D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 57 Citations 14,724 103 World Ranking 9252 National Ranking 37

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Genetics
  • Internal medicine

The scientist’s investigation covers issues in Potassium channel, Pharmacology, Cell biology, Ion channel and Biochemistry. He combines subjects such as Stichodactyla helianthus, Inward-rectifier potassium ion channel, KCNN4 and Channel blocker with his study of Potassium channel. The various areas that K. George Chandy examines in his Stichodactyla helianthus study include Cytotoxic T cell, In vitro, Molecular biology, Flow cytometry and Microfold cell.

His Pharmacology study combines topics in areas such as Voltage-gated ion channel and Potassium channel blocker. His Cell biology research includes themes of Gating, Mutant, SK channel, Calmodulin and Membrane potential. His study looks at the relationship between Ion channel and topics such as Patch clamp, which overlap with Immunology, Cellular immunity, Immune system, Lymphocyte and Calcium channel.

His most cited work include:

  • International Union of Pharmacology. LIII. Nomenclature and Molecular Relationships of Voltage-Gated Potassium Channels (814 citations)
  • Voltage-gated K + channels in human T lymphocytes: a role in mitogenesis? (632 citations)
  • International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels : potassium channels (544 citations)

What are the main themes of his work throughout his whole career to date?

K. George Chandy mainly investigates Potassium channel, Cell biology, Immunology, Pharmacology and T cell. His biological study spans a wide range of topics, including Toxin, Biochemistry, Peptide and Stereochemistry. His research in Cell biology intersects with topics in SK channel and Patch clamp.

His Pharmacology research is multidisciplinary, relying on both Voltage-gated ion channel, Calcium and Stichodactyla helianthus. He works mostly in the field of T cell, limiting it down to topics relating to Cytotoxic T cell and, in certain cases, Molecular biology and Flow cytometry. In his research on the topic of Potassium channel blocker, Ion channel is strongly related with Channel blocker.

He most often published in these fields:

  • Potassium channel (45.74%)
  • Cell biology (23.40%)
  • Immunology (20.21%)

What were the highlights of his more recent work (between 2012-2019)?

  • Potassium channel (45.74%)
  • Pharmacology (17.02%)
  • Cell biology (23.40%)

In recent papers he was focusing on the following fields of study:

Potassium channel, Pharmacology, Cell biology, Calcium and K channels are his primary areas of study. His research in Potassium channel intersects with topics in TRPC1, Biochemistry and C-terminus. The various areas that K. George Chandy examines in his Pharmacology study include Pathology, Blockade and Stichodactyla helianthus.

His study in Cell biology is interdisciplinary in nature, drawing from both Helminths, Immune system and Immunology. His Calcium research is multidisciplinary, incorporating elements of Non alcoholic, Subfamily, Stereochemistry, Disease and hERG. The study incorporates disciplines such as T cell, Matrix metalloproteinase, Intracellular and Peptide in addition to Function.

Between 2012 and 2019, his most popular works were:

  • Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance (52 citations)
  • Blockade of Kv1.3 channels ameliorates radiation-induced brain injury. (38 citations)
  • Intracellular Trafficking of the KV1.3 Potassium Channel Is Regulated by the Prodomain of a Matrix Metalloprotease (18 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Genetics
  • Internal medicine

His scientific interests lie mostly in Endocrinology, Fatty liver, Diabetes mellitus, Leptin and Internal medicine. In his articles, he combines various disciplines, including Endocrinology and Thermogenin.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

International Union of Pharmacology. LIII. Nomenclature and Molecular Relationships of Voltage-Gated Potassium Channels

Aguan D. Wei;George A. Gutman;Richard W Aldrich;K. George Chandy.
Pharmacological Reviews (2005)

1109 Citations

Voltage-gated K + channels in human T lymphocytes: a role in mitogenesis?

Thomas E. DeCoursey;K. George Chandy;Sudhir Gupta;Michael D. Cahalan.
Nature (1984)

882 Citations

Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: A potential immunosuppressant

Heike Wulff;Mark J. Miller;Wolfram Hänsel;Stephan Grissmer.
Proceedings of the National Academy of Sciences of the United States of America (2000)

702 Citations

Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases

Christine Beeton;Heike Wulff;Nathan E. Standifer;Philippe Azam.
Proceedings of the National Academy of Sciences of the United States of America (2006)

562 Citations

International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels : potassium channels

George A. Gutman;K. George Chandy;John P. Adelman;Jayashree Aiyar.
Pharmacological Reviews (2003)

560 Citations

K+ channels as targets for specific immunomodulation.

K. George Chandy;Heike Wulff;Christine Beeton;Michael Pennington.
Trends in Pharmacological Sciences (2004)

542 Citations

The functional network of ion channels in T lymphocytes

Michael D. Cahalan;K. George Chandy.
Immunological Reviews (2009)

529 Citations

The voltage-gated Kv1.3 K+ channel in effector memory T cells as new target for MS

Heike Wulff;Peter A. Calabresi;Rameeza Allie;Sung Yun.
Journal of Clinical Investigation (2003)

513 Citations

Up-regulation of the IKCa1 Potassium Channel during T-cell Activation MOLECULAR MECHANISM AND FUNCTIONAL CONSEQUENCES

Sanjiv Ghanshani;Heike Wulff;Mark J. Miller;Heike Rohm.
Journal of Biological Chemistry (2000)

482 Citations

A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies.

Jan Tytgat;K.George Chandy;Maria L Garcia;George A Gutman.
Trends in Pharmacological Sciences (1999)

467 Citations

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