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Thomas E. DeCoursey

Thomas E. DeCoursey

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
11967
World Ranking
11462
National Ranking
4952

Overview

Thomas E. DeCoursey is a researcher affiliated with Rush University in the United States. Their academic work primarily focuses on biochemistry, genetics, and molecular biology, with a significant emphasis on molecular biology. Additional subfields of study include cellular and molecular neuroscience, cardiology and cardiovascular medicine, pathology and forensic medicine, and spectroscopy.

Their main research topics cover a range of areas related to ion channels and electrical activity in biological systems. These topics include:

  • Ion channel regulation and function
  • Cardiac electrophysiology and arrhythmias
  • Nicotinic acetylcholine receptors study
  • Neuroscience and neuropharmacology research
  • Lipid membrane structure and behavior
  • Photoreceptor and optogenetics research
  • Mitochondrial function and pathology

DeCoursey has contributed to multiple peer-reviewed publications, appearing in journals such as Biophysical Journal, bioRxiv (Cold Spring Harbor Laboratory), The Journal of Physiology, PLoS ONE, and Annual Review of Physiology. Among these venues, Biophysical Journal features seven of their publications, followed by two in bioRxiv.

Selected recent papers by Thomas E. DeCoursey include:

  • "The HVCN1 voltage-gated proton channel contributes to pH regulation in canine ventricular myocytes," 2022, The Journal of Physiology
  • "Expression and function of voltage gated proton channels (Hv1) in MDA-MB-231 cells," 2020, PLoS ONE
  • "Engineered high-affinity zinc binding site reveals gating configurations of a human proton channel," 2020, The Journal of General Physiology
  • "Transcendent Aspects of Proton Channels," 2023, Annual Review of Physiology
  • "Analysis of an electrostatic mechanism for ΔpH dependent gating of the voltage-gated proton channel, HV1, supports a contribution of protons to gating charge," 2021, Biochimica et Biophysica Acta (BBA) - Bioenergetics

Frequent collaborators in their research include Vladimir V. Cherny, Boris Musset, Artem G. Ayuyan, Deri Morgan, and Gustavo Chaves.

Best Publications

  • Voltage-gated K + channels in human T lymphocytes: a role in mitogenesis?

    Thomas E. DeCoursey;K. George Chandy;Sudhir Gupta;Michael D. Cahalan

  • Voltage-Gated Proton Channels and Other Proton Transfer Pathways

    Thomas E. Decoursey

  • A voltage-gated potassium channel in human T lymphocytes.

    M D Cahalan;K G Chandy;T E DeCoursey;S Gupta

  • Voltage-gated potassium channels are required for human T lymphocyte activation.

    K G Chandy;T E DeCoursey;M D Cahalan;C McLaughlin

  • Regulation and termination of NADPH oxidase activity.

    T. E. DeCoursey;E. Ligeti

  • The voltage dependence of NADPH oxidase reveals why phagocytes need proton channels

    Thomas E. DeCoursey;Deri Morgan;Vladimir V. Cherny

  • HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species

    Melania Capasso;Mandeep K Bhamrah;Tom Henley;Robert S Boyd

  • Voltage-Gated Proton Channels: Molecular Biology, Physiology, and Pathophysiology of the HV Family

    Thomas E. DeCoursey

  • Voltage-dependent ion channels in T-lymphocytes.

    T.E. DeCoursey;K.G. Chandy;S. Gupta;M.D. Cahalan

  • Aspartate 112 is the selectivity filter of the human voltage-gated proton channel

    Boris Musset;Susan M. E. Smith;Sindhu Rajan;Deri Morgan

  • Potential, pH, and arachidonate gate hydrogen ion currents in human neutrophils.

    T.E. DeCoursey;V.V. Cherny

  • NOX5 in human spermatozoa: Expression, function, and regulation

    Boris Musset;Robert A. Clark;Thomas E. DeCoursey;Gabor L. Petheo

  • Intrinsic gating of inward rectifier in bovine pulmonary artery endothelial cells in the presence or absence of internal Mg2

    Michael R. Silver;Thomas E. Decoursey

  • Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis

    Deri Morgan;Melania Capasso;Boris Musset;Vladimir V. Cherny

  • Mitogen induction of ion channels in murine T lymphocytes.

    T E Decoursey;K G Chandy;S Gupta;M D Cahalan

  • Charge compensation during the phagocyte respiratory burst.

    Ricardo Murphy;Thomas E. DeCoursey

  • Hydrogen ion currents in rat alveolar epithelial cells.

    T.E. DeCoursey

  • Two types of potassium channels in murine T lymphocytes.

    T E Decoursey;K G Chandy;S Gupta;M D Cahalan

  • Simultaneous activation of NADPH oxidase-related proton and electron currents in human neutrophils

    T. E. DeCoursey;V. V. Cherny;W. Zhou;L. L. Thomas

  • Voltage-gated proton channel in a dinoflagellate

    Susan M. E. Smith;Deri Morgan;Boris Musset;Vladimir V. Cherny

Frequent Co-Authors

Régis Pomès
Régis Pomès University of Toronto
Sudhir Gupta
Sudhir Gupta University of California, Irvine
Michael D. Cahalan
Michael D. Cahalan University of California, Irvine
Martin J. S. Dyer
Martin J. S. Dyer University of Leicester
J. Woodland Hastings
J. Woodland Hastings Harvard University
Eduardo Ríos
Eduardo Ríos Rush University
K. George Chandy
K. George Chandy Nanyang Technological University
Carmay Lim
Carmay Lim Academia Sinica
Mary C. Dinauer
Mary C. Dinauer Washington University in St. Louis
Randy D. Gascoyne
Randy D. Gascoyne BC Cancer Agency

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