Christopher A. McCulloch

  • Immunomodulatory Effects of Hypertonic Resuscitation on the Development of Lung Inflammation Following Hemorrhagic Shock

    Sandro B. Rizoli;Andras Kapus;Jie Fan;Yue H. Li

  • The immunomodulatory effects of hypertonic saline resuscitation in patients sustaining traumatic hemorrhagic shock : A randomized, controlled, double-blinded trial

    Sandro B. Rizoli;Shawn G. Rhind;Pang N. Shek;Kenji Inaba

  • Phagosomal acidification is mediated by a vacuolar-type H(+)-ATPase in murine macrophages.

    G L Lukacs;O D Rotstein;S Grinstein

  • Delayed neutrophil apoptosis in sepsis is associated with maintenance of mitochondrial transmembrane potential and reduced caspase-9 activity.

    Ravi Taneja;Jean Parodo;Song Hui Jia;Andras Kapus

  • Results of a randomized trial comparing sequential intravenous/oral treatment with ciprofloxacin plus metronidazole to imipenem/cilastatin for intra-abdominal infections

    Joseph Solomkin;Harald Reinhart;E. Dellinger;John Bohnen

  • Ertapenem Versus Piperacillin/Tazobactam in the Treatment of Complicated Intraabdominal Infections: Results of a Double-Blind, Randomized Comparative Phase III Trial

    Joseph S. Solomkin;Albert E. Yellin;Ori D. Rotstein;Nicolas V. Christou

  • Neutrophil apoptosis is modulated by endothelial transmigration and adhesion molecule engagement

    R. W. G. Watson;O. D. Rotstein;A. B. Nathens;J. Parodo

  • Host Resistance to Intracellular Infection: Mutation of Natural Resistance-associated Macrophage Protein 1 (Nramp1) Impairs Phagosomal Acidification

    David J. Hackam;Ori D. Rotstein;Wei Jian Zhang;Samantha Gruenheid

  • Prevalence and Causes of Attrition Among Surgical Residents: A Systematic Review and Meta-analysis

    Zeyad Khoushhal;Mohamad A. Hussain;Elisa Greco;Muhammad Mamdani

  • Mechanism of decreased in vitro murine macrophage cytokine release after exposure to carbon dioxide: relevance to laparoscopic surgery.

    Michael A. West;David J. Hackam;Jeffrey Baker;Jorge L. Rodriguez

  • Hemorrhagic Shock Primes for Increased Expression of Cytokine-Induced Neutrophil Chemoattractant in the Lung: Role in Pulmonary Inflammation Following Lipopolysaccharide

    Jie Fan;John C. Marshall;Maria Jimenez;Pang N. Shek

  • The IL-1 beta-converting enzyme (caspase-1) inhibits apoptosis of inflammatory neutrophils through activation of IL-1 beta.

    R. William;G. Watson;Ori D. Rotstein;Jean Parodo

  • Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages.

    Kinga A. Powers;Katalin Szászi;Rachel G. Khadaroo;Patrick S. Tawadros

Frequent Co-Authors

Andras Kapus
Andras Kapus University of Toronto
John C. Marshall
John C. Marshall University of Toronto
David J. Hackam
David J. Hackam Johns Hopkins University School of Medicine
Timothy L. Pruett
Timothy L. Pruett University of Minnesota
Jie Fan
Jie Fan Zhejiang University
Richard L. Simmons
Richard L. Simmons University of Pittsburgh
Nancy N. Baxter
Nancy N. Baxter University of Sydney
Gary A. Levy
Gary A. Levy University of Toronto
Joseph S. Solomkin
Joseph S. Solomkin University of Cincinnati Medical Center

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