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Karen N. Conneely

Karen N. Conneely

D-Index & Metrics

Genetics

D-Index
55
Citations
17460
World Ranking
3545
National Ranking
1539

Research.com Recognitions

  • 2008 - C.W. Cotterman Award, American Society of Human Genetics

Overview

Karen N. Conneely is affiliated with Emory University in the United States and has contributed extensively to research primarily in biochemistry, genetics, and molecular biology, with a substantial number of publications also spanning medicine.

Their work is concentrated in key subfields including molecular biology, genetics, health, toxicology and mutagenesis, pediatrics, perinatology and child health, as well as sociology and political science. This multidisciplinary approach reflects a focus on biological and health sciences interconnected with societal factors.

The main topics explored in their research include epigenetics and DNA methylation; genetic syndromes and imprinting; birth, development, and health; air quality and health impacts; genetic associations and epidemiology; RNA modifications and cancer; and inflammatory bowel disease.

Frequently collaborating with other researchers, Karen N. Conneely has coauthored multiple publications with Alicia K. Smith, Andrea Baccarelli, Eric A. Whitsel, Andrew H. Miller, and Jan Bressler. These collaborations have contributed to advancing understanding in their core fields of study.

Their research has been published in several venues, with the highest numbers in bioRxiv (Cold Spring Harbor Laboratory) and UNC Libraries. Other frequent publication outlets include the International Journal of Radiation Oncology*Biology*Physics, Nature Communications, and Epigenomics.

Among notable recent papers by Karen N. Conneely are:

  • Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging, 2021, Genome Biology
  • DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases, 2022, Nature Communications
  • Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease, 2022, Nature Communications
  • Brain DNA Methylation Patterns in CLDN5 Associated With Cognitive Decline, 2021, Biological Psychiatry
  • Epigenetic age acceleration, fatigue, and inflammation in patients undergoing radiation therapy for head and neck cancer: A longitudinal study, 2021, Cancer

Karen N. Conneely received the C.W. Cotterman Award from the American Society of Human Genetics in 2008, marking recognition within the scientific community.

Best Publications

  • A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.

    Laura J. Scott;Karen L. Mohlke;Lori L. Bonnycastle;Cristen J. Willer

  • Epigenetic Signatures of Cigarette Smoking

    Roby Joehanes;Allan C. Just;Riccardo E. Marioni;Luke C. Pilling

  • The transcriptional landscape of age in human peripheral blood

    Marjolein J. Peters;Roby Joehanes;Luke C. Pilling;Claudia Schurmann;Claudia Schurmann

  • Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder

    Divya Mehta;Torsten Klengel;Karen N. Conneely;Alicia K. Smith

  • So many correlated tests, so little time! Rapid adjustment of P values for multiple correlated tests.

    Karen N. Conneely;Michael Boehnke

  • A Bayesian hierarchical model to detect differentially methylated loci from single nucleotide resolution sequencing data

    Hao Feng;Karen N. Conneely;Hao Wu

  • Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome

    Brian C. Capell;Michael R. Erdos;James P. Madigan;James J. Fiordalisi

  • Age-associated DNA methylation in pediatric populations

    Reid S. Alisch;Benjamin G. Barwick;Pankaj Chopra;Leila K. Myrick

  • Differential Immune System DNA Methylation and Cytokine Regulation in Post-Traumatic Stress Disorder

    Alicia K. Smith;Karen N. Conneely;Varun Kilaru;Kristina B. Mercer

  • A DNA methylation biomarker of alcohol consumption.

    C Liu;R E Marioni;R E Marioni;Åsa K Hedman;L Pfeiffer

  • DNA extracted from saliva for methylation studies of psychiatric traits: Evidence tissue specificity and relatedness to brain

    Alicia K. Smith;Varun Kilaru;Torsten Klengel;Torsten Klengel;Kristina B. Mercer

  • Genetic Variation Near the Hepatocyte Nuclear Factor-4α Gene Predicts Susceptibility to Type 2 Diabetes

    Kaisa Silander;Karen L. Mohlke;Laura J. Scott;Erin C. Peck

  • Detection of differentially methylated regions from whole-genome bisulfite sequencing data without replicates.

    Hao Wu;Tianlei Xu;Hao Feng;Li Chen

  • DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

    Symen Ligthart;Carola Marzi;Stella Aslibekyan;Michael M. Mendelson;Michael M. Mendelson;Michael M. Mendelson

  • Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence

    Lavinia Gordon;Jihoon E. Joo;Joseph E. Powell;Joseph E. Powell;Miina Ollikainen

  • An epigenetic clock for gestational age at birth based on blood methylation data.

    Anna K. Knight;Jeffrey M. Craig;Christiane Theda;Marie Bækvad-Hansen

  • Methylation quantitative trait loci (meQTLs) are consistently detected across ancestry, developmental stage, and tissue type

    Alicia K Smith;Varun Kilaru;Mehmet Kocak;Lynn M Almli

  • Accounting for Population Stratification in DNA Methylation Studies

    Richard T. Barfield;Lynn M. Almli;Varun Kilaru;Alicia K. Smith

  • CpGassoc: an R function for analysis of DNA methylation microarray data

    Richard T. Barfield;Varun Kilaru;Alicia K. Smith;Karen N. Conneely

  • A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model

    Brian C. Capell;Michelle Olive;Michael R. Erdos;Kan Cao

Frequent Co-Authors

Kerry J. Ressler
Kerry J. Ressler Harvard University
Elisabeth B. Binder
Elisabeth B. Binder Max Planck Society
Bekh Bradley
Bekh Bradley Emory University
Andrea Baccarelli
Andrea Baccarelli Columbia University
Michael P. Epstein
Michael P. Epstein Emory University
Myriam Fornage
Myriam Fornage The University of Texas Health Science Center at Houston
Jaakko Tuomilehto
Jaakko Tuomilehto University of Helsinki
Steve Horvath
Steve Horvath University of California, Los Angeles
Yun Li
Yun Li University of North Carolina at Chapel Hill
Francis S. Collins
Francis S. Collins National Institutes of Health

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